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Mark Gerstein

Researcher at Yale University

Publications -  802
Citations -  172183

Mark Gerstein is an academic researcher from Yale University. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 168, co-authored 751 publications receiving 149578 citations. Previous affiliations of Mark Gerstein include Rutgers University & Structural Genomics Consortium.

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Genomic variants concurrently listed in a somatic and a germline mutation database have implications for disease-variant discovery and genomic privacy

TL;DR: It is found that three times as many variants are shared between the soma and germline than is expected by independence, and a new, general-purpose statistical framework is developed to explain the observed excess of cSNVs in terms of the varying mutation rates of different kinds substitution types and of genomic regions.
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The association between evening social media use and delayed sleep may be causal: Suggestive evidence from 120 million Reddit timestamps.

TL;DR: The authors found that users are especially likely to be active on Reddit after their bedtime (and therefore awake) on nights that they posted to Reddit shortly before bedtime, especially if they posted multiple times or in high-engagement forums that night.

K-mer Analysis on Developmental and Housekeeping Enhancer Peaks

TL;DR: In this paper, the authors propose a method to solve the problem of self-diagnosis in cancer patients, and propose an approach to diagnose self-declarative cancer patients.
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Constructing a full, multiple-layer interactome for SARS-CoV-2 in the context of lung disease: Linking the virus with human genes and microbes

TL;DR: In this paper , a statistical modeling approach called MLCrosstalk based on latent Dirichlet allocation was developed to construct the full interactome of SARS-CoV-2 infection, which incorporates human microRNAs (miRNAs), additional human protein-coding genes, and exogenous microbes.

transcript within the human HOXA cluster A myelopoiesis-associated regulatory intergenic non-coding RNA

TL;DR: This dissertation aims to provide a history of quantitative anaesthetism from 1989 to 2002, a period chosen in order to explore its roots as well as specific cases up to and including the year in which descriptions of “black-box surgery” began to circulate.