Simona Volpi

TL;DR: This trial will provide data on the clinical utility of CYP2D6 phenotype‐guided opioid selection for improving postoperative pain control and reducing opioid‐related risks.

TL;DR: The ethical implications of pathology incidental findings in the Genotype-Tissue Expression (GTEx) project, the process for developing a consensus approach as to if/when such findings should be returned, possible implications for other research projects collecting postmortem tissues and how the scenario encountered in GTEx fits into the larger return of results/incidental findings debate are described.

TL;DR: In this article, the authors proposed a new method for the detection of cancer using a set of genes extracted from the human brain, which they called LSTM-CRF.

TL;DR: The GUARDD-US trial as discussed by the authors evaluated the relationship of pharmacogenomic genotype and change in systolic BP between baseline and 3 months in individuals with two APOL1 risk alleles.