H
He Gao
Researcher at National University of Singapore
Publications - 14
Citations - 955
He Gao is an academic researcher from National University of Singapore. The author has contributed to research in topics: Adiponectin & Insulin resistance. The author has an hindex of 13, co-authored 14 publications receiving 767 citations. Previous affiliations of He Gao include Karolinska Institutet.
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A catalog of genetic loci associated with kidney function from analyses of a million individuals
Matthias Wuttke,Yong Li,Man Li,Karsten B. Sieber,Mary F. Feitosa,Mathias Gorski,Adrienne Tin,Lihua Wang,Audrey Y. Chu,Anselm Hoppmann,Holger Kirsten,Ayush Giri,Jin-Fang Chai,Gardar Sveinbjornsson,Bamidele O. Tayo,Teresa Nutile,Christian Fuchsberger,Jonathan Marten,Massimiliano Cocca,Sahar Ghasemi,Yizhe Xu,Katrin Horn,Damia Noce,Peter J. van der Most,Sanaz Sedaghat,Zhi Yu,Masato Akiyama,Saima Afaq,Tarunveer S. Ahluwalia,Peter Almgren,Najaf Amin,Johan Ärnlöv,Stephan J. L. Bakker,Nisha Bansal,Daniela Baptista,Sven Bergmann,Mary L. Biggs,Ginevra Biino,Michael Boehnke,Eric Boerwinkle,Mathilde Boissel,Erwin P. Bottinger,Thibaud Boutin,Hermann Brenner,Marco Brumat,Ralph Burkhardt,Adam S. Butterworth,Eric Campana,Archie Campbell,Harry Campbell,Mickaël Canouil,Robert J. Carroll,Eulalia Catamo,John C. Chambers,Miao-Ling Chee,Miao-Li Chee,Xu Chen,Ching-Yu Cheng,Yurong Cheng,Kaare Christensen,Renata Cifkova,Marina Ciullo,Maria Pina Concas,James P. Cook,Josef Coresh,Tanguy Corre,Cinzia Sala,Daniele Cusi,John Danesh,E. Warwick Daw,Martin H. de Borst,Alessandro De Grandi,Renée de Mutsert,Aiko P. J. de Vries,Frauke Degenhardt,Graciela E. Delgado,Ayse Demirkan,Emanuele Di Angelantonio,Katalin Dittrich,Jasmin Divers,Rajkumar Dorajoo,Kai-Uwe Eckardt,Georg Ehret,Paul Elliott,Karlhans Endlich,Michele K. Evans,Janine F. Felix,Valencia Hui Xian Foo,Oscar H. Franco,Andre Franke,Barry I. Freedman,Sandra Freitag-Wolf,Yechiel Friedlander,Philippe Froguel,Ron T. Gansevoort,He Gao,Paolo Gasparini,J. Michael Gaziano,Vilmantas Giedraitis,Christian Gieger,Giorgia Girotto,Franco Giulianini,Martin Gögele,Scott D. Gordon,Daniel F. Gudbjartsson,Vilmundur Gudnason,Toomas Haller,Pavel Hamet,Tamara B. Harris,Catharina A. Hartman,Caroline Hayward,Jacklyn N. Hellwege,Chew-Kiat Heng,Andrew A. Hicks,Edith Hofer,Wei Huang,Nina Hutri-Kähönen,Shih-Jen Hwang,M. Arfan Ikram,Olafur S. Indridason,Erik Ingelsson,Marcus Ising,Vincent W. V. Jaddoe,Johanna Jakobsdottir,Jost B. Jonas,Peter K. Joshi,Navya Shilpa Josyula,Bettina Jung,Mika Kähönen,Yoichiro Kamatani,Candace M. Kammerer,Masahiro Kanai,Mika Kastarinen,Shona M. Kerr,Chiea Chuen Khor,Wieland Kiess,Marcus E. Kleber,Wolfgang Koenig,Jaspal S. Kooner,Antje Körner,Peter Kovacs,Aldi T. Kraja,Alena Krajčoviechová,Holly Kramer,Bernhard K. Krämer,Florian Kronenberg,Michiaki Kubo,Brigitte Kühnel,Mikko Kuokkanen,Johanna Kuusisto,Martina La Bianca,Markku Laakso,Leslie A. Lange,Carl D. Langefeld,Jeannette Lee,Benjamin Lehne,Terho Lehtimäki,Wolfgang Lieb,Su Chi Lim,Lars Lind,Cecilia M. Lindgren,Jun Liu,Jianjun Liu,Markus Loeffler,Ruth J. F. Loos,Susanne Lucae,Mary Ann Lukas,Leo-Pekka Lyytikäinen,Reedik Mägi,Patrik K. E. Magnusson,Anubha Mahajan,Nicholas G. Martin,Jade Martins,Winfried März,Deborah Mascalzoni,Koichi Matsuda,Christa Meisinger,Thomas Meitinger,Olle Melander,Andres Metspalu,Evgenia K. Mikaelsdottir,Yuri Milaneschi,Kozeta Miliku,Pashupati P. Mishra,VA Million Veteran Program,Karen L. Mohlke,Nina Mononen,Grant W. Montgomery,Dennis O. Mook-Kanamori,Josyf C. Mychaleckyj,Girish N. Nadkarni,Mike A. Nalls,Matthias Nauck,Kjell Nikus,Boting Ning,Ilja M. Nolte,Raymond Noordam,Jeffrey R. O'Connell,Michelle L. O'Donoghue,Isleifur Olafsson,Albertine J. Oldehinkel,Marju Orho-Melander,Willem H. Ouwehand,Sandosh Padmanabhan,Nicholette D. Palmer,Runolfur Palsson,Brenda W.J.H. Penninx,Thomas T. Perls,Markus Perola,Mario Pirastu,Nicola Pirastu,Giorgio Pistis,Anna I. Podgornaia,Ozren Polasek,Belen Ponte,David J. Porteous,Tanja Poulain,Peter P. Pramstaller,Michael Preuss,Bram P. Prins,Michael A. Province,Ton J. Rabelink,Laura M. Raffield,Olli T. Raitakari,Dermot F. Reilly,Rainer Rettig,Myriam Rheinberger,Kenneth Rice,Paul M. Ridker,Fernando Rivadeneira,Federica Rizzi,David J. Roberts,Antonietta Robino,Peter Rossing,Igor Rudan,Rico Rueedi,Daniela Ruggiero,Kathleen A. Ryan,Yasaman Saba,Charumathi Sabanayagam,Veikko Salomaa,Erika Salvi,Kai-Uwe Saum,Helena Schmidt,Reinhold Schmidt,Ben Schöttker,Christina-Alexandra Schulz,Nicole Schupf,Christian M. Shaffer,Yuan Shi,Albert V. Smith,Blair H. Smith,Nicole Soranzo,Cassandra N. Spracklen,Konstantin Strauch,Heather M. Stringham,Michael Stumvoll,Per Svensson,Silke Szymczak,E-Shyong Tai,Salman M. Tajuddin,Nicholas Y. Q. Tan,Kent D. Taylor,Andrej Teren,Yih Chung Tham,Joachim Thiery,Chris H. L. Thio,Hauke Thomsen,Gudmar Thorleifsson,Daniela Toniolo,Anke Tönjes,Johanne Tremblay,Ioanna Tzoulaki,André G. Uitterlinden,Simona Vaccargiu,Rob M. van Dam,Pim van der Harst,Cornelia M. van Duijn,Digna R. Velez Edward,Niek Verweij,Suzanne Vogelezang,Uwe Völker,Peter Vollenweider,Gérard Waeber,Melanie Waldenberger,Lars Wallentin,Ya Xing Wang,Chaolong Wang,Dawn M. Waterworth,Wen Bin Wei,Harvey D. White,John Whitfield,Sarah H. Wild,James F. Wilson,Mary K. Wojczynski,Charlene A. Wong,Tien Yin Wong,Liang Xu,Qiong Yang,Masayuki Yasuda,Laura M. Yerges-Armstrong,Weihua Zhang,Alan B. Zonderman,Jerome I. Rotter,Murielle Bochud,Bruce M. Psaty,Veronique Vitart,James G. Wilson,Abbas Dehghan,Afshin Parsa,Daniel I. Chasman,Kevin Ho,Andrew P. Morris,Olivier Devuyst,Shreeram Akilesh,Sarah A. Pendergrass,Xueling Sim,Carsten A. Böger,Yukinori Okada,Todd L. Edwards,Harold Snieder,Kari Stefansson,Adriana M. Hung,Iris M. Heid,Markus Scholz,Alexander Teumer,Anna Köttgen,Cristian Pattaro +327 more
TL;DR: Trans-ancestry meta-analysis of estimated glomerular filtration rate (eGFR) from 1,046,070 individuals identifies 264 associated loci, providing a resource of molecular targets for translational research of chronic kidney disease.
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
Gail Davies,Max Lam,Sarah E. Harris,Joey W. Trampush,Michelle Luciano,W. David Hill,Saskia P. Hagenaars,Stuart J. Ritchie,Riccardo E. Marioni,Chloe Fawns-Ritchie,David C. Liewald,Judith A. Okely,Ari Ahola-Olli,Catriona L. K. Barnes,Lars Bertram,Joshua C. Bis,Katherine E. Burdick,Andrea Christoforou,Pamela DeRosse,Srdjan Djurovic,Thomas Espeseth,Stella G. Giakoumaki,Sudheer Giddaluru,Daniel E. Gustavson,Caroline Hayward,Edith Hofer,M. Arfan Ikram,Robert Karlsson,Emma Knowles,Jari Lahti,Markus Leber,Shuo Li,Karen A. Mather,Ingrid Melle,Derek W. Morris,Christopher Oldmeadow,Teemu Palviainen,Antony Payton,Raha Pazoki,K. Petrovic,Chandra A. Reynolds,Muralidharan Sargurupremraj,Markus Scholz,Jennifer A. Smith,Albert V. Smith,Natalie Terzikhan,Anbupalam Thalamuthu,Stella Trompet,Sven J. van der Lee,Erin B. Ware,B. Gwen Windham,Margaret J. Wright,Jingyun Yang,Jin Yu,David Ames,Najaf Amin,Philippe Amouyel,Ole A. Andreassen,Nicola J. Armstrong,Amelia A. Assareh,John Attia,Deborah K. Attix,Dimitrios Avramopoulos,David A. Bennett,Anne C. Boehmer,Patricia A. Boyle,Henry Brodaty,Harry Campbell,Tyrone D. Cannon,Elizabeth T. Cirulli,Eliza Congdon,Emily Drabant Conley,Janie Corley,Simon R. Cox,Anders M. Dale,Abbas Dehghan,Danielle M. Dick,Dwight Dickinson,Johan G. Eriksson,Evangelos Evangelou,Jessica D. Faul,Ian Ford,Nelson A. Freimer,He Gao,Ina Giegling,Nathan A. Gillespie,Scott D. Gordon,Rebecca F. Gottesman,Michael Griswold,Vilmundur Gudnason,Tamara B. Harris,Annette M. Hartmann,Alex Hatzimanolis,Gerardo Heiss,Elizabeth G. Holliday,Peter K. Joshi,Mika Kähönen,Sharon L.R. Kardia,Ida K. Karlsson,Luca Kleineidam,David S. Knopman,Nicole A. Kochan,Bettina Konte,John B.J. Kwok,Stephanie Le Hellard,Teresa Lee,Terho Lehtimäki,Shu-Chen Li,Tian Liu,Marisa Koini,Edythe D. London,Will Longstreth,Oscar L. Lopez,Anu Loukola,Tobias Luck,Astri J. Lundervold,Anders Lundquist,Leo-Pekka Lyytikäinen,Nicholas G. Martin,Grant W. Montgomery,Alison D. Murray,Anna C. Need,Raymond Noordam,Lars Nyberg,William E R Ollier,Goran Papenberg,Alison Pattie,Ozren Polasek,Russell A. Poldrack,Bruce M. Psaty,Simone Reppermund,Steffi G. Riedel-Heller,Richard J. Rose,Jerome I. Rotter,Panos Roussos,Suvi P. Rovio,Yasaman Saba,Fred W. Sabb,Perminder S. Sachdev,Claudia L. Satizabal,Matthias Schmid,Rodney J. Scott,Matthew A. Scult,Jeannette Simino,P. Eline Slagboom,Nikolaos Smyrnis,Aicha Soumare,Nikos C. Stefanis,David J. Stott,Richard E. Straub,Kjetil Sundet,Adele M. Taylor,Kent D. Taylor,Ioanna Tzoulaki,Christophe Tzourio,André G. Uitterlinden,Veronique Vitart,Aristotle N. Voineskos,Jaakko Kaprio,Michael Wagner,Holger Wagner,Leonie Weinhold,K. Hoyan Wen,Elisabeth Widen,Qiong Yang,Wei Zhao,Hieab H.H. Adams,Dan E. Arking,Robert M. Bilder,Panos Bitsios,Eric Boerwinkle,Ornit Chiba-Falek,Aiden Corvin,Philip L. De Jager,Stéphanie Debette,Gary Donohoe,Paul Elliott,Annette L. Fitzpatrick,Michael Gill,David C. Glahn,Sara Hägg,Narelle K. Hansell,Ahmad R. Hariri,M. Kamran Ikram,J. Wouter Jukema,Eero Vuoksimaa,Matthew C. Keller,William S. Kremen,Lenore J. Launer,Ulman Lindenberger,Aarno Palotie,Nancy L. Pedersen,Neil Pendleton,David J. Porteous,Katri Räikkönen,Olli T. Raitakari,Alfredo Ramirez,Ivar Reinvang,Igor Rudan,Dan Rujescu,Reinhold Schmidt,Helena Schmidt,Peter W. Schofield,Peter R. Schofield,John M. Starr,Vidar M. Steen,Julian N. Trollor,Steven T. Turner,Cornelia M. van Duijn,Arno Villringer,Daniel R. Weinberger,David R. Weir,James F. Wilson,Anil K. Malhotra,Andrew M. McIntosh,Catharine R. Gale,Sudha Seshadri,Thomas H. Mosley,Jan Bressler,Todd Lencz,Ian J. Deary +220 more
Journal ArticleDOI
Evidence of a Causal Relationship Between Adiponectin Levels and Insulin Sensitivity A Mendelian Randomization Study
He Gao,He Gao,Tove Fall,Rob M. van Dam,Allan Flyvbjerg,Björn Zethelius,Erik Ingelsson,Sara Hägg +7 more
TL;DR: The observed association between higher adiponectin levels and increased insulin sensitivity is likely to represent a causal relationship partly mediated by reduced adiposity, and adjustment for BMI and waist circumference partly explained the association.
Journal ArticleDOI
A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2
Ying Wu,He Gao,He Gao,Huaixing Li,Yasuharu Tabara,Masahiro Nakatochi,Yen Feng Chiu,Yen Feng Chiu,Eun Jung Park,Wanqing Wen,Linda S. Adair,Judith B. Borja,Qiuyin Cai,Yi-Cheng Chang,Yi-Cheng Chang,Peng Chen,Damien C. Croteau-Chonka,Marie P. Fogarty,Wei Gan,Chih Tsueng He,Chao A. Hsiung,Chii Min Hwu,Sahoko Ichihara,Michiya Igase,Jaeseong Jo,Norihiro Kato,Ryuichi Kawamoto,Christophor W. Kuzawa,Jeannette Lee,Jianjun Liu,Jianjun Liu,Ling Lu,Thomas W. McDade,Haruhiko Osawa,Wayne Huey-Herng Sheu,Yvonne Teo,Swarooparani Vadlamudi,Rob M. van Dam,Yiqin Wang,Yong-Bing Xiang,Ken Yamamoto,Xingwang Ye,Terri L. Young,Terri L. Young,Wei Zheng,Jingwen Zhu,Xiao-Ou Shu,Chol Shin,Sun Ha Jee,Lee-Ming Chuang,Tetsuro Miki,Mitsuhiro Yokota,Xu Lin,Karen L. Mohlke,E. Shyong Tai +54 more
TL;DR: The identification of a novel adiponectin-associated locus on chromosome 10 near WDR11-FGFR2 and the independence of two pairs of closely located loci (<2 Mb) on chromosome 16 at CMIP and CDH13, and on chromosome 12 at GPR109A and ZNF664 are confirmed.
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure
Yun J. Sung,Thomas W. Winkler,Lisa de las Fuentes,Amy R. Bentley,Michael R. Brown,Aldi T. Kraja,Karen Schwander,Ioanna Ntalla,Xiuqing Guo,Nora Franceschini,Yingchang Lu,Ching-Yu Cheng,Xueling Sim,Dina Vojinovic,Jonathan Marten,Solomon K. Musani,Changwei Li,Mary F. Feitosa,Tuomas O. Kilpeläinen,Melissa A. Richard,Raymond Noordam,Stella Aslibekyan,Hugues Aschard,Traci M. Bartz,Rajkumar Dorajoo,Yongmei Liu,Alisa K. Manning,Tuomo Rankinen,Albert V. Smith,Salman M. Tajuddin,Bamidele O. Tayo,Helen R. Warren,Wei Zhao,Yanhua Zhou,Nana Matoba,Tamar Sofer,Maris Alver,Marzyeh Amini,Mathilde Boissel,Jin-Fang Chai,Xu Chen,Jasmin Divers,Ilaria Gandin,Chuan Gao,Franco Giulianini,Anuj Goel,Sarah E. Harris,Fernando Pires Hartwig,Andrea R. V. R. Horimoto,Fang-Chi Hsu,Anne U. Jackson,Mika Kähönen,Anuradhani Kasturiratne,Brigitte Kühnel,Karin Leander,Wen-Jane Lee,Keng-Hung Lin,Jian'an Luan,Colin A. McKenzie,He Meian,Christopher P. Nelson,Rainer Rauramaa,Nicole Schupf,Robert A. Scott,Wayne Huey-Herng Sheu,Alena Stančáková,Fumihiko Takeuchi,Peter J. van der Most,Tibor V. Varga,Heming Wang,Yajuan Wang,Erin B. Ware,Stefan Weiss,Wanqing Wen,Lisa R. Yanek,Weihua Zhang,Jing Hua Zhao,Saima Afaq,Tamuno Alfred,Najaf Amin,Dan E. Arking,Tin Aung,R. Graham Barr,Lawrence F. Bielak,Eric Boerwinkle,Erwin P. Bottinger,Peter S. Braund,Jennifer A. Brody,Ulrich Broeckel,Claudia P. Cabrera,Brian E. Cade,Yu Caizheng,Archie Campbell,Mickaël Canouil,Aravinda Chakravarti,Ganesh Chauhan,Kaare Christensen,Massimiliano Cocca,Francis S. Collins,John M. C. Connell,Renée de Mutsert,H. Janaka de Silva,Stéphanie Debette,Marcus Dörr,Qing Duan,Charles B. Eaton,Georg Ehret,Evangelos Evangelou,Jessica D. Faul,Virginia Fisher,Nita G. Forouhi,Oscar H. Franco,Yechiel Friedlander,He Gao,Bruna Gigante,Misa Graff,C. Charles Gu,Dongfeng Gu,Preeti Gupta,Saskia P. Hagenaars,Tamara B. Harris,Jiang He,Sami Heikkinen,Chew-Kiat Heng,Makoto Hirata,Albert Hofman,Barbara V. Howard,Steven C. Hunt,Marguerite R. Irvin,Yucheng Jia,Roby Joehanes,Anne E. Justice,Tomohiro Katsuya,Joel D. Kaufman,Nicola D. Kerrison,Chiea Chuen Khor,Woon-Puay Koh,Heikki A. Koistinen,Pirjo Komulainen,Charles Kooperberg,José Eduardo Krieger,Michiaki Kubo,Johanna Kuusisto,Carl D. Langefeld,Claudia Langenberg,Lenore J. Launer,Benjamin Lehne,Cora E. Lewis,Yize Li,Sing Hui Lim,Shiow Lin,Ching-Ti Liu,Jianjun Liu,Jingmin Liu,Kiang Liu,Y Liu,Marie Loh,Kurt Lohman,Jirong Long,Tin Louie,Reedik Mägi,Anubha Mahajan,Thomas Meitinger,Andres Metspalu,Lili Milani,Yukihide Momozawa,Andrew P. Morris,Thomas H. Mosley,Peter J. Munson,Alison D. Murray,Mike A. Nalls,Ubaydah Nasri,Jill M. Norris,Kari E. North,Adesola Ogunniyi,Sandosh Padmanabhan,Walter Palmas,Nicholette D. Palmer,James S. Pankow,Nancy L. Pedersen,Annette Peters,Patricia A. Peyser,Ozren Polasek,Olli T. Raitakari,Frida Renström,Treva Rice,Paul M. Ridker,Antonietta Robino,Jennifer G. Robinson,Lynda M. Rose,Igor Rudan,Charumathi Sabanayagam,Babatunde L. Salako,Kevin Sandow,Carsten Oliver Schmidt,Pamela J. Schreiner,William R. Scott,Sudha Seshadri,Peter S. Sever,Colleen M. Sitlani,Jennifer A. Smith,Harold Snieder,John M. Starr,Konstantin Strauch,Hua Tang,Kent D. Taylor,Yik Ying Teo,Yih Chung Tham,Andre G. Ultterlinden,Melanie Waldenberger,Lihua Wang,Ya X. Wang,Wen Bin Wei,Christine Williams,Gregory P. Wilson,Mary K. Wojczynski,Jie Yao,Jian-Min Yuan,Alan B. Zonderman,Diane M. Becker,Michael Boehnke,Donald W. Bowden,John C. Chambers,Yii-Der Ida Chen,Ulf de Faire,Ian J. Deary,Tõnu Esko,Martin Farrall,Terrence Forrester,Paul W. Franks,Barry I. Freedman,Philippe Froguel,Paolo Gasparini,Christian Gieger,Bernardo L. Horta,Yi-Jen Hung,Jost B. Jonas,Norihiro Kato,Jaspal S. Kooner,Markku Laakso,Terho Lehtimäki,Kae-Woei Liang,Patrik K. E. Magnusson,Anne B. Newman,Albertine J. Oldehinkel,Alexandre C. Pereira,Susan Redline,Rainer Rettig,Nilesh J. Samani,James F. Scott,Xiao-Ou Shu,Pim van der Harst,Lynne E. Wagenknecht,Nicholas J. Wareham,Hugh Watkins,David R. Weir,Ananda R. Wickremasinghe,Tangchun Wu,Wei Zheng,Yoichiro Kamatani,Cathy C. Laurie,Claude Bouchard,Richard S. Cooper,Michele K. Evans,Vilmundur Gudnason,Sharon L.R. Kardia,Stephen B. Kritchevsky,Daniel Levy,Jeffrey R. O'Connell,Bruce M. Psaty,Rob M. van Dam,Mario Sims,Donna K. Arnett,Dennis O. Mook-Kanamori,Tanika N. Kelly,Ervin R. Fox,Caroline Hayward,Myriam Fornage,Charles N. Rotimi,Michael A. Province,Cornelia M. van Duijn,E. Shyong Tai,Tien Yin Wong,Ruth J. F. Loos,Alexander P. Reiner,Jerome I. Rotter,Xiaofeng Zhu,Laura J. Bierut,W. James Gauderman,Mark J. Caulfield,Paul Elliott,Kenneth Rice,Patricia B. Munroe,Alanna C. Morrison,L. Adrienne Cupples,Dabeeru C. Rao,Daniel I. Chasman +296 more
TL;DR: In this article, the authors performed genome-wide association meta-analyses of systolic and diastolic BP incorporating gene-smoking interactions in 610,091 individuals.