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Institution

Aix-Marseille University

EducationMarseille, France
About: Aix-Marseille University is a education organization based out in Marseille, France. It is known for research contribution in the topics: Population & Galaxy. The organization has 24326 authors who have published 54240 publications receiving 1455416 citations. The organization is also known as: University Aix-Marseille & université d'Aix-Marseille.


Papers
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Journal ArticleDOI
TL;DR: In this article, the authors examined how the intestinal environment affects microbial genome evolution and found that lateral gene transfer, mobile elements, and gene amplification have played important roles in affecting the ability of gut-dwelling Bacteroidetes to vary their cell surface, sense their environment, and harvest nutrient resources present in the distal intestine.
Abstract: The adult human intestine contains trillions of bacteria, representing hundreds of species and thousands of subspecies. Little is known about the selective pressures that have shaped and are shaping this community's component species, which are dominated by members of the Bacteroidetes and Firmicutes divisions. To examine how the intestinal environment affects microbial genome evolution, we have sequenced the genomes of two members of the normal distal human gut microbiota, Bacteroides vulgatus and Bacteroides distasonis, and by comparison with the few other sequenced gut and non-gut Bacteroidetes, analyzed their niche and habitat adaptations. The results show that lateral gene transfer, mobile elements, and gene amplification have played important roles in affecting the ability of gut-dwelling Bacteroidetes to vary their cell surface, sense their environment, and harvest nutrient resources present in the distal intestine. Our findings show that these processes have been a driving force in the adaptation of Bacteroidetes to the distal gut environment, and emphasize the importance of considering the evolution of humans from an additional perspective, namely the evolution of our microbiomes.

558 citations

Journal ArticleDOI
TL;DR: The first example of ordered hexagonal covalent nanoporous structures deposited in extended arrays of near monolayer coverage across a Ag(111) surface is presented.
Abstract: The development of nanoscale masking for particle deposition is exceedingly important to push the future of nanoelectronics beyond the current limits of lithography We present the first example of ordered hexagonal covalent nanoporous structures deposited in extended arrays of near monolayer coverage across a Ag(111) surface The networks were formed from the deposition of the reagents from a heated molybdenum crucible between 370 and 460 K under ultrahigh vacuum (UHV) onto a cleaned Ag(111) substrate and imaged using a scanning tunneling microscope (STM) Two surface covalent organic frameworks (SCOFs) are presented; the first is formed from the deposition of 1,4-benzenediboronic acid (BDBA) and its dehydration to form the boroxine-linked SCOF-1, the second is formed from the co-deposition of BDBA and 2,3,6,7,10,11-hexahydroxytriphenylene (HHTP) to form a dioxaborole-linked SCOF-2 network The networks were found to produce nanoporous structures of 15 A for SCOF-1 and 29 A for SCOF-2, which agreed with

557 citations

Journal ArticleDOI
TL;DR: In this article, the authors report world averages of measurements of b-hadron, c-, c-, and tau-lepton properties obtained by the Heavy Flavor Averaging Group (HFAG) using results available through the end of 2011.
Abstract: This article reports world averages of measurements of b-hadron, c-hadron, and tau-lepton properties obtained by the Heavy Flavor Averaging Group (HFAG) using results available through the end of 2011. In some cases results available in the early part of 2012 are included. For the averaging, common input parameters used in the various analyses are adjusted (rescaled) to common values, and known correlations are taken into account. The averages include branching fractions, lifetimes, neutral meson mixing parameters, CP violation parameters, parameters of semileptonic decays and CKM matrix elements.

554 citations

Journal ArticleDOI
TL;DR: It is not possible to assess the risks associated with the use of ENM by investigating only the pristine form of the ENM, without considering alterations and transformation processes, and a more definitive classification scheme for ENM should be adopted.
Abstract: The risks associated with exposure to engineered nanomaterials (ENM) will be determined in part by the processes that control their environmental fate and transformation. These processes act not only on ENM that might be released directly into the environment, but more importantly also on ENM in consumer products and those that have been released from the product. The environmental fate and transformation are likely to differ significantly for each of these cases. The ENM released from actual direct use or from nanomaterial-containing products are much more relevant for ecotoxicological studies and risk assessment than pristine ENM. Released ENM may have a greater or lesser environmental impact than the starting materials, depending on the transformation reactions and the material. Almost nothing is known about the environmental behavior and the effects of released and transformed ENM, although these are the materials that are actually present in the environment. Further research is needed to determine whether the release and transformation processes result in a similar or more diverse set of ENM and ultimately how this affects environmental behavior. This article addresses these questions, using four hypothetical case studies that cover a wide range of ENM, their direct use or product applications, and their likely fate in the environment. Furthermore, a more definitive classification scheme for ENM should be adopted that reflects their surface condition, which is a result of both industrial and environmental processes acting on the ENM. The authors conclude that it is not possible to assess the risks associated with the use of ENM by investigating only the pristine form of the ENM, without considering alterations and transformation processes. Environ. Toxicol. Chem. 2012;31:5059. (C) 2011 SETAC

552 citations

Journal ArticleDOI
21 Feb 2013-Immunity
TL;DR: It is concluded that inflammatory DCs represent a distinct human DC subset and proposed that they are derived from monocytes and are involved in the induction and maintenance of Th17 cell responses.

550 citations


Authors

Showing all 24784 results

NameH-indexPapersCitations
Didier Raoult1733267153016
Andrea Bocci1722402176461
Marc Humbert1491184100577
Carlo Rovelli1461502103550
Marc Besancon1431799106869
Jian Yang1421818111166
Josh Moss139101989255
Maksym Titov1391573128335
Bernard Henrissat139593100002
R. D. Kass1381920107907
Stylianos E. Antonarakis13874693605
Jean-Paul Kneib13880589287
Brad Abbott137156698604
Shu Li136100178390
Georges Aad135112188811
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023170
2022748
20215,607
20205,697
20195,288
20185,125