Institution
Southwest University
Education•Chongqing, China•
About: Southwest University is a education organization based out in Chongqing, China. It is known for research contribution in the topics: Gene & Population. The organization has 29772 authors who have published 27755 publications receiving 409441 citations. The organization is also known as: Southwest University in Chongqing & SWU.
Topics: Gene, Population, Catalysis, Bombyx mori, Adsorption
Papers published on a yearly basis
Papers
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TL;DR: In this paper, a colloquium is devoted to evolutionary games on multilayer networks, and in particular to the evolution of cooperation as one of the main pillars of modern human societies.
Abstract: Networks form the backbone of many complex systems, ranging from the Internet to human societies. Accordingly, not only is the range of our interactions limited and thus best described and modeled by networks, it is also a fact that the networks that are an integral part of such models are often interdependent or even interconnected. Networks of networks or multilayer networks are therefore a more apt description of social systems. This colloquium is devoted to evolutionary games on multilayer networks, and in particular to the evolution of cooperation as one of the main pillars of modern human societies. We first give an overview of the most significant conceptual differences between single-layer and multilayer networks, and we provide basic definitions and a classification of the most commonly used terms. Subsequently, we review fascinating and counterintuitive evolutionary outcomes that emerge due to different types of interdependencies between otherwise independent populations. The focus is on coupling through the utilities of players, through the flow of information, as well as through the popularity of different strategies on different network layers. The colloquium highlights the importance of pattern formation and collective behavior for the promotion of cooperation under adverse conditions, as well as the synergies between network science and evolutionary game theory.
603 citations
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TL;DR: In this article, a meta-analysis aimed to review the relationship between trait resilience and mental health, and examine some moderating variables such as participant age, gender, and adversity.
603 citations
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Commonwealth Scientific and Industrial Research Organisation1, McGill University2, Goddard Space Flight Center3, University of California, Berkeley4, Swinburne University of Technology5, University of Cagliari6, Australia Telescope National Facility7, Max Planck Society8, University of California, San Diego9, Cornell University10, National Radio Astronomy Observatory11, Pennsylvania State University12, University of British Columbia13, University of Amsterdam14, Curtin University15, University of Manchester16, University of Texas at Brownsville17, West Virginia University18, United States Naval Research Laboratory19, Peking University20, Leiden University21, Franklin & Marshall College22, University of Virginia23, Bryn Mawr College24, University of Wisconsin–Milwaukee25, Oberlin College26, University of Sydney27, Southwest University28
TL;DR: The International Pulsar Timing Array (IPTA) project as mentioned in this paper combines observations of pulsars from both northern and southern hemisphere observatories with the main aim of detecting ultra-low frequency (similar to 10(-9)-10(-8) Hz) gravitational waves.
Abstract: The International Pulsar Timing Array project combines observations of pulsars from both northern and southern hemisphere observatories with the main aim of detecting ultra-low frequency (similar to 10(-9)-10(-8) Hz) gravitational waves. Here we introduce the project, review the methods used to search for gravitational waves emitted from coalescing supermassive binary black-hole systems in the centres of merging galaxies and discuss the status of the project.
583 citations
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TL;DR: W Whole-genome analyses indicate that the genome structures of these two species are highly syntenic and suggest that the genus Metarhizium evolved from plant endophytes or pathogens, andTranscriptional analysis of both fungi during early infection processes provided further insights into the genes and pathways involved in infectivity and specificity.
Abstract: Metarhizium spp. are being used as environmentally friendly alternatives to chemical insecticides, as model systems for studying insect-fungus interactions, and as a resource of genes for biotechnology. We present a comparative analysis of the genome sequences of the broad-spectrum insect pathogen Metarhizium anisopliae and the acridid-specific M. acridum. Whole-genome analyses indicate that the genome structures of these two species are highly syntenic and suggest that the genus Metarhizium evolved from plant endophytes or pathogens. Both M. anisopliae and M. acridum have a strikingly larger proportion of genes encoding secreted proteins than other fungi, while ∼30% of these have no functionally characterized homologs, suggesting hitherto unsuspected interactions between fungal pathogens and insects. The analysis of transposase genes provided evidence of repeat-induced point mutations occurring in M. acridum but not in M. anisopliae. With the help of pathogen-host interaction gene database, ∼16% of Metarhizium genes were identified that are similar to experimentally verified genes involved in pathogenicity in other fungi, particularly plant pathogens. However, relative to M. acridum, M. anisopliae has evolved with many expanded gene families of proteases, chitinases, cytochrome P450s, polyketide synthases, and nonribosomal peptide synthetases for cuticle-degradation, detoxification, and toxin biosynthesis that may facilitate its ability to adapt to heterogenous environments. Transcriptional analysis of both fungi during early infection processes provided further insights into the genes and pathways involved in infectivity and specificity. Of particular note, M. acridum transcribed distinct G-protein coupled receptors on cuticles from locusts (the natural hosts) and cockroaches, whereas M. anisopliae transcribed the same receptor on both hosts. This study will facilitate the identification of virulence genes and the development of improved biocontrol strains with customized properties.
575 citations
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TL;DR: This work systematically gives a comprehensive review in current developments of imidazole‐based compounds in the whole range of medicinal chemistry as anticancer, antifungal, antibacterial, antitubercular, anti‐inflammatory, antineuropathic, antihypertensive, antihistaminic, antiparasitic, antiobesity, antiviral, and other medicinal agents, together with their potential applications in diagnostics and pathology.
Abstract: Imidazole ring is an important five-membered aromatic heterocycle widely present in natural products and synthetic molecules. The unique structural feature of imidazole ring with desirable electron-rich characteristic is beneficial for imidazole derivatives to readily bind with a variety of enzymes and receptors in biological systems through diverse weak interactions, thereby exhibiting broad bioactivities. The related research and developments of imidazole-based medicinal chemistry have become a rapidly developing and increasingly active topic. Particularly, numerous imidazole-based compounds as clinical drugs have been extensively used in the clinic to treat various types of diseases with high therapeutic potency, which have shown the enormous development value. This work systematically gives a comprehensive review in current developments of imidazole-based compounds in the whole range of medicinal chemistry as anticancer, antifungal, antibacterial, antitubercular, anti-inflammatory, antineuropathic, antihypertensive, antihistaminic, antiparasitic, antiobesity, antiviral, and other medicinal agents, together with their potential applications in diagnostics and pathology. It is hoped that this review will be helpful for new thoughts in the quest for rational designs of more active and less toxic imidazole-based medicinal drugs, as well as more effective diagnostic agents and pathologic probes.
558 citations
Authors
Showing all 29978 results
Name | H-index | Papers | Citations |
---|---|---|---|
Frank B. Hu | 250 | 1675 | 253464 |
Hongjie Dai | 197 | 570 | 182579 |
Jing Wang | 184 | 4046 | 202769 |
Chao Zhang | 127 | 3119 | 84711 |
Jianjun Liu | 112 | 1040 | 71032 |
Miao Liu | 111 | 993 | 59811 |
Jun Yang | 107 | 2090 | 55257 |
Eric Westhof | 98 | 472 | 34825 |
En-Tang Kang | 97 | 763 | 38498 |
Chang Ming Li | 97 | 896 | 42888 |
Wei Zhou | 93 | 1640 | 39772 |
Li Zhang | 92 | 918 | 35648 |
Heinz Rennenberg | 87 | 527 | 26359 |
Tao Chen | 86 | 820 | 27714 |
Xun Wang | 84 | 606 | 32187 |