University of Colorado Colorado Springs

About: University of Colorado Colorado Springs is a education organization based out in Colorado Springs, Colorado, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 6664 authors who have published 10872 publications receiving 323416 citations. The organization is also known as: UCCS & University of Colorado at Colorado Springs.

Effect of hypoxic "dose" on physiological responses and sea-level performance.

Abstract: Live high-train low (LH+TL) altitude training was developed in the early 1990s in response to potential training limitations imposed on endurance athletes by traditional live high-train high (LH+TH) altitude training. The essence of LH+TL is that it allows athletes to "live high" for the purpose of facilitating altitude acclimatization, as manifest by a profound and sustained increase in endogenous erythropoietin (EPO) and ultimately an augmented erythrocyte volume, while simultaneously allowing athletes to "train low" for the purpose of replicating sea-level training intensity and oxygen flux, thereby inducing beneficial metabolic and neuromuscular adaptations. In addition to "natural/terrestrial" LH+TL, several simulated LH+TL devices have been developed to conveniently bring the mountain to the athlete, including nitrogen apartments, hypoxic tents, and hypoxicator devices. One of the key questions regarding the practical application of LH+TL is, what is the optimal hypoxic dose needed to facilitate altitude acclimatization and produce the expected beneficial physiological responses and sea-level performance effects? The purpose of this paper is to objectively answer that question, on the basis of an extensive body of research by our group in LH+TL altitude training. We will address three key questions: 1) What is the optimal altitude at which to live? 2) How many days are required at altitude? and 3) How many hours per day are required? On the basis of consistent findings from our research group, we recommend that for athletes to derive the physiological benefits of LH+TL, they need to live at a natural elevation of 2000-2500 m for >or=4 wk for >or=22 h.d(-1).

Perceived Racist Discrimination, Coping, Stress, and Life Satisfaction.

Abstract: In this study, avoidance coping and problem-solving coping (inversely) predicted stress, and stress and avoidance coping inversely predicted life satisfaction among 114 African American students. Coping did not moderate racial discrimination stress or stress-life satisfaction relationships. Fostering problem solving and reducing avoidance may help to alleviate racism-related stress and foster well-being. En este estudio, evitar sobrellevar y sobrellevar la resolucion de problemas (a lo inverso) de estres predicho, estres, y el evitar sobrellevar a la inversa predicha de la satisfaccion de vida, entre 114 estudiantes Afro-Americanos. El sobrellevar no modero el estres de la discriminacion racial ni relaciones de satisfaccion en el estres de vida. Fomentar la resolucion del problema y reducir el evitar puede ayudar a aliviar el estres relacionado al racismo y fomentar el bienestar.

Religious Preference and Practice: Reevaluating Their Impact on Political Tolerance

Abstract: ALTHOUGH surveys conducted in the 1960s and 70s have produced evidence of the public's increasing political tolerance, some scholars have questioned those findings and the methods that produced them. At the same time, visible political action by religious groups and their leaders has created renewed interest in the connections between religious beliefs and practice on the one hand and political beliefs and actions on the other. These two areas of study-political tolerance and religion-are not unrelated. Political tolerance has long been linked to religion, but that linkage has been defined only vaguely. We explore the relationship, examining both religious denomination and church attendance as correlates of political tolerance. This investigation differs from prior studies in looking at political tolerance within rather precise denominational groups and by evaluating the effects of church attendance within denominations. Our findings shed light on the nature and sources of political tolerance, while also suggesting

Amantadine in a Multimodal Analgesic Regimen for Alleviation of Refractory Osteoarthritis Pain in Dogs

Abstract: Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) do not always provide sufficient pain relief in dogs with osteoarthritis (OA). Hypothesis: The use of amantadine in addition to NSAID therapy will provide improved pain relief when compared with the use of nonsteroidal analgesics alone in naturally occurring OA in dogs. Animals: Thirty-one client-owned dogs with pelvic limb lameness despite the administration of an NSAID. Methods: The study was randomized, blinded, and placebo controlled with parallel groups (days 21–42). On day 0, analgesic medications were discontinued. On day 7, all dogs received meloxicam for 5 weeks. On day 21, all dogs received amantadine (3–5 mg/kg once daily per os) or placebo for 21 days, in addition to receiving meloxicam. Assessments were performed before the study and on days 7, 21, and 42. Primary outcome measures were blinded owner assessments of activity using client-specific outcome measures (CSOM) on days 0, 7, 21, and 42. Data were analyzed by a mixed model approach. Results: For CSOM activity, there was a significant time by treatment effect (P=.009). On the basis of the planned post hoc t-tests of postrandomization means, there was a significant difference between treatment groups on day 42 (P=.030), with the amantadine group being more active. Conclusions and Clinical Importance: In dogs with osteoarthritic pain refractory to an NSAID, physical activity is improved by the addition of amantadine. Amantadine might be a useful adjunct therapy for the clinical management of canine osteoarthritic pain.