University of Colorado Colorado Springs

About: University of Colorado Colorado Springs is a education organization based out in Colorado Springs, Colorado, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 6664 authors who have published 10872 publications receiving 323416 citations. The organization is also known as: UCCS & University of Colorado at Colorado Springs.

Maximum strength-power-performance relationships in collegiate throwers.

Abstract: Presently the degree to which peak force influences power production or explosive performance such as strength training movements or throwing (shot-put and weight-throw) is unclear. This study describes the relationships between a measure of maximum strength, isometric peak force (IPF), dynamic peak force (PF), peak power (PP), the 1-repetition movement power snatch (SN), and throwing ability over an 8-week training period. Five male and 6 female (n 5 11) well-trained collegiate throwers participated. PF was measured using an AMTI force plate; PP was measured using an infrared-ultrasonic tracking device (V-Scope, Lipman Electronics). Clean pulls from the midthigh position were assessed isometrically and dynamically at a constant load, 30% and 60% of IPF. Specific explosive strength was evaluated using an SN and using the shot-put (SP) and weightthrow (WGT) measured under meet conditions. Variables (PF, PP, SN) were assessed 3 times at 0 weeks, 4 weeks, and 8 weeks. Each measurement period preceded a field meet by 3 days. Peak force, peak rate of force development, and PP increased over the 8 weeks. Correlation coefficients (r) indicate that IPF is strongly related to dynamic PF and PP 30%, 60% of the IPF. Furthermore, strong correlations were found for the SN and the distance for the SP and WGT, and these relationships tended to increase over time. Results suggest that maximum strength (i.e., IPF) is strongly associated with dynamic PF. In addition, maximum strength is strongly associated with PP even at relatively light loads such as those associated with sport-specific dynamic explosiveness (i.e., SN, SP, WGT).

Incidence of exercise-induced bronchospasm in Olympic winter sport athletes.

Abstract: WILBER, R. L., K. W. RUNDELL, L. SZMEDRA, D. M. JENKINSON, J. IM, and S. D. DRAKE. Incidence of exercise-induced bronchospasm in Olympic winter sport athletes. Med. Sci. Sports Exerc., Vol. 32, No. 4, pp. 732‐737, 2000. Purpose: The purpose of this project was to determine the incidence of exercise-induced bronchospasm (EIB) among U.S. Olympic winter sport athletes. Methods: Subjects included female and male members of the 1998 U.S. Winter Olympic Team from the following sports: biathlon, cross-country ski, figure skating, ice hockey, Nordic combined, long-track speedskating, and short-track speedskating. Assessment of EIB was conducted in conjunction with an “actual competition” (Olympic Trials, World Team Trials, World Cup Event, U.S. National Championships) or a “simulated competition” (time trial, game), which served as the exercise challenge. Standard spirometry tests were performed preexercise and at 5, 10, and 15 min postexercise. An athlete was considered EIB-positive based on a postexercise decrement in FEV1 $ 10%. Results: For the seven sports evaluated on the 1998 U.S. Winter Olympic Team, the overall incidence of EIB across all sports and genders was 23%. The highest incidence of EIB was found in cross-country skiers, where 50% of the athletes (female 5 57%; male 5 43%) were diagnosed with EIB. Across the seven sports evaluated, the prevalence of EIB among the female and male athletes was 26% and 18%, respectively. Among those individuals found to be EIB-positive were athletes who won a team gold medal, one individual silver medal, and one individual bronze medal at the Nagano Winter Olympics. Conclusions: These data suggest that: 1) EIB is prevalent in several Olympic winter sports and affects nearly one of every four elite winter sport athletes; 2) the winter sport with the highest incidence of EIB is cross-country skiing; 3) in general, EIB is more prevalent in female versus male elite winter sport

Proximal and Distal Defenses in Response to Reminders of One’s Mortality: Evidence of a Temporal Sequence

Abstract: The present study was designed to build on prior terror management research by testing the hypothesis that death-related thought first activates direct defenses to minimize the threat (proximal defense) and then later triggers symbolic cultural worldview defense (distal defense). After mortality salience, participants were either distracted from death-related thought or not and then completed either a measure of distal defense and then a measure of proximal defense or a proximal defense measure and then a distal defense measure. Results supported the authors’ predictions. Proximal defense in the form of vulnerability denial emerged only when participants had immediately before been thinking about death. In contrast, distal defense only emerged when participants were previously distracted from death-related thought. Discussion focuses on implications of these results for understanding the sequence of defenses initiated by mortality salience.

Alternatively Activated Macrophages and Collagen Remodeling Characterize the Postpartum Involuting Mammary Gland across Species

Abstract: Recent pregnancy correlates with decreased survival for breast cancer patients compared with non–pregnancy-associated breast cancer. We hypothesize that postpartum mammary involution induces metastasis through wound-healing programs known to promote cancer. It is unknown whether alternatively activated M2 macrophages, immune cells important in wound-healing and experimental tumorigenesis that also predict poor prognosis for breast cancer patients, are recruited to the normal involuting gland. Macrophage markers CD68, CSF-1R, and F4/80 were examined across the pregnancy and involution cycle in rodent and human mammary tissues. Quantitative immunohistochemistry revealed up to an eightfold increase in macrophage number during involution, which returned to nulliparous levels with full regression. The involution macrophages exhibit an M2 phenotype as determined by high arginase-1 and low inducible nitric oxide synthase staining in rodent tissue, and by mannose receptor expression in human breast tissue. M2 cytokines IL-4 and IL-13 also peaked during involution. Extracellular matrix (ECM) isolated from involuting rat mammary glands was chemotactic for macrophages compared with nulliparous mammary ECM. Fibrillar collagen levels and proteolysis increased dramatically during involution, and denatured collagen I acted as a strong chemoattractant for macrophages in cell culture, suggesting proteolyzed fibrillar collagen as a candidate ECM mediator of macrophage recruitment. M2 macrophages, IL-4, IL-13, fibrillar collagen accumulation, and proteolysis of collagen are all components of tumor promotional microenvironments, and thus may mediate promotion of breast cancers arising in the postpartum setting.