University of Crete

About: University of Crete is a education organization based out in Rethymno, Greece. It is known for research contribution in the topics: Population & Galaxy. The organization has 8681 authors who have published 21684 publications receiving 709078 citations. The organization is also known as: Panepistimio Kritis.

GOODS-HERSCHEL: STAR FORMATION, DUST ATTENUATION, AND THE FIR–RADIO CORRELATION ON THE MAIN SEQUENCE OF STAR-FORMING GALAXIES UP TO z ≃ 4*

Abstract: We use the deep panchromatic dataset available in the GOODS-N field, spanning all the way from GALEX ultra-violet to VLA radio continuum data, to select a star-forming galaxy sample at z~[0.5-4] and robustly measure galaxy photometric redshifts, star formation rates, stellar masses and UV rest-frame properties. We quantitatively explore, using mass-complete samples, the evolution of the star formation activity and dust attenuation properties of star-forming galaxies up to z~4. Our main results can be summarized as follows: i) we find that the slope of the SFR-M correlation is consistent with being constant, and equal to ~0.8 at least up to z~1.5, while the normalization keeps increasing to the highest redshift, z~4, we are able to explore; ii) for the first time in this work, we are able to explore the FIR-radio correlation for a mass-selected sample of star-forming galaxies: the correlation does not evolve up to z~4; iii) we confirm that galaxy stellar mass is a robust proxy for UV dust attenuation in star-forming galaxies, with more massive galaxies being more dust attenuated; iv) strikingly, we find that this attenuation relation evolves very weakly with redshift, the amount of dust attenuation increasing by less than 0.3 magnitudes over the redshift range [0.5-4] for a fixed stellar mass, as opposed to a tenfold increase of star formation rate; v) this finding explains the evolution of the SFR-Auv relation reported in literature: the same amount of star formation is less attenuated at higher redshift because it is hosted in less massive, and less metal rich, galaxies; vi) the correlation between dust attenuation and the UV spectral slope evolves in redshift, with the median UV spectral slope of star-forming galaxies becoming bluer with redshift. By z~3, typical UV slopes are inconsistent, given the measured dust attenuation, with the predictions of commonly used empirical laws: this means that the present cosmic star formation rate density estimates at redshift z > 3 need to be increased by a factor of around 2. Finally, building on the measured AUV–logM correlation and on existing results, we find evidence that line reddening is marginally larger (by a factor of around 1.3) than continuum reddening at all redshifts probed, and also that the amount of dust attenuation at a fixed ISM metallicity increases with redshift. We speculate that our results point toward an evolution of the ISM conditions of the median star-forming galaxy, such that at z >1.5, Main Sequence galaxies have ISM properties more similar to those found in local starbursts.

Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence

Abstract: The selection of pharmacotherapy for patients with allergic rhinitis aims to control the disease and depends on many factors. Grading of Recommendations Assessment, Development and Evaluation (GRADE) guidelines have considerably improved the treatment of allergic rhinitis. However, there is an increasing trend toward use of real-world evidence to inform clinical practice, especially because randomized controlled trials are often limited with regard to the applicability of results. The Contre les Maladies Chroniques pour un Vieillissement Actif (MACVIA) algorithm has proposed an allergic rhinitis treatment by a consensus group. This simple algorithm can be used to step up or step down allergic rhinitis treatment. Next-generation guidelines for the pharmacologic treatment of allergic rhinitis were developed by using existing GRADE-based guidelines for the disease, real-world evidence provided by mobile technology, and additive studies (allergen chamber studies) to refine the MACVIA algorithm.

GOALS: The Great Observatories All-Sky LIRG Survey

Abstract: The Great Observatories All-sky LIRG Survey (GOALS) combines data from NASA's Spitzer, Chandra, Hubble and GALEX observatories, together with ground-based data into a comprehensive imaging and spectroscopic survey of over 200 low redshift Luminous Infrared Galaxies (LIRGs). The LIRGs are a complete subset of the IRAS Revised Bright Galaxy Sample (RBGS). The LIRGs targeted in GOALS span the full range of nuclear spectral types defined via traditional optical line-ratio diagrams as well as interaction stages. They provide an unbiased picture of the processes responsible for enhanced infrared emission in galaxies in the local Universe. As an example of the analytic power of the multi-wavelength GOALS dataset, we present data for the interacting system VV 340 (IRAS F14547+2449). Between 80-95% of the total far-infrared emission (or about 5E11 solar luminosities) originates in VV 340 North. While the IRAC colors of VV 340 North and South are consistent with star-forming galaxies, both the Spitzer IRS and Chandra ACIS data indicate the presence of a buried AGN in VV 340 North. The GALEX far and near-UV fluxes imply a extremely large infrared "excess" (IRX) for the system (IR/FUV = 81) which is well above the correlation seen in starburst galaxies. Most of this excess is driven by VV 340 N, which alone has an IR excess of nearly 400. The VV 340 system seems to be comprised of two very different galaxies - an infrared luminous edge-on galaxy (VV 340 North) that dominates the long-wavelength emission from the system and which hosts a buried AGN, and a face-on starburst (VV 340 South) that dominates the short-wavelength emission.

Wine antioxidant polyphenols inhibit the proliferation of human prostate cancer cell lines.

Abstract: The effect of different wine antioxidant polyphenols (catechin, epicatechin, quercetin, and resveratrol) on the growth of three prostate cancer cell lines (LNCaP, PC3, and DU145) was investigated. A dose- and time-dependent inhibition of cell growth by polyphenols was found at nanomolar concentrations. The proliferation of LNCaP and PC3 cells was preferentially inhibited by flavonoids (catechin, epicatechin, and quercetin), whereas resveratrol was the most potent inhibitor of DU145 cell growth. Possible mechanisms of action were investigated: 1) The competition of polyphenols for androgen binding in LNCaP cells revealed significant interaction only in the case of high concentrations of quercetin, at least at five orders of magnitude higher than the concentrations needed for cell growth inhibition. All other phenols showed low interactions. 2) Oxygen species production after mitogen stimulation and H2O2 sensitivity of these cell lines did not correlate with the observed antiproliferative effects, ruling out such a mode of action. 3) NO production revealed two different patterns: LNCaP and DU145 cells produced high concentrations of NO, whereas PC3 cells produced low concentrations. Phorbol ester stimulation of cells did not reveal any additional effect in LNCaP and DU145 cells, whereas it enhanced the secretion of NO in PC3 cells. Polyphenols decreased NO secretion. This effect correlates with their antiproliferative action and the inhibition of inducible NO synthase. It is therefore proposed that the antiproliferative effect of polyphenols is mediated through the modulation of NO production. In conclusion, our data show a direct inhibitory effect of low concentrations of antioxidant wine phenols on the proliferation of human prostate cancer cell lines mediated by the production of NO, further suggesting potential beneficial effects of wine and other phenol-containing foods or drinks for the control of prostate cancer cell growth.

Holography and Thermodynamics of 5D Dilaton-gravity

Abstract: The asymptotically-logarithmically-AdS black-hole solutions of 5D dilaton gravity with a monotonic dilaton potential are analyzed in detail. Such theories are holographically very close to pure Yang-Mills theory in four dimensions. The existence and uniqueness of black-hole solutions is shown. It is also shown that a Hawking-Page transition exists at finite temperature if and only if the potential corresponds to a confining theory. The physics of the transition matches in detail with that of deconfinement of the Yang-Mills theory. The high-temperature phase asymptotes to a free gluon gas at high temperature matching the expected behavior from asymptotic freedom. The thermal gluon condensate is calculated and shown to be crucial for the existence of a non-trivial deconfining transition. The condensate of the topological charge is shown to vanish in the deconfined phase.