Institution
University of Crete
Education•Rethymno, Greece•
About: University of Crete is a education organization based out in Rethymno, Greece. It is known for research contribution in the topics: Population & Galaxy. The organization has 8681 authors who have published 21684 publications receiving 709078 citations. The organization is also known as: Panepistimio Kritis.
Topics: Population, Galaxy, Cancer, Context (language use), Laser
Papers published on a yearly basis
Papers
More filters
••
TL;DR: In this paper, the long-term impacts of forest fires on climate, new sophisticated tools have recently become available (observational and modeling) to understand the processes involved and the environmental consequences of fires.
Abstract: Fire has a role in ecosystem services; naturally produced wildfires are important for the sustainability of many terrestrial biomes and fire is one of nature's primary carbon-cycling mechanisms. Under a warming climate, it is likely that fire frequency and severity will increase. There is some evidence that fire activity may already be increasing in Western U.S. forests and recent exceptionally intense fire events, such as the Australian Black Saturday fires in 2009 and Russian fires in 2010, highlight the devastation of fires associated with extreme weather. The impacts of emissions from fires on global atmospheric chemistry, and on the atmospheric burden of greenhouse gases and aerosols are recognized although gaps remain in our scientific understanding of the processes involved and the environmental consequences of fires. While significant uncertainty remains in the long-term impacts of forest fires on climate, new sophisticated tools have recently become available (observational and modeling). These t...
141 citations
••
University of Crete1, University of Thessaly2, Far Eastern Federal University3, University of Granada4, Chonnam National University5, University of Messina6, Gazi University7, Carol Davila University of Medicine and Pharmacy8, University of Medicine and Pharmacy of Craiova9, RMIT University10, University of Turku11, Michigan State University12
TL;DR: If the hypothesis of an increased risk or a new hazard not currently identified from cumulative exposure to multiple chemicals was observed, this will provide further information to public authorities and research communities supporting the need of replacing current single-compound risk assessment by a more robust cumulative risk assessment paradigm.
Abstract: In real life, consumers are exposed to complex mixtures of chemicals via food, water and commercial products consumption Since risk assessment usually focuses on individual compounds, the current regulatory approach doesn't assess the overall risk of chemicals present in a mixture This study will evaluate the cumulative toxicity of mixtures of different classes of pesticides and mixtures of different classes of pesticides together with food additives (FAs) and common consumer product chemicals using realistic doses after long-term exposure Groups of Sprague Dawley (CD-SD) rats (20 males and 20 females) will be treated with mixtures of pesticides or mixtures of pesticides together with FAs and common consumer product chemicals in 00, 025 × acceptable daily intake (ADI)/tolerable daily intake (TDI), ADI/TDI and 5 × ADI/TDI doses for 104 weeks All animals will be examined every day for signs of morbidity and mortality Clinical chemistry hematological parameters, serum hormone levels, biomarkers of oxidative stress, cardiotoxicity, genotoxicity, urinalysis and echocardiographic tests will be assessed periodically at 6 month intervals At 3-month intervals, ophthalmological examination, test for sensory reactivity to different types of stimuli, together with assessment of learning abilities and memory performance of the adult and ageing animals will be conducted After 24 months, animals will be necropsied, and internal organs will be histopathologically examined If the hypothesis of an increased risk or a new hazard not currently identified from cumulative exposure to multiple chemicals was observed, this will provide further information to public authorities and research communities supporting the need of replacing current single-compound risk assessment by a more robust cumulative risk assessment paradigm
140 citations
••
TL;DR: It is proven here that for Vandermonde channel vectors, it is possible to recast the optimization in terms of the autocorrelation sequences of the sought beam vectors, yielding an equivalent convex reformulation in the efficient optimal solution using modern interior point methods.
Abstract: The problem of transmit beamforming to multiple cochannel multicast groups is considered for the important special case when the channel vectors are Vandermonde. This arises when a uniform linear antenna antenna (ULA) array is used at the transmitter under far-field line-of-sight propagation conditions, as provisioned in 802.16e and related wireless backhaul scenarios. Two design approaches are pursued: (i) minimizing the total transmitted power subject to providing at least a prescribed received signal-to-interference-plus-noise-ratio (SINR) to each intended receiver; and (ii) maximizing the minimum received SINR under a total transmit power budget. Whereas these problems have been recently shown to be NP-hard, in general, it is proven here that for Vandermonde channel vectors, it is possible to recast the optimization in terms of the autocorrelation sequences of the sought beam vectors, yielding an equivalent convex reformulation. This affords efficient optimal solution using modern interior point methods. The optimal beam vectors can then be recovered using spectral factorization. Robust extensions for the case of partial channel state information, where the direction of each receiver is known to lie in an interval, are also developed. Interestingly, these also admit convex reformulation. The various optimal designs are illustrated and contrasted in a suite of pertinent numerical experiments.
140 citations
••
Alfred Wegener Institute for Polar and Marine Research1, Paul Scherrer Institute2, Leibniz Association3, Stockholm University4, Norwegian Institute for Air Research5, University of Crete6, University of Birmingham7, King Abdulaziz University8, Spanish National Research Council9, University of Clermont-Ferrand10, Lund University11, University of Grenoble12, University of Helsinki13
TL;DR: In this article, the authors investigated the spatio-temporal variability of the mass absorption cross-section (MAC) of atmospheric black carbon, defined as light absorption coefficient (σap) divided by elemental carbon mass concentration (mEC).
140 citations
••
University of Marburg1, National Institutes of Health2, McMaster University3, University of Manchester4, National and Kapodistrian University of Athens5, University of Crete6, Transylvania University7, Ghent University Hospital8, Charité9, Woolcock Institute of Medical Research10, Humanitas University11, University of Cartagena12, University of South Florida13, University of Porto14, Federal University of Bahia15, King's College London16, Saint Louis University17, Hospital Clínico San Carlos18, Erasmus University Rotterdam19, University of Helsinki20, Odense University Hospital21, Katholieke Universiteit Leuven22, University of Amsterdam23, Chiba University24, Wrocław Medical University25, Ukrainian Medical Stomatological Academy26, Hacettepe University27, Medical University of Łódź28, Boston Children's Hospital29, Vilnius University30, National Research Council31, University of Oslo32, Oslo University Hospital33, University of Beira Interior34, University of Copenhagen35, University of Naples Federico II36, University of Barcelona37, Monash University38, University of Messina39, Ajou University40, Charles University in Prague41, University of Genoa42, Pasteur Institute43, University of Southampton44, Nippon Medical School45, University of Edinburgh46, Medical University of Warsaw47, University College London48, Imperial College London49, Medical University of Graz50, University of Coimbra51, European Union of Medical Specialists52, University of Turku53, University of Bari54, Nova Southeastern University55, Celal Bayar University56
TL;DR: Care pathways for AIT are reviewed using strict criteria and simple recommendations are provided that can be used by all stakeholders including healthcare professionals.
Abstract: Allergen immunotherapy (AIT) is a proven therapeutic option for the treatment of allergic rhinitis and/or asthma. Many guidelines or national practice guidelines have been produced but the evidence-based method varies, many are complex and none propose care pathways. This paper reviews care pathways for AIT using strict criteria and provides simple recommendations that can be used by all stakeholders including healthcare professionals. The decision to prescribe AIT for the patient should be individualized and based on the relevance of the allergens, the persistence of symptoms despite appropriate medications according to guidelines as well as the availability of good-quality and efficacious extracts. Allergen extracts cannot be regarded as generics. Immunotherapy is selected by specialists for stratified patients. There are no currently available validated biomarkers that can predict AIT success. In adolescents and adults, AIT should be reserved for patients with moderate/severe rhinitis or for those with moderate asthma who, despite appropriate pharmacotherapy and adherence, continue to exhibit exacerbations that appear to be related to allergen exposure, except in some specific cases. Immunotherapy may be even more advantageous in patients with multimorbidity. In children, AIT may prevent asthma onset in patients with rhinitis. mHealth tools are promising for the stratification and follow-up of patients.
140 citations
Authors
Showing all 8725 results
Name | H-index | Papers | Citations |
---|---|---|---|
Mercouri G. Kanatzidis | 152 | 1854 | 113022 |
T. J. Pearson | 150 | 895 | 126533 |
Stylianos E. Antonarakis | 138 | 746 | 93605 |
William Wijns | 127 | 752 | 95517 |
Andrea Comastri | 111 | 706 | 49119 |
Costas M. Soukoulis | 108 | 644 | 50208 |
Elias Anaissie | 107 | 372 | 42808 |
Jian Zhang | 107 | 3064 | 69715 |
Emmanouil T. Dermitzakis | 101 | 294 | 82496 |
Andreas Engel | 99 | 448 | 33494 |
Nikos C. Kyrpides | 96 | 711 | 62360 |
David J. Kerr | 95 | 544 | 39408 |
Manolis Kogevinas | 95 | 623 | 28521 |
Thomas Walz | 92 | 255 | 29981 |
Jean-Paul Latgé | 91 | 343 | 29152 |