University of East Anglia

About: University of East Anglia is a education organization based out in Norwich, Norfolk, United Kingdom. It is known for research contribution in the topics: Population & Climate change. The organization has 13250 authors who have published 37504 publications receiving 1669060 citations. The organization is also known as: UEA.

Resonance Energy Transfer

Abstract: 1. Resonance energy transfer in proteins introduction some basic considerations a short history of FRET determinations the components of the Foorster equation quantum yield determining spectral overlap steady state or time--resolved measurements? resonance energy transfer using intrinsic amino acids homotransfer between intrinsic probes heterotransfer the range of distances determined by resonance energy transfer precise location of resonance energy transfer probes properties of probes labeling specific residues in proteins resonance energy transfer experiments using lanthanide ions measurements in radially symmetrical systems comparison with crystallographic distances using resonance energy transfer to constrain molecular models resonance energy transfer with single fluorophores: new wave experiments intramolecular energy transfer in proteins bound to membranes green fluorescent protein resonance energy transfer and biosensors: a new and promising technique shortcomings the future of FRET summary dedication acknowledgements references. 2. Unified theory and radiative and raditionless energy transfer introduction background the basis of the unified theory spectral features refraction and dissipation dynamics of energy transfer between a pair of molecules in a dielectric medium conclusion appendix A: Heitler--MA method for analysis of the transition operator Appendix B: modified approach to the transition operator references. 3. Dynamics of radiative transport introduction overview of atomic and molecular radiative transport the Holstein--Biberman equation multiple scattering representation stochastic approach combined radiative and nonradiative transport conclusion appendix A: probablitity of emission of a photon between t + dt for an nth generation molecule appendix B: depolarization factor for radiative transferaccording to classical electrodynamics references. 4. Orientational aspects in pair energy transfer introduction Kappa--squared and probability, Kappa--squared and anisotropy notes on the effects of order and motion acknowledgements references. 5. Polarization in molecular complexes with incoherent energy transfer introduction interaction of light with single molecules or chromophores bichromophore molecular complexes trichromophore complexes multichromophore complexes with C3 symmetry conclusion appendix A appendix B appendix C appendix D references. 6. Theory of coupling in multichromophoric systems introduction reactant and product states: LMO model the origin of coupling matrix elements paradigmatic results coulombic coupling superexchange interpretation of steady state spectra calculation of couplings acknowledgements references. 7. Exciton annihilation in molecular aggregates introduction theory applications discussion acknowledgements references. 8. Energy transfer and localization: applications to photosynthetic systems introduction optical properties of dimers and aggregates energy and localization in antenna complexes and reaction centers acknowledgements references. 9.Excitation energy transfer in photosynthesis introduction the structure of light--harvesting complexes the mechanism of energy transfer and trapping in photosynthesis dynamics of excitation energy transfer conclusions acknowledgements references. 10. The Fenna--Matthews--Olson protein: a strongly coupled photosynthetic antenna introduction steady state spectroscopy FMO exciton simulations FMO primary processes epilog and future prospects acknowledgements references. 11. Use of a Monte carlo method in the problem of energy migration in molecular complexes introduction an illustration of Monte Carlo calculations in the problem of fluorescence decay energy transfer in CME: major algorithm applications of monte Carlo simulations conclusion acknowledgements references. Index

Implications for neurobiological research of cognitive models of psychosis: a theoretical paper.

Abstract: BackgroundCognitive models of the positive symptoms of psychosis specify the cognitive, social and emotional processes hypothesized to contribute to their occurrence and persistence, and propose that vulnerable individuals make characteristic appraisals that result in specific positive symptoms.MethodWe describe cognitive models of positive psychotic symptoms and use this as the basis of discussing recent relevant empirical investigations and reviews that integrate cognitive approaches into neurobiological frameworks.ResultsEvidence increasingly supports a number of the hypotheses proposed by cognitive models. These are that: psychosis is on a continuum; specific cognitive processes are risk factors for the transition from subclinical experiences to clinical disorder; social adversity and trauma are associated with psychosis and with negative emotional processes; and these emotional processes contribute to the occurrence and persistence of psychotic symptoms. There is also evidence that reasoning biases contribute to the occurrence of delusions.ConclusionsThe benefits of incorporating cognitive processes into neurobiological research include more sophisticated, bidirectional and interactive causal models, the amplification of phenotypes in neurobiological investigations by including emotional processes, and the adoption of more specific clinical phenotypes. For example, there is potential value in studying gene×environment×cognition/emotion interactions. Cognitive models and their derived phenotypes constitute the missing link in the chain between genetic or acquired biological vulnerability, the social environment and the expression of individual positive symptoms.

The next release problem

Abstract: Companies developing and maintaining complex software systems need to determine the features that should be added to their system as part of the next release. They will wish to select these features to ensure the demands of their client base are satisfied as much as possible while at the same time ensuring that they themselves have the resources to undertake the necessary development. This situation is modelled in this paper and the problem of selecting an optimal next release is shown to be NP-hard. The use of various modern heuristics to find a high quality but possibly suboptimal solution is described. Comparative studies of these heuristics are given for various test cases.

Conservation Value of Remnant Riparian Forest Corridors of Varying Quality for Amazonian Birds and Mammals

Abstract: Forest corridors are often considered the main instrument with which to offset the effects of habitat loss and fragmentation. Brazilian forestry legislation requires that all riparian zones on private landholdings be maintained as permanent reserves and sets fixed minimum widths of riparian forest buffers to be retained alongside rivers and perennial streams. We investigated the effects of corridor width and degradation status of 37 riparian forest sites (including 24 corridors connected to large source-forest patches, 8 unconnected forest corridors, and 5 control riparian zones embedded within continuous forest patches) on bird and mammal species richness in a hyper-fragmented forest landscape surrounding Alta Floresta, Mato Grosso, Brazil. We used point-count and track-sampling methodology, coupled with an intensive forest-quality assessment that combined satellite imagery and ground truthed data. Vertebrate use of corridors was highly species-specific, but broad trends emerged depending on species life histories and their sensitivity to disturbance. Narrow and/or highly disturbed riparian corridors retained only a depauperate vertebrate assemblage that was typical of deforested habitats, whereas wide, well-preserved corridors retained a nearly complete species assemblage. Restriction of livestock movement along riparian buffers and their exclusion from key areas alongside deforested streams would permit corridor regeneration and facilitate restoration of connectivity.