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Institution

University of Exeter

EducationExeter, United Kingdom
About: University of Exeter is a education organization based out in Exeter, United Kingdom. It is known for research contribution in the topics: Population & Context (language use). The organization has 15820 authors who have published 50650 publications receiving 1793046 citations. The organization is also known as: Exeter University & University of the South West of England.


Papers
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Journal ArticleDOI
04 Sep 2014-Nature
TL;DR: It is found that the substantial carbon stores in Arctic and boreal soils could be more vulnerable to climate warming than currently predicted.
Abstract: Soils store about four times as much carbon as plant biomass, and soil microbial respiration releases about 60 petagrams of carbon per year to the atmosphere as carbon dioxide. Short-term experiments have shown that soil microbial respiration increases exponentially with temperature. This information has been incorporated into soil carbon and Earth-system models, which suggest that warming-induced increases in carbon dioxide release from soils represent an important positive feedback loop that could influence twenty-first-century climate change. The magnitude of this feedback remains uncertain, however, not least because the response of soil microbial communities to changing temperatures has the potential to either decrease or increase warming-induced carbon losses substantially. Here we collect soils from different ecosystems along a climate gradient from the Arctic to the Amazon and investigate how microbial community-level responses control the temperature sensitivity of soil respiration. We find that the microbial community-level response more often enhances than reduces the mid- to long-term (90 days) temperature sensitivity of respiration. Furthermore, the strongest enhancing responses were observed in soils with high carbon-to-nitrogen ratios and in soils from cold climatic regions. After 90 days, microbial community responses increased the temperature sensitivity of respiration in high-latitude soils by a factor of 1.4 compared to the instantaneous temperature response. This suggests that the substantial carbon stores in Arctic and boreal soils could be more vulnerable to climate warming than currently predicted.

490 citations

Journal ArticleDOI
TL;DR: Differences between transcriptomic age and chronological age are associated with biological features linked to ageing, such as blood pressure, cholesterol levels, fasting glucose, and body mass index and the transcriptomic prediction model adds biological relevance and complements existing epigenetic prediction models.
Abstract: Disease incidences increase with age, but the molecular characteristics of ageing that lead to increased disease susceptibility remain inadequately understood. Here we perform a whole-blood gene expression meta-analysis in 14,983 individuals of European ancestry (including replication) and identify 1,497 genes that are differentially expressed with chronological age. The age-associated genes do not harbor more age-associated CpG-methylation sites than other genes, but are instead enriched for the presence of potentially functional CpG-methylation sites in enhancer and insulator regions that associate with both chronological age and gene expression levels. We further used the gene expression profiles to calculate the 'transcriptomic age' of an individual, and show that differences between transcriptomic age and chronological age are associated with biological features linked to ageing, such as blood pressure, cholesterol levels, fasting glucose, and body mass index. The transcriptomic prediction model adds biological relevance and complements existing epigenetic prediction models, and can be used by others to calculate transcriptomic age in external cohorts.

490 citations

Journal ArticleDOI
TL;DR: The authors provides an overview of previous work that has explored issues of social, organizational and corporate identity, and calls for greater cross-fertilization of the three identity literatures and discusses requirements for the integration of micro- and macro-level analyses.
Abstract: This paper provides an overview of previous work that has explored issues of social, organizational and corporate identity. Differences in the form and focus of research into these three topics are noted. Social identity work generally examines issues of cognitive process and structure; organizational identity research tends to address the patterning of shared meanings; studies of corporate identity tend to focus on products that communicate a specific image. Nonetheless, across these areas there is general consensus that collective identities are (a) made viable by their positivity and distinctiveness, (b) fluid, (c) a basis for shared perceptions and action, (d) strategically created and managed, (e) qualitatively different from individual identities and (f) the basis for material outcomes and products. This paper calls for greater cross-fertilization of the three identity literatures and discusses requirements for the integration of micro- and macro-level analyses.

486 citations

Journal ArticleDOI
TL;DR: It is concluded that the ingestible telemetric temperature sensor represents a valid index of Tc and shows excellent utility for ambulatory field-based applications.
Abstract: An ingestible telemetric temperature sensor for measuring body core temperature (Tc) was first described 45 years ago, although the method has only recently gained widespread use for exercise applications. This review aims to (1) use Bland and Altman's limits of agreement (LoA) method as a basis for quantitatively reviewing the agreement between intestinal sensor temperature (Tintestinal), oesophageal temperature (Toesophageal) and rectal temperature (Trectal) across numerous previously published validation studies; (2) review factors that may affect agreement; and (3) review the application of this technology in field-based exercise studies. The agreement between Tintestinal and Toesophageal is suggested to meet our delimitation for an acceptable level of agreement (ie, systematic bias 0.1 degrees C, although the 95% LoA is acceptable. Tintestinal responds less rapidly than Toesophageal at the start or cessation of exercise or to a change in exercise intensity, but more rapidly than Trectal. When using this technology, care should be taken to ensure adequate control over sensor calibration and data correction, timing of ingestion and electromagnetic interference. The ingestible sensor has been applied successfully in numerous sport and occupational applications such as the continuous measurement of Tc in deep sea saturation divers, distance runners and soldiers undertaking sustained military training exercises. It is concluded that the ingestible telemetric temperature sensor represents a valid index of Tc and shows excellent utility for ambulatory field-based applications.

484 citations

Posted Content
TL;DR: The authors provide insights into the particularities of interviewing elites for those new to researching this group, focusing on gaining trust and gauging the tone of the interview, how to present oneself during the interview and the appropriate length of an interview.
Abstract: This paper addresses some strategies for conducting elite interviews. It draws upon material from a significant number of interviews that the author has conducted with this group in a variety of economic sectors and countries, as well as from the social sciences literature on elites. The aim of the paper is to provide insights into the particularities of interviewing elites for those new to researching this group. In particular, it focuses on gaining trust and gauging the tone of the interview, how to present oneself during the interview, asking open and closed questions, the appropriate length of an interview, whether to record the conversation, coping with difficult scenarios, asking awkward questions, managing respondents who do not answer the question, keeping respondents interested in the interview and finally gaining feedback from respondents.

483 citations


Authors

Showing all 16338 results

NameH-indexPapersCitations
Frank B. Hu2501675253464
John C. Morris1831441168413
David W. Johnson1602714140778
Kevin J. Gaston15075085635
Andrew T. Hattersley146768106949
Timothy M. Frayling133500100344
Joel N. Hirschhorn133431101061
Jonathan D. G. Jones12941780908
Graeme I. Bell12753161011
Mark D. Griffiths124123861335
Tao Zhang123277283866
Brinick Simmons12269169350
Edzard Ernst120132655266
Michael Stumvoll11965569891
Peter McGuffin11762462968
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023295
2022782
20214,412
20204,192
20193,721
20183,385