University of Exeter

About: University of Exeter is a education organization based out in Exeter, United Kingdom. It is known for research contribution in the topics: Population & Context (language use). The organization has 15820 authors who have published 50650 publications receiving 1793046 citations. The organization is also known as: Exeter University & University of the South West of England.

Vitamin D and Risk of Cognitive Decline in Elderly Persons

Abstract: Background: To our knowledge, no prospective study has examined the association between vitamin D and cognitive decline or dementia. Methods: We determined whether low levels of serum 25-hydroxyvitamin D (25[OH]D) were associated with an increased risk of substantial cognitive decline in the InCHIANTI population–based study conducted in Italy between 1998 and 2006 with follow-up assessments every 3 years. A total of 858 adults 65 years or older completed interviews, cognitive assessments, and medical examinations and provided blood samples. Cognitive decline was assessed using the Mini-Mental State Examination (MMSE), and substantial decline was defined as 3 or more points. The Trail-Making Tests A and B were also used, and substantial decline was defined as the worst 10% of the distribution of decline or as discontinued testing. Results: The multivariate adjusted relative risk (95% confidence interval [CI]) of substantial cognitive decline on the MMSE in participants who were severely serum 25 (OH)D deficient (levels25 nmol/L) in comparison with those with sufficient levels of 25(OH)D (75 nmol/L) was 1.60 (95% CI, 1.19-2.00). Multivariate adjusted random-effects models demonstrated that the scores of participants who were severely 25(OH)D deficient declined by an additional 0.3 MMSE points per year more than those with sufficient levels of 25(OH)D. The relative risk for substantial decline on Trail-Making Test B was 1.31 (95% CI, 1.03-1.51) among those who were severely 25(OH)D deficient compared with those with sufficient levels of 25(OH)D. No significant association was observed for Trail-Making Test A. Conclusion: Low levels of vitamin D were associated with substantial cognitive decline in the elderly population studied over a 6-year period, which raises important new possibilities for treatment and prevention. Arch Intern Med. 2010;170(13):1135-1141

The Individual Within the Group: Balancing the Need to Belong With the Need to Be Different

Abstract: Many theorists have wrestled with the notion of how people balance their need to be included in social groups with their need to be different and distinctive. This question is particularly salient to researchers from the social identity perspective, who have traditionally viewed individual differentiation within groups as being inimical to group identification. In this article we present a number of strategies that people can use to balance their need to belong and their need to be different, without violating social identity principles. First, drawing from optimal distinctiveness theory, we discuss 4 ways in which the need for belonging and the need to be different can be resolved by maximizing group distinctiveness. We then discuss 4 ways in which it is possible to achieve individual differentiation within a group at the same time demonstrating group identification. These strategies are discussed and integrated with reference to recent empirical research and to the social identity perspective.

Hubble Space Telescope transmission spectroscopy of the exoplanet HD 189733b: high‐altitude atmospheric haze in the optical and near‐ultraviolet with STIS

Abstract: We present Hubble Space Telescope (HST) optical and near-ultraviolet transmission spectra of the transiting hot Jupiter HD 189733b, taken with the repaired Space Telescope Imaging Spectrograph (STIS) instrument. The resulting spectra cover the range 2900–5700 A and reach per exposure signal-to-noise ratio levels greater than 11 000 within a 500-A bandwidth. We used time series spectra obtained during two transit events to determine the wavelength dependence of the planetary radius and measure the exoplanet’s atmospheric transmission spectrum for the first time over this wavelength range. Our measurements, in conjunction with existing HST spectra, now provide a broad-band transmission spectrum covering the full optical regime. The STIS data also show unambiguous evidence of a large occulted stellar spot during one of our transit events, which we use to place constraints on the characteristics of the K dwarf’s stellar spots, estimating spot temperatures around T eff ∼ 4250 K. With contemporaneous ground-based photometric monitoring of the stellar variability, we also measure the correlation between the stellar activity level and transit-measured planet-to-star radius contrast, which is in good agreement with predictions. We find a planetary transmission spectrum in good agreement with that of Rayleigh scattering from a high-altitude atmospheric haze as previously found from HST Advanced Camera for Surveys. The high-altitude haze is now found to cover the entire optical regime and is well characterized by Rayleigh scattering. These findings suggest that haze may be a globally dominant atmospheric feature of the planet which would result in a high optical albedo at shorter optical wavelengths.