University of Memphis

About: University of Memphis is a education organization based out in Memphis, Tennessee, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 7710 authors who have published 20082 publications receiving 611618 citations. The organization is also known as: U of M.

Animal models for medications development targeting alcohol abuse using selectively bred rat lines: neurobiological and pharmacological validity.

Abstract: The purpose of this review paper is to present evidence that rat animal models of alcoholism provide an ideal platform for developing and screening medications that target alcohol abuse and dependence. The focus is on the 5 oldest international rat lines that have been selectively bred for a high alcohol-consumption phenotype. The behavioral and neurochemical phenotypes of these rat lines are reviewed and placed in the context of the clinical literature. The paper presents behavioral models for assessing the efficacy of pharmaceuticals for the treatment of alcohol abuse and dependence in rodents, with particular emphasis on rats. Drugs that have been tested for their effectiveness in reducing alcohol/ethanol consumption and/or self-administration by these rat lines and their putative site of action are summarized. The paper also presents some current and future directions for developing pharmacological treatments targeting alcohol abuse and dependence.

Corporate social responsibility: Implications for performance excellence

Abstract: Corporate social responsibility has been an element of the Malcolm Baldrige Criteria for Performance Excellence since its inception in 1988. The Baldrige Criteria provide a framework for the design and improvement of high-performing organisations; as such, it implies that corporate social responsibility is an important factor for achieving performance excellence. Corporate social responsibility has garnered much attention from researchers over the past several decades, with most questions focusing on whether a company that is socially responsible is more likely to be financially successful. This paper examines the underlying corporate social responsibility value proposition within the Baldrige Criteria in comparison with current academic thought. We frame corporate social responsibility in terms of the underlying theories of firm management, review current academic thought and research, and draw conclusions on the relevance of corporate social responsibility for performance excellence in the Baldrige crit...