University of North Carolina at Charlotte

About: University of North Carolina at Charlotte is a education organization based out in Charlotte, North Carolina, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 8772 authors who have published 22239 publications receiving 562529 citations. The organization is also known as: UNC Charlotte & UNCC.

Hydrologic effects of the expansion of rubber (Hevea brasiliensis) in a tropical catchment

Abstract: This study investigates basin-scale hydrologic implications of the replacement of forest-dominated land cover by rubber plantations in Montane Mainland Southeast Asia. The paper presents a new method for estimating the water demand of rubber and consequently water losses to the atmosphere through rubber evapotranspiration (ET). In this paper we argue that rubber ET is energy-limited during the wet season, but during the dry season water consumption is mostly governed by environmental variables that directly affect rubber phenology, namely, vapour pressure deficit, temperature and photoperiodicity. The proposed ET model is introduced into a hillslope-based hydrologic model to predict the basin-scale hydrologic consequences of rubber replacing native vegetation. Simulations suggest greater annual catchment water losses through ET from rubber dominated landscapes compared to traditional vegetation cover. This additional water use reduces discharge from the basin, or its storage. Copyright © 2010 John Wiley & Sons, Ltd.

Nonprofits, Funders, and Evaluation: Accountability in Action

Abstract: This article examines the extent to which different types of funders are asking nonprofit organizations for evaluation and performance measurement data, and describes the many ways in which nonprof...

The Interleukin-10 Family of Cytokines and Their Role in the CNS.

Abstract: Resident cells of the central nervous system (CNS) play an important role in detecting insults and initiating protective or sometimes detrimental host immunity. At peripheral sites, immune responses follow a biphasic course with the rapid, but transient, production of inflammatory mediators giving way to the delayed release of factors that promote resolution and repair. Within the CNS, it is well known that glial cells contribute to the onset and progression of neuroinflammation, but it is only now becoming apparent that microglia and astrocytes also play an important role in producing and responding to immunosuppressive factors that serve to limit the detrimental effects of such responses. Interleukin-10 (IL-10) is generally considered to be the quintessential immunosuppressive cytokine, and its ability to resolve inflammation and promote wound repair at peripheral sites is well documented. In the present review article, we discuss the evidence for the production of IL-10 by glia, and describe the ability of CNS cells, including microglia and astrocytes, to respond to this suppressive factor. Furthermore, we review the literature for the expression of other members of the IL-10 cytokine family, IL-19, IL-20, IL-22 and IL-24, within the brain, and discuss the evidence of a role for these poorly understood cytokines in the regulation of infectious and sterile neuroinflammation. In concert, the available data indicate that glia can produce IL-10 and the related cytokines IL-19 and IL-24 in a delayed manner, and these cytokines can limit glial inflammatory responses and/or provide protection against CNS insult. However, the roles of other IL-10 family members within the CNS remain unclear, with IL-20 appearing to act as a pro-inflammatory factor, while IL-22 may play a protective role in some instances and a detrimental role in others, perhaps reflecting the pleiotropic nature of this cytokine family. What is clear is that our current understanding of the role of IL-10 and related cytokines within the CNS is limited at best, and further research is required to define the actions of this understudied family in inflammatory brain disorders.

Development, reliability, and validity of the Measure of Sexual Identity Exploration and Commitment (MOSIEC).

Abstract: Four studies were conducted on the development and validation of the Measure of Sexual Identity Exploration and Commitment (MoSIEC). Exploratory factor analysis of an initial item pool yielded a 22-item measure with 4 distinct factors assessing commitment, exploration, sexual orientation identity uncertainty, and synthesis/integration. Exploratory factor analysis findings support the argument that sexual identity is a broad, multidimensional construct and that the MoSIEC assesses the construct of sexual identity in a manner consistent with J. E. Marcia's (1966) model of identity development. Confirmatory factor analyses demonstrated the stability of the MoSIEC factor structure, providing evidence of construct validity. Test-retest stability, internal consistency, and validity coefficients supported the use and continued development of the MoSIEC. Significant differences in levels of exploration and sexual orientation identity uncertainty were found among different sexual orientation identity groups, establishing the criterion-related validity of the MoSIEC. Implications for further development and use of the MoSIEC are discussed.