Journal ArticleDOI
A review of chitin and chitosan applications
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TLDR
Chitin is the most abundant natural amino polysaccharide and is estimated to be produced annually almost as much as cellulose, and recent progress in chitin chemistry is quite noteworthy as mentioned in this paper.Abstract:
Chitin is the most abundant natural amino polysaccharide and is estimated to be produced annually almost as much as cellulose. It has become of great interest not only as an underutilized resource, but also as a new functional material of high potential in various fields, and recent progress in chitin chemistry is quite noteworthy. The purpose of this review is to take a closer look at chitin and chitosan applications. Based on current research and existing products, some new and futuristic approaches in this fascinating area are thoroughly discussed.read more
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Encapsulation of glucose oxidase (GOD) in polyelectrolyte complexes of chitosan-carrageenan
TL;DR: In this article, the potential ability of carrageenan (κ-, ι-, λ-) and chitosan to form a controlled-release system for glucose oxidase (GOD) was investigated.
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Chitosan and its use in design of insulin delivery system.
TL;DR: The overview of various recent patented strategies on non-injection insulin delivery denotes the significance of chitosan for its mucoadhesive and able to protect the insulin from enzymatic degradation, prolong the retention time of insulin, as well as open the inter-epithelial tight junction to facilitate systemic insulin transport.
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Chitosan as a reusable solid base catalyst for Knoevenagel condensation reaction
TL;DR: Chitosan is reported as a heterogeneous solid base catalyst for Knoevenagel condensation reaction of carbonyl compounds with malononitrile under mild reaction conditions and it is observed that the catalyst can be reused for four times with no significant drop in its activity.
Journal ArticleDOI
Ionic liquids for the preparation of biopolymer materials for drug/gene delivery: a review
TL;DR: An overview of the recent progress in using ILs for the engineering of next-generation drug/gene delivery carrier materials is provided, and the tunable properties of ILs as affected by their structures are highlighted.
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Using Zebrafish for Investigating the Molecular Mechanisms of Drug-Induced Cardiotoxicity
Zain Zaki Zakaria,Fatiha M. Benslimane,Gheyath K. Nasrallah,Gheyath K. Nasrallah,Samar Shurbaji,Nadin Younes,Fatima Mraiche,Sahar I. Da'as,Huseyin C. Yalcin +8 more
TL;DR: This review provided a summary for recent studies that have used zebrafish to investigate the molecular mechanisms of drug-induced cardiotoxicity and described several microscopic imaging and analysis protocols that are being used for the estimation of a variety of cardiac hemodynamic parameters.
References
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Book
Encyclopedia of polymer science and engineering
TL;DR: In this paper, the authors describe a chain transfer characterisation of polymers charge-transfer complexes, charge transfer complexes and charge transfer complexes of charge transfer and charge-Transfer complexes.
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A simple equation for description of solute release I. Fickian and non-fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs
TL;DR: In this paper, a simple exponential relation Mt/M∞ = ktn is introduced to describe the general solute release behavior of controlled release polymeric devices, where Mt is the fractional release, t is the release time, k is a constant, and n is the diffusional exponent characteristic of the release mechanism.
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Biodegradable long-circulating polymeric nanospheres
Ruxandra Gref,Yoshiharu Minamitake,Maria Teresa Peracchia,Vladimir S. Trubetskoy,Vladimir P. Torchilin,Robert Langer +5 more
TL;DR: Monodisperse biodegradable nanospheres were developed from amphiphilic copolymers composed of two biocompatible blocks and exhibited dramatically increased blood circulation times and reduced liver accumulation in mice.
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Polymeric Systems for Controlled Drug Release
TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
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Novel hydrophilic chitosan-polyethylene oxide nanoparticles as protein carriers
TL;DR: In this paper, a new approach for the preparation of nanoparticles made solely of hydrophilic polymers is presented, based on an ionic gelation process, is extremely mild and involves the mixture of two aqueous phases at room temperature.