Journal ArticleDOI
A review of chitin and chitosan applications
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Chitin is the most abundant natural amino polysaccharide and is estimated to be produced annually almost as much as cellulose, and recent progress in chitin chemistry is quite noteworthy as mentioned in this paper.Abstract:
Chitin is the most abundant natural amino polysaccharide and is estimated to be produced annually almost as much as cellulose. It has become of great interest not only as an underutilized resource, but also as a new functional material of high potential in various fields, and recent progress in chitin chemistry is quite noteworthy. The purpose of this review is to take a closer look at chitin and chitosan applications. Based on current research and existing products, some new and futuristic approaches in this fascinating area are thoroughly discussed.read more
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Injectable chitosan hydrogels for localised cancer therapy.
TL;DR: This review focuses on the current use of injectable in situ chitosan hydrogels in cancer treatment and their cytotoxic properties, loading and in vitro release of drugs, their effect on cell growth in vitro and inhibition of tumor growth in vivo using mouse models.
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Chitin-based tubes for tissue engineering in the nervous system.
TL;DR: The methods for easy processing and modification of chitin and chitosan described herein, allow the mechanical properties and cyto-compatibility to be controlled and provide a means for a broader investigation into their use in biomedical applications.
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Application, mode of action, and in vivo activity of chitosan and its micro- and nanoparticles as antimicrobial agents: A review.
TL;DR: This review will focus on recent studies of in vivo antimicrobial activity of chitosan and its micro- and nanoparticles to enhance food safety and animal diseases treatment.
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Preparation and antibacterial activity of a water-soluble chitosan derivative
TL;DR: In this paper, a copolymer called hydroxypropyl chitosan (HPCTS) was used to obtain multiple-derivated chitosa, maleic acid sodium (MAS) was grafted onto HPCTS at 70°C for 2h in an aqueous solution using ammonium persulfate as an initiator.
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Chitosan/halloysite nanotubes bionanocomposites: structure, mechanical properties and biocompatibility.
TL;DR: In vitro fibroblasts response demonstrates that both chitosan and chitOSan/HNTs nanocomposite films are cytocompatibility even when the loading of HNTs is 10%.
References
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Book
Encyclopedia of polymer science and engineering
TL;DR: In this paper, the authors describe a chain transfer characterisation of polymers charge-transfer complexes, charge transfer complexes and charge transfer complexes of charge transfer and charge-Transfer complexes.
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A simple equation for description of solute release I. Fickian and non-fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs
TL;DR: In this paper, a simple exponential relation Mt/M∞ = ktn is introduced to describe the general solute release behavior of controlled release polymeric devices, where Mt is the fractional release, t is the release time, k is a constant, and n is the diffusional exponent characteristic of the release mechanism.
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Biodegradable long-circulating polymeric nanospheres
Ruxandra Gref,Yoshiharu Minamitake,Maria Teresa Peracchia,Vladimir S. Trubetskoy,Vladimir P. Torchilin,Robert Langer +5 more
TL;DR: Monodisperse biodegradable nanospheres were developed from amphiphilic copolymers composed of two biocompatible blocks and exhibited dramatically increased blood circulation times and reduced liver accumulation in mice.
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Polymeric Systems for Controlled Drug Release
TL;DR: Kevin Shakesheff investigates new methods of engineering polymer surfaces and the application of these engineered materials in drug delivery and tissue engineering.
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Novel hydrophilic chitosan-polyethylene oxide nanoparticles as protein carriers
TL;DR: In this paper, a new approach for the preparation of nanoparticles made solely of hydrophilic polymers is presented, based on an ionic gelation process, is extremely mild and involves the mixture of two aqueous phases at room temperature.