Journal ArticleDOI
Disorders of iron metabolism.
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TLDR
Iron has the capacity to accept and donate electrons readily, interconverting between ferric (Fe2+) and ferrous (Fe3+) forms, which makes it a useful component of cytochromes, oxygen-binding molecules, and many enzymes.Abstract:
Iron has the capacity to accept and donate electrons readily, interconverting between ferric (Fe2+) and ferrous (Fe3+) forms. This capability makes it a useful component of cytochromes, oxygen-bind...read more
Citations
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Alterações moleculares associadas à hemocromatose hereditária
Paulo Caleb Junior Lima Santos,Rodolfo D. Cançado,Cristiane T. Terada,Elvira Maria Guerra-Shinohara +3 more
TL;DR: It is very important to identify the genetic characteristics of this population, as mutations of the HJV, HAMP, TFR2 and SLC40A1 genes may be associated with the pathophysiology of the disease, and there may be interactions between mutations.
Journal ArticleDOI
Radiological evaluations of low cost wollastonite nano-ceramics graft doped with iron oxide in the treatment of induced defects in canine mandible.
Mostafa Mabrouk,Said K. Taha,Mohamed A. Abdel Hamid,Sayed H. Kenawy,Elham A. Hassan,Gehan T. El-Bassyouni +5 more
TL;DR: Clinically, the reconstruction of bone defects was uneventful without any adverse toxic effect, and fabricated nano-ceramics are recommended to be utilized as low cost bone graft alternatives.
A potential relation between telogen effluvium and iron deficiency in adult females
TL;DR: Serum ferritin levels may be of value in the evaluation of adult menstruating women with chronic diffuse hair loss because of a significant association between low serum ferritIn levels and chronic telogen effluvium.
Journal ArticleDOI
Bioavailability of Iron from Cereal Products Enriched with Dried Shittake Mushrooms (Lentinula edodes) as Determined by Iron Regeneration Efficacy Method in Female Rats
TL;DR: Assessment of the bioavailability of iron from cereal products with the addition of dried shiitake mushrooms using the iron regeneration efficacy method in Fe-deficient female rats found that it is comparable to that of Fe(II) gluconate.
Journal ArticleDOI
A Highly Selective and Sensitive Turn‐On Fluorescent Chemosensor Based on Rhodamine 6G for Iron(III)
TL;DR: The robust nature of the sensor was shown by the detection of Fe3+ even after repeated rounds of quenching, indicating the regeneration of the chemosensor RAE.
References
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Journal ArticleDOI
A novel MHC class I–like gene is mutated in patients with hereditary haemochromatosis
John N. Feder,Andreas Gnirke,Winston Thomas,Zenta Tsuchihashi,David A. Ruddy,A. Basava,F. Dormishian,R. Domingo,Michael C. Ellis,A. Fullan,L.M. Hinton,Norman Jones,B.E. Kimmel,Gregory S. Kronmal,Peter M. San Francisco Lauer,V.K. Lee,Deborah B. Loeb,Felipa A. Mapa,Erin E. McClelland,Nicole C. Meyer,Gabe Mintier,N. Moeller,T. E. Moore,E. Morikang,Cynthia E. Prass,Leah Quintana,Steven M. Starnes,Randall C. Schatzman,K.J. Brunke,Dennis Drayna,Neil Risch,Bruce R. Bacon,Roger K. Wolff +32 more
TL;DR: Using linkage-disequilibrium and full haplotype analysis, this paper identified a 250-kilobase region more than 3 megabases telomeric of the major histocompatibility complex (MHC) that is identical-by-descent in 85% of patient chromosomes.
Journal Article
A novel MHC class-I-like gene is mutated in patients with hereditary haemochromatosis
TL;DR: Using linkage–disequilibrium and full haplotype analysis, a region more than 3 megabases telomeric of the major histocompatibility complex (MHC) that is identical–by–descent in 85% of patient chromosomes is identified, containing a gene related to the MHC class I family, termed HLA–H, containing two missense alterations.
Journal ArticleDOI
Cloning and characterization of a mammalian proton-coupled metal-ion transporter
Hiromi Gunshin,Bryan Mackenzie,Urs V. Berger,Yoshimi Gunshin,Michael F. Romero,Walter F. Boron,Stephan Nussberger,John L. Gollan,Matthias A. Hediger +8 more
TL;DR: A new metal-ion transporter in the rat, DCT1, which has an unusually broad substrate range that includes Fe2+, Zn2+, Mn2+, Co2+, Cd2+, Cu2+, Ni2+ and Pb2+.
Journal ArticleDOI
Prevalence of Iron Deficiency in the United States
TL;DR: Iron deficiency and iron deficiency anemia are still relatively common in toddlers, adolescent girls, and women of childbearing age and were more likely in those who are minority, low income, and multiparous.
Journal ArticleDOI
Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene.
Joseph V. Gray,Keith J. Johnson +1 more
TL;DR: A positional cloning strategy is undertaken to identify the causative mutation in mice with microcytic anaemia, and it is suggested that the phenotype is a consequence of a missense mutation in Nramp2 (ref. 5), a previously identified gene of unknown function.
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