GENEVESTIGATOR. Arabidopsis Microarray Database and Analysis Toolbox
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TLDR
Genevestigator as mentioned in this paper is a web-browser interface for gene expression analysis using Affymetrix GeneChip data, which allows users to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs.Abstract:
High-throughput gene expression analysis has become a frequent and powerful research tool in biology. At present, however, few software applications have been developed for biologists to query large microarray gene expression databases using a Web-browser interface. We present GENEVESTIGATOR, a database and Web-browser data mining interface for Affymetrix GeneChip data. Users can query the database to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs. Reversely, mining tools allow users to identify genes specifically expressed during selected stresses, growth stages, or in particular organs. Using GENEVESTIGATOR, the gene expression profiles of more than 22,000 Arabidopsis genes can be obtained, including those of 10,600 currently uncharacterized genes. The objective of this software application is to direct gene functional discovery and design of new experiments by providing plant biologists with contextual information on the expression of genes. The database and analysis toolbox is available as a community resource at https://www.genevestigator.ethz.ch.read more
Citations
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The Arabidopsis mitogen-activated protein kinase kinase MKK3 is upstream of group C mitogen-activated protein kinases and participates in pathogen signaling.
Róbert Dóczi,Günter Brader,Aladár Pettkó-Szandtner,Iva Rajh,Armin Djamei,Andrea Pitzschke,Markus Teige,Heribert Hirt +7 more
TL;DR: The results reveal that the MKK3 pathway plays a role in pathogen defense and further underscore the importance and complexity of MAPK signaling in plant stress responses.
Journal ArticleDOI
The reactive oxygen species network pathways:an essential prerequisite for perception of pathogen attack and the acquired disease resistance in plants.
TL;DR: It is shown here that ROS are ubiquitous molecules of redox-pathways that play a crucial role in plant defence mechanism and the emerging findings of ROS network pathways to modulate multiple stress resistance in plants are described.
Journal ArticleDOI
Arabidopsis Synaptotagmin 1 Is Required for the Maintenance of Plasma Membrane Integrity and Cell Viability
Arnaldo L. Schapire,Boris Voigt,Boris Voigt,Ján Jásik,Abel Rosado,Rosa Lopez-Cobollo,Diedrik Menzel,Julio Salinas,Stefano Mancuso,Victoriano Valpuesta,František Baluška,Miguel A. Botella +11 more
TL;DR: It is shown that loss of function of the homologous Arabidopsis thaliana Synaptotagmin 1 protein (SYT1) reduces the viability of cells as a consequence of a decrease in the integrity of the plasma membrane.
Journal ArticleDOI
The Arabidopsis vitamin E pathway gene5-1 Mutant Reveals a Critical Role for Phytol Kinase in Seed Tocopherol Biosynthesis
Henry E. Valentin,Kim Lincoln,Farhad Moshiri,Pamela K. Jensen,Qungang Qi,Tyamagondlu V. Venkatesh,Balasulojini Karunanandaa,Susan R. Baszis,Susan R. Norris,Beth Savidge,Kenneth J. Gruys +10 more
TL;DR: The phenotype of the vte5-1 mutant is consistent with the hypothesis that chlorophyll degradation-derived phytol serves as an important intermediate in seed tocopherol synthesis and forces reevaluation of the role of geranylgeranyl diphosphate reductase in tocopHerol biosynthesis.
Journal ArticleDOI
BIGPETALp, a bHLH transcription factor is involved in the control of Arabidopsis petal size
Judit Szécsi,Caroline Joly,Karim Bordji,Emilie Varaud,J. Mark Cock,Christian Dumas,Mohammed Bendahmane +6 more
TL;DR: A novel petal‐expressed, basic helix‐loop‐helix encoding gene (BIGPETAL, BPE) that is involved in the control of petal size is identified and BPEp is therefore a part of the network that links the patterning genes to final morphogenesis.
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