GENEVESTIGATOR. Arabidopsis Microarray Database and Analysis Toolbox
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TLDR
Genevestigator as mentioned in this paper is a web-browser interface for gene expression analysis using Affymetrix GeneChip data, which allows users to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs.Abstract:
High-throughput gene expression analysis has become a frequent and powerful research tool in biology. At present, however, few software applications have been developed for biologists to query large microarray gene expression databases using a Web-browser interface. We present GENEVESTIGATOR, a database and Web-browser data mining interface for Affymetrix GeneChip data. Users can query the database to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs. Reversely, mining tools allow users to identify genes specifically expressed during selected stresses, growth stages, or in particular organs. Using GENEVESTIGATOR, the gene expression profiles of more than 22,000 Arabidopsis genes can be obtained, including those of 10,600 currently uncharacterized genes. The objective of this software application is to direct gene functional discovery and design of new experiments by providing plant biologists with contextual information on the expression of genes. The database and analysis toolbox is available as a community resource at https://www.genevestigator.ethz.ch.read more
Citations
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Journal ArticleDOI
Geminivirus C3 Protein: Replication Enhancement and Protein Interactions
TL;DR: Investigating the impact of mutations to amino acids that are conserved across the C3 protein family on replication enhancement and protein interactions in dicot-infecting geminivirus replication established the importance of C3-C3, C2-C1, and C4-PCNA interactions in geminIVirus replication.
Journal ArticleDOI
Characterization of Mitochondrial Alternative NAD(P)H Dehydrogenases in Arabidopsis: Intraorganelle Location and Expression
TL;DR: NDA1 plays a role in integrating metabolic activities of chloroplasts and mitochondria, and NDA2, NDB2 and Aox1a were up-regulated in a coordinated manner under various treatments, potentially forming a complete respiratory chain capable of oxidizing matrix and cytosolic NAD(P)H.
Journal ArticleDOI
Two alternatively spliced isoforms of the Arabidopsis SR45 protein have distinct roles during normal plant development.
Xiao-Ning Zhang,Stephen M. Mount +1 more
TL;DR: This study provides evidence that the two alternatively spliced isoforms of SR45 have distinct biological functions and tests the ability of each SR45 isoform to complement the sr45-1 mutant by overexpression of isoform-specific green fluorescent protein (GFP) fusion proteins.
Journal ArticleDOI
Genes of the most conserved WOX clade in plants affect root and flower development in Arabidopsis
Yves Deveaux,Claire Toffano-Nioche,Gaëlle Claisse,Vincent Thareau,Halima Morin,Patrick Laufs,Hervé Moreau,Martin Kreis,Alain Lecharny +8 more
TL;DR: Evidence is provided in favor of the WOX13 OG as the clade containing the most conserved WOX genes and established a functional link to organ initiation and development in Arabidopsis, most likely by preventing premature differentiation.
Journal ArticleDOI
Patterning the axis in plants: auxin in control
Ive De Smet,Gerd Jürgens +1 more
TL;DR: Very recent findings suggest a general mechanism of branching triggered by local accumulation of auxin in a 'zone of competence' at the margin of stem-cell systems.
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