GENEVESTIGATOR. Arabidopsis Microarray Database and Analysis Toolbox
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TLDR
Genevestigator as mentioned in this paper is a web-browser interface for gene expression analysis using Affymetrix GeneChip data, which allows users to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs.Abstract:
High-throughput gene expression analysis has become a frequent and powerful research tool in biology. At present, however, few software applications have been developed for biologists to query large microarray gene expression databases using a Web-browser interface. We present GENEVESTIGATOR, a database and Web-browser data mining interface for Affymetrix GeneChip data. Users can query the database to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs. Reversely, mining tools allow users to identify genes specifically expressed during selected stresses, growth stages, or in particular organs. Using GENEVESTIGATOR, the gene expression profiles of more than 22,000 Arabidopsis genes can be obtained, including those of 10,600 currently uncharacterized genes. The objective of this software application is to direct gene functional discovery and design of new experiments by providing plant biologists with contextual information on the expression of genes. The database and analysis toolbox is available as a community resource at https://www.genevestigator.ethz.ch.read more
Citations
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Journal ArticleDOI
The C-Terminal Variable Region Specifies the Dynamic Properties of Arabidopsis Microtubule-Associated Protein MAP65 Isotypes
Andrei Smertenko,Despina Kaloriti,Hsin-Yu Chang,Jindriska Fiserova,Jindriska Fiserova,Zdenek Opatrny,Patrick J. Hussey +6 more
TL;DR: The microtubule-associated protein, MAP65, is a member of a family of divergent microtubules-associated proteins from different organisms generally involved in maintaining the integrity of the central spindle in mitosis as mentioned in this paper.
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Improving crop disease resistance: lessons from research on Arabidopsis and tomato
TL;DR: Examples of how knowledge from models can be transferred to economically important crops resulting in new tools to enable and accelerate classical plant breeding are described.
Journal ArticleDOI
The Anaphase-Promoting Complex Is a Dual Integrator That Regulates Both MicroRNA-Mediated Transcriptional Regulation of Cyclin B1 and Degradation of Cyclin B1 during Arabidopsis Male Gametophyte Development
TL;DR: APC/C is an integrator that regulates both microRNA-mediated transcriptional regulation of CYCB1;1 and degradation of CY CB 1;1, and the percentage of mature pollen with no or single sperm-like cells increased in apc/c mutants and plants overexpressing APC8 partially mimicked the duo1 phenotype.
Journal ArticleDOI
Combating stress with flavodoxin: a promising route for crop improvement
Matias D. Zurbriggen,Vanesa B. Tognetti,Vanesa B. Tognetti,María F. Fillat,Mohammad-Reza Hajirezaei,Estela M. Valle,Néstor Carrillo +6 more
TL;DR: Transgenic lines showed wide-range tolerance to drought, chilling, oxidants, heat and iron starvation, which makes this novel strategy a potentially powerful biotechnological tool for the generation of multiple-tolerant crops in the near future.
Journal ArticleDOI
The Arabidopsis downy mildew resistance gene RPP8 is induced by pathogens and salicylic acid and is regulated by W box cis elements.
Toni J. Mohr,Nicole D. Mammarella,Troy Hoff,Bonnie J. Woffenden,John G. Jelesko,John M. McDowell +5 more
TL;DR: Results indicate that WRKY transcription factors can regulate expression of surveillance genes at the top of the defense-signaling cascade, particularly under defense-inducing conditions.
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