GENEVESTIGATOR. Arabidopsis Microarray Database and Analysis Toolbox
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TLDR
Genevestigator as mentioned in this paper is a web-browser interface for gene expression analysis using Affymetrix GeneChip data, which allows users to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs.Abstract:
High-throughput gene expression analysis has become a frequent and powerful research tool in biology. At present, however, few software applications have been developed for biologists to query large microarray gene expression databases using a Web-browser interface. We present GENEVESTIGATOR, a database and Web-browser data mining interface for Affymetrix GeneChip data. Users can query the database to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs. Reversely, mining tools allow users to identify genes specifically expressed during selected stresses, growth stages, or in particular organs. Using GENEVESTIGATOR, the gene expression profiles of more than 22,000 Arabidopsis genes can be obtained, including those of 10,600 currently uncharacterized genes. The objective of this software application is to direct gene functional discovery and design of new experiments by providing plant biologists with contextual information on the expression of genes. The database and analysis toolbox is available as a community resource at https://www.genevestigator.ethz.ch.read more
Citations
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Journal ArticleDOI
Light induces peroxisome proliferation in Arabidopsis seedlings through the photoreceptor phytochrome A, the transcription factor HY5 HOMOLOG, and the peroxisomal protein PEROXIN11b.
Mintu Desai,Jianping Hu +1 more
TL;DR: It is demonstrated that the phyA and hyh mutants exhibit reduced peroxisome abundance, a phenotype that can be rescued by overexpressing PEX11b in these plants, and it is concluded that HYH and P EX11b constitute a novel branch of thephyA-mediated light signaling cascade, which promotes peroxISome proliferation during seedling photomorphogenesis.
Journal ArticleDOI
The Arabidopsis-mei2-Like genes play a role in meiosis and vegetative growth in Arabidopsis
TL;DR: Functional analysis using RNA interference and combinations of insertion alleles revealed a role for the AML genes in meiosis, with RNAi lines and specific multiple mutant combinations displaying sterility and a range of defects in meiotic chromosome behavior.
Book Series
Signaling and Communication in Plants.
TL;DR: This chapter ventures to give a survey on the role of auxin as a coordinative signal that regulates patterning of cell differentiation, cell division and cell expansion in the totipotent plant cells.
Journal ArticleDOI
Transcriptomic Analysis of the Role of Carboxylic Acids in Metabolite Signaling in Arabidopsis Leaves
Iris Finkemeier,Ann-Christine König,William Heard,Adriano Nunes-Nesi,Phuong Anh Pham,Dario Leister,Alisdair R. Fernie,Lee J. Sweetlove +7 more
TL;DR: The results suggest that changes in carboxylic acid abundances can be perceived and signaled in Arabidopsis (Arabidopsis thaliana) by as yet unknown signaling pathways.
Journal ArticleDOI
Interactions between the Cell Cycle and Embryonic Patterning in Arabidopsis Uncovered by a Mutation in DNA Polymerase ε
TL;DR: The results uncover an interaction between the cell cycle and the processes that determine cell fate during plant embryogenesis as well as the role of DNA polymerase inhibitor aphidicolin in this process.
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