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GENEVESTIGATOR. Arabidopsis Microarray Database and Analysis Toolbox

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TLDR
Genevestigator as mentioned in this paper is a web-browser interface for gene expression analysis using Affymetrix GeneChip data, which allows users to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs.
Abstract
High-throughput gene expression analysis has become a frequent and powerful research tool in biology. At present, however, few software applications have been developed for biologists to query large microarray gene expression databases using a Web-browser interface. We present GENEVESTIGATOR, a database and Web-browser data mining interface for Affymetrix GeneChip data. Users can query the database to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs. Reversely, mining tools allow users to identify genes specifically expressed during selected stresses, growth stages, or in particular organs. Using GENEVESTIGATOR, the gene expression profiles of more than 22,000 Arabidopsis genes can be obtained, including those of 10,600 currently uncharacterized genes. The objective of this software application is to direct gene functional discovery and design of new experiments by providing plant biologists with contextual information on the expression of genes. The database and analysis toolbox is available as a community resource at https://www.genevestigator.ethz.ch.

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Roles of cell wall peroxidases in plant development

TL;DR: Each CIII Prx isoform could have specific functions in muro and this could explain the conservation of a high number of genes in plant genomes.
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Analysis of the Arabidopsis IRX9/IRX9-L and IRX14/IRX14-L pairs of glycosyltransferase genes reveals critical contributions to biosynthesis of the hemicellulose glucuronoxylan

TL;DR: Two new genes from Arabidopsis (Arabidopsis thaliana) are identified and analyzed that encode glycosyltransferase family 43 members proposed to function during xylan backbone elongation and reveal two distinct sets of four genes each differentially contributing to GX biosynthesis.
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Histone H2A.Z and homologues of components of the SWR1 complex are required to control immunity in Arabidopsis

TL;DR: In this article, the ATP-dependent chromatin remodeling complex SWR1 was found to interact with PIE1 in Arabidopsis, but not canonical H2A histone.
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The Populus Genome Integrative Explorer (PopGenIE): a new resource for exploring the Populus genome

TL;DR: The Populus Genome Integrative Explorer (PopGenIE), an integrated set of tools for exploring the Populus genome and transcriptome, significantly increases accessibility to Populus genomics resources and allows exploration of transcriptomics data without the need to learn or understand complex statistical analysis methods.
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Exploring membrane-associated NAC transcription factors in Arabidopsis: implications for membrane biology in genome regulation

TL;DR: It is proposed that proteolytic activation of MTFs is a genome-wide mechanism regulating plant genomes and the presence of numerous MTFS is predicted in the whole transcription factors in plants.
References
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Journal ArticleDOI

Gene Ontology: tool for the unification of biology

TL;DR: The goal of the Gene Ontology Consortium is to produce a dynamic, controlled vocabulary that can be applied to all eukaryotes even as knowledge of gene and protein roles in cells is accumulating and changing.
Journal ArticleDOI

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

TL;DR: The Gene Expression Omnibus (GEO) project was initiated in response to the growing demand for a public repository for high-throughput gene expression data and provides a flexible and open design that facilitates submission, storage and retrieval of heterogeneous data sets from high-power gene expression and genomic hybridization experiments.
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Analysis of the genome sequence of the flowering plant Arabidopsis thaliana.

TL;DR: This is the first complete genome sequence of a plant and provides the foundations for more comprehensive comparison of conserved processes in all eukaryotes, identifying a wide range of plant-specific gene functions and establishing rapid systematic ways to identify genes for crop improvement.
PatentDOI

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Journal ArticleDOI

Hierarchical Organization of Modularity in Metabolic Networks

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