GENEVESTIGATOR. Arabidopsis Microarray Database and Analysis Toolbox
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TLDR
Genevestigator as mentioned in this paper is a web-browser interface for gene expression analysis using Affymetrix GeneChip data, which allows users to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs.Abstract:
High-throughput gene expression analysis has become a frequent and powerful research tool in biology. At present, however, few software applications have been developed for biologists to query large microarray gene expression databases using a Web-browser interface. We present GENEVESTIGATOR, a database and Web-browser data mining interface for Affymetrix GeneChip data. Users can query the database to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs. Reversely, mining tools allow users to identify genes specifically expressed during selected stresses, growth stages, or in particular organs. Using GENEVESTIGATOR, the gene expression profiles of more than 22,000 Arabidopsis genes can be obtained, including those of 10,600 currently uncharacterized genes. The objective of this software application is to direct gene functional discovery and design of new experiments by providing plant biologists with contextual information on the expression of genes. The database and analysis toolbox is available as a community resource at https://www.genevestigator.ethz.ch.read more
Citations
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Journal ArticleDOI
Embryogenesis - the humble beginnings of plant life.
TL;DR: This review addresses early embryo development, highlighting general mechanisms and crucial regulators that are involved in patterning the embryo and were mainly analysed in the post-genome decade.
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Differential Regulation of the Expression of Two High-Affinity Sulfate Transporters, SULTR1.1 and SULTR1.2, in Arabidopsis
Hatem Rouached,Markus Wirtz,Remi Alary,Rüdiger Hell,A. Bulak Arpat,Jean-Claude Davidian,Pierre Fourcroy,Pierre Berthomieu +7 more
TL;DR: It is hypothesized that interplay between SULTR1.1 and SUL TR1.2 transporters could be an important mechanism to regulate sulfate content in the roots and depends on different regulatory networks.
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The Essential Nature of Sphingolipids in Plants as Revealed by the Functional Identification and Characterization of the Arabidopsis LCB1 Subunit of Serine Palmitoyltransferase
TL;DR: It is demonstrated that plant SPT is a heteromeric enzyme and that sphingolipids are essential components of plant cells and contribute to growth and development.
Journal ArticleDOI
The CHD3 Chromatin Remodeler PICKLE and Polycomb Group Proteins Antagonistically Regulate Meristem Activity in the Arabidopsis Root
Ernst Aichinger,Ernst Aichinger,Corina B. R. Villar,Riccardo Di Mambro,Sabrina Sabatini,Claudia Köhler,Claudia Köhler +6 more
TL;DR: It is reported that the chromatin remodeling factor PICKLE (PKL) and the PcG protein CURLY LEAF (CLF) antagonistically determineRoot meristem activity is largely controlled by the antagonistic activity of P cG proteins and PKL.
Journal ArticleDOI
Phosphatidylinositol 4,5-Bisphosphate Influences PIN Polarization by Controlling Clathrin-Mediated Membrane Trafficking in Arabidopsis
Till Ischebeck,Stephanie Werner,Stephanie Werner,Praveen Krishnamoorthy,Jennifer Lerche,Jennifer Lerche,Mónica Meijón,Irene Stenzel,Irene Stenzel,Christian Löfke,Theresa Wiessner,Yang Ju Im,Imara Y. Perera,Tim Iven,Ivo Feussner,Wolfgang Busch,Wendy F. Boss,Thomas Teichmann,Bettina Hause,Staffan Persson,Ingo Heilmann,Ingo Heilmann +21 more
TL;DR: In this article, two related PI4P 5-kinases, PIP5K1 and PIP 5K2, were found to have abnormal, partially apolar distribution in Arabidopsis thaliana.
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