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GENEVESTIGATOR. Arabidopsis Microarray Database and Analysis Toolbox

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TLDR
Genevestigator as mentioned in this paper is a web-browser interface for gene expression analysis using Affymetrix GeneChip data, which allows users to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs.
Abstract
High-throughput gene expression analysis has become a frequent and powerful research tool in biology. At present, however, few software applications have been developed for biologists to query large microarray gene expression databases using a Web-browser interface. We present GENEVESTIGATOR, a database and Web-browser data mining interface for Affymetrix GeneChip data. Users can query the database to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs. Reversely, mining tools allow users to identify genes specifically expressed during selected stresses, growth stages, or in particular organs. Using GENEVESTIGATOR, the gene expression profiles of more than 22,000 Arabidopsis genes can be obtained, including those of 10,600 currently uncharacterized genes. The objective of this software application is to direct gene functional discovery and design of new experiments by providing plant biologists with contextual information on the expression of genes. The database and analysis toolbox is available as a community resource at https://www.genevestigator.ethz.ch.

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The Arabidopsis Mitogen-Activated Protein Kinase Kinase MKK3 Is Upstream of Group C Mitogen-Activated Protein Kinases and Participates in Pathogen Signaling

TL;DR: In this article, the function of the group B MAPK kinase, MKK3, was analyzed in Arabidopsis thaliana and showed that it plays a role in pathogen defense and further underscore the importance and complexity of MAPK signaling in plant stress responses.
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TCP14 and TCP15 affect internode length and leaf shape in Arabidopsis.

TL;DR: It is shown that mutants in two related class I TCP genes display a range of growth-related phenotypes, consistent with their dynamic expression patterns; these phenotypes are enhanced in the double mutant.
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Glycolate Oxidase Modulates Reactive Oxygen Species–Mediated Signal Transduction during Nonhost Resistance in Nicotiana benthamiana and Arabidopsis

TL;DR: It is shown that GOX is an alternative source for the production of H2O2 during both gene-for-gene and nonhost resistance responses and plays a crucial role during both genes from different defense signal transduction cascades.
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Infection with virulent and avirulent P. syringae strains differentially affects photosynthesis and sink metabolism in Arabidopsis leaves

TL;DR: The regulation of marker genes for source/sink relations and the activities of invertase isoenzymes showed qualitative differences between both interactions, and major differences between the responses to both strains were evident in the onset and time course of changes.
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Functional Analysis of a Predicted Flavonol Synthase Gene Family in Arabidopsis

TL;DR: This study showed that the other expressed AtFLS sequences have tissue- and cell type-specific promoter activities that overlap with those of At FLAVONOL SYNTHASE1 and encode proteins that interact with other flavonoid enzymes in yeast two-hybrid assays, suggesting that these “pseudogenes” have alternative, noncatalytic functions that have not yet been uncovered.
References
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Journal ArticleDOI

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Journal ArticleDOI

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