GENEVESTIGATOR. Arabidopsis Microarray Database and Analysis Toolbox
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TLDR
Genevestigator as mentioned in this paper is a web-browser interface for gene expression analysis using Affymetrix GeneChip data, which allows users to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs.Abstract:
High-throughput gene expression analysis has become a frequent and powerful research tool in biology. At present, however, few software applications have been developed for biologists to query large microarray gene expression databases using a Web-browser interface. We present GENEVESTIGATOR, a database and Web-browser data mining interface for Affymetrix GeneChip data. Users can query the database to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs. Reversely, mining tools allow users to identify genes specifically expressed during selected stresses, growth stages, or in particular organs. Using GENEVESTIGATOR, the gene expression profiles of more than 22,000 Arabidopsis genes can be obtained, including those of 10,600 currently uncharacterized genes. The objective of this software application is to direct gene functional discovery and design of new experiments by providing plant biologists with contextual information on the expression of genes. The database and analysis toolbox is available as a community resource at https://www.genevestigator.ethz.ch.read more
Citations
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Journal ArticleDOI
The Lateral Organ Boundaries Domain Transcription Factor LBD20 Functions in Fusarium Wilt Susceptibility and Jasmonate Signaling in Arabidopsis
TL;DR: LBD20 is a F. oxysporum susceptibility gene that appears to regulate components of JA signaling downstream of COI1 and MYC2 that are required for full elicitation of F. oxide- and JA-dependent responses.
Journal ArticleDOI
Functional redundancy in the Arabidopsis Cathepsin B gene family contributes to basal defence, the hypersensitive response and senescence
Hazel McLellan,Hazel McLellan,Eleanor M. Gilroy,Byung-Wook Yun,Paul R. J. Birch,Paul R. J. Birch,Gary J. Loake +6 more
TL;DR: A redundant function for AtCathB genes in basal defence as well as a potential regulatory role in distinct forms of plant PCD are demonstrated.
Journal ArticleDOI
MADS-complexes regulate transcriptome dynamics during pollen maturation
Wim Verelst,David Twell,Stefan de Folter,Stefan de Folter,Richard G. H. Immink,Heinz Saedler,Thomas Münster +6 more
TL;DR: This work has identified the pollen-specific MIKC* class of MADS-domain transcription factors as major regulators of transcriptome dynamics during male reproductive cell development in Arabidopsis thaliana and uncovered part of the underlying network.
Journal ArticleDOI
A subcellular localization compendium of hydrogen peroxide‐induced proteins
Annelies Inzé,Sandy Vanderauwera,Frank A. Hoeberichts,Michaël Vandorpe,Tim Van Gaever,Frank Van Breusegem +5 more
TL;DR: The mapping of the subcellular localization of H( 2)O(2) -induced proteins paves the way for future research to unravel the H(2]O (2) responses in plants.
Journal ArticleDOI
Plant VAP27 proteins: domain characterization, intracellular localization and role in plant development
Pengwei Wang,Christine Richardson,Timothy J. Hawkins,Imogen Sparkes,Chris Hawes,Patrick J. Hussey +5 more
TL;DR: Data indicate that VAP27 proteins used at EPCSs are essential for normal ER-cytoskeleton interaction and for plant development.
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