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GENEVESTIGATOR. Arabidopsis Microarray Database and Analysis Toolbox

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TLDR
Genevestigator as mentioned in this paper is a web-browser interface for gene expression analysis using Affymetrix GeneChip data, which allows users to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs.
Abstract
High-throughput gene expression analysis has become a frequent and powerful research tool in biology. At present, however, few software applications have been developed for biologists to query large microarray gene expression databases using a Web-browser interface. We present GENEVESTIGATOR, a database and Web-browser data mining interface for Affymetrix GeneChip data. Users can query the database to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs. Reversely, mining tools allow users to identify genes specifically expressed during selected stresses, growth stages, or in particular organs. Using GENEVESTIGATOR, the gene expression profiles of more than 22,000 Arabidopsis genes can be obtained, including those of 10,600 currently uncharacterized genes. The objective of this software application is to direct gene functional discovery and design of new experiments by providing plant biologists with contextual information on the expression of genes. The database and analysis toolbox is available as a community resource at https://www.genevestigator.ethz.ch.

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Characterization of two Arabidopsis thaliana glutathione S-transferases

TL;DR: RT-PCR analysis was used to evaluate the expression of the two genes in response to treatment with herbicides and safeners, chemicals, low and high temperature, and revealed that AtGSTU26 is induced by the chloroacetanilide herbicides alachlor and metolachors and the safener benoxacor, and after exposure to low temperatures, while AtG STF9 seems not to be influenced by the treatments employed.
Journal ArticleDOI

EMBRYONIC FACTOR 1 encodes an AMP deaminase and is essential for the zygote to embryo transition in Arabidopsis

TL;DR: During somatic embryogenesis, a high level of FAC1 expression was observed in developing embryos including putative embryogenic cells, suggesting one of the earliest expressed genes known in plants may act through AMP depletion to provide sufficient energy for the zygote to proceed through development.
Journal ArticleDOI

Identification of genes involved in the ACC-mediated control of root cell elongation in **Arabidopsis thaliana**

TL;DR: ACC interferes with cell elongation in the Arabidopsis thaliana roots by inhibiting cells from entering the elongation process and by immediately stimulating the formation of cross-links in cell wall components, diminishing the remaining elongation capacity.
Journal ArticleDOI

Identification of an Arabidopsis Plasma Membrane–Located ATP Transporter Important for Anther Development

TL;DR: A mitochondrial carrier family type ATP transporter located in the plant plasma membrane is identified as a candidate transporter able to mediate ATP export and may serve as an extracellular signal required for anther dehiscence and is a novel factor critical for pollination and autogamy.
References
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Journal ArticleDOI

Gene Ontology: tool for the unification of biology

TL;DR: The goal of the Gene Ontology Consortium is to produce a dynamic, controlled vocabulary that can be applied to all eukaryotes even as knowledge of gene and protein roles in cells is accumulating and changing.
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Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

TL;DR: The Gene Expression Omnibus (GEO) project was initiated in response to the growing demand for a public repository for high-throughput gene expression data and provides a flexible and open design that facilitates submission, storage and retrieval of heterogeneous data sets from high-power gene expression and genomic hybridization experiments.
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Analysis of the genome sequence of the flowering plant Arabidopsis thaliana.

TL;DR: This is the first complete genome sequence of a plant and provides the foundations for more comprehensive comparison of conserved processes in all eukaryotes, identifying a wide range of plant-specific gene functions and establishing rapid systematic ways to identify genes for crop improvement.
PatentDOI

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Journal ArticleDOI

Hierarchical Organization of Modularity in Metabolic Networks

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