scispace - formally typeset
Open AccessJournal ArticleDOI

GENEVESTIGATOR. Arabidopsis Microarray Database and Analysis Toolbox

Reads0
Chats0
TLDR
Genevestigator as mentioned in this paper is a web-browser interface for gene expression analysis using Affymetrix GeneChip data, which allows users to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs.
Abstract
High-throughput gene expression analysis has become a frequent and powerful research tool in biology. At present, however, few software applications have been developed for biologists to query large microarray gene expression databases using a Web-browser interface. We present GENEVESTIGATOR, a database and Web-browser data mining interface for Affymetrix GeneChip data. Users can query the database to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs. Reversely, mining tools allow users to identify genes specifically expressed during selected stresses, growth stages, or in particular organs. Using GENEVESTIGATOR, the gene expression profiles of more than 22,000 Arabidopsis genes can be obtained, including those of 10,600 currently uncharacterized genes. The objective of this software application is to direct gene functional discovery and design of new experiments by providing plant biologists with contextual information on the expression of genes. The database and analysis toolbox is available as a community resource at https://www.genevestigator.ethz.ch.

read more

Content maybe subject to copyright    Report

Citations
More filters
Journal ArticleDOI

Genome-wide analysis reveals gene expression and metabolic network dynamics during embryo development in Arabidopsis

TL;DR: Methods to isolate whole live Arabidopsis (Arabidopsis thaliana) embryos as young as zygote and perform genome-wide profiling of gene expression have generated comprehensive gene expression data sets for embryo development in Arabidops and may serve as an important foundational resource for other seed plants.
Journal ArticleDOI

The PEROXIN11 protein family controls peroxisome proliferation in Arabidopsis.

TL;DR: It is concluded that all five Arabidopsis PEX11 proteins promote peroxisome proliferation and that individual family members play specific roles in distinctPeroxisomal subtypes and environmental conditions and possibly in different steps of peroxISome proliferation.
Journal ArticleDOI

RACK1 mediates multiple hormone responsiveness and developmental processes in Arabidopsis

TL;DR: Results provide the first genetic evidence that RACK1A is involved in multiple signal transduction pathways and mediates hormone responses and plays a regulatory role in multiple developmental processes.
Journal ArticleDOI

Plant methionine sulfoxide reductase A and B multigenic families.

TL;DR: It is reported that some MSR genes display organ-specific expression patterns and that those encoding plastidic MSRs are highly expressed in photosynthetic organs and it is shown that the expression of numerousMSR genes is enhanced by environmental conditions known to generate oxidative stress.
Journal ArticleDOI

Proteome Dynamics during Plastid Differentiation in Rice

TL;DR: Early light-induced changes during chloroplast development of rice (Oryza sativa) chloroplasts were examined, and the transition from heterotrophic metabolism to photosynthesis-supported autOTrophic metabolism was already detectable 2 h after illumination and affected most essential metabolic modules.
References
More filters
Journal ArticleDOI

Gene Ontology: tool for the unification of biology

TL;DR: The goal of the Gene Ontology Consortium is to produce a dynamic, controlled vocabulary that can be applied to all eukaryotes even as knowledge of gene and protein roles in cells is accumulating and changing.
Journal ArticleDOI

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

TL;DR: The Gene Expression Omnibus (GEO) project was initiated in response to the growing demand for a public repository for high-throughput gene expression data and provides a flexible and open design that facilitates submission, storage and retrieval of heterogeneous data sets from high-power gene expression and genomic hybridization experiments.
Journal ArticleDOI

Analysis of the genome sequence of the flowering plant Arabidopsis thaliana.

TL;DR: This is the first complete genome sequence of a plant and provides the foundations for more comprehensive comparison of conserved processes in all eukaryotes, identifying a wide range of plant-specific gene functions and establishing rapid systematic ways to identify genes for crop improvement.
PatentDOI

Expression monitoring by hybridization to high density oligonucleotide arrays

TL;DR: In this article, the authors proposed a method for monitoring the expression levels of a multiplicity of genes by hybridizing a nucleic acid sample to a high density array of oligonucleotide probes and quantifying the hybridized nucleic acids in the array.
Journal ArticleDOI

Hierarchical Organization of Modularity in Metabolic Networks

TL;DR: It is shown that the metabolic networks of 43 distinct organisms are organized into many small, highly connected topologic modules that combine in a hierarchical manner into larger, less cohesive units, with their number and degree of clustering following a power law.
Related Papers (5)