scispace - formally typeset
Open AccessJournal ArticleDOI

GENEVESTIGATOR. Arabidopsis Microarray Database and Analysis Toolbox

Reads0
Chats0
TLDR
Genevestigator as mentioned in this paper is a web-browser interface for gene expression analysis using Affymetrix GeneChip data, which allows users to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs.
Abstract
High-throughput gene expression analysis has become a frequent and powerful research tool in biology. At present, however, few software applications have been developed for biologists to query large microarray gene expression databases using a Web-browser interface. We present GENEVESTIGATOR, a database and Web-browser data mining interface for Affymetrix GeneChip data. Users can query the database to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs. Reversely, mining tools allow users to identify genes specifically expressed during selected stresses, growth stages, or in particular organs. Using GENEVESTIGATOR, the gene expression profiles of more than 22,000 Arabidopsis genes can be obtained, including those of 10,600 currently uncharacterized genes. The objective of this software application is to direct gene functional discovery and design of new experiments by providing plant biologists with contextual information on the expression of genes. The database and analysis toolbox is available as a community resource at https://www.genevestigator.ethz.ch.

read more

Content maybe subject to copyright    Report

Citations
More filters
Journal ArticleDOI

Genetic analysis of two Arabidopsis DNA polymerase epsilon subunits during early embryogenesis

TL;DR: In this paper, the role of DNA polymerase e during gametophyte and seed development using forward and reverse genetic approaches was investigated in Arabidopsis, where the catalytic subunit of this complex is encoded by two genes, AtPOL2a and AtDP2b, whereas the second largest regulatory subunit AtDPB2 is present as a unique complete copy.
Journal ArticleDOI

Genome-wide analysis of the GH3 family in apple (Malus × domestica).

TL;DR: This study indicated that some GH3 genes were significantly induced in M. sieversii after various phytohormone and abiotic stress treatments, and that ABA, SA, salt, and cold treatments reduce the endogenous level of axuin.
Journal ArticleDOI

Mutation of Arabidopsis BARD1 Causes Meristem Defects by Failing to Confine WUSCHEL Expression to the Organizing Center

TL;DR: It is suggested that BARD1 regulates SAM organization and maintenance by limiting WUS expression to the organizing center and either full-length Bard1 or a clone that encoded the C-terminal domain was sufficient to complement the bard1-3 phenotype.
Journal ArticleDOI

Characterization of a small auxin-up RNA (SAUR)-like gene involved in Arabidopsis thaliana development.

TL;DR: The root of Arabidopsis thaliana is used as a model system to unravel the molecular nature of cell elongation and its arrest and it is concluded that the expression of SAUR76 is mainly regulated by the increase in auxin that results from the addition of ACC, rather than by ACC itself.
References
More filters
Journal ArticleDOI

Gene Ontology: tool for the unification of biology

TL;DR: The goal of the Gene Ontology Consortium is to produce a dynamic, controlled vocabulary that can be applied to all eukaryotes even as knowledge of gene and protein roles in cells is accumulating and changing.
Journal ArticleDOI

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

TL;DR: The Gene Expression Omnibus (GEO) project was initiated in response to the growing demand for a public repository for high-throughput gene expression data and provides a flexible and open design that facilitates submission, storage and retrieval of heterogeneous data sets from high-power gene expression and genomic hybridization experiments.
Journal ArticleDOI

Analysis of the genome sequence of the flowering plant Arabidopsis thaliana.

TL;DR: This is the first complete genome sequence of a plant and provides the foundations for more comprehensive comparison of conserved processes in all eukaryotes, identifying a wide range of plant-specific gene functions and establishing rapid systematic ways to identify genes for crop improvement.
PatentDOI

Expression monitoring by hybridization to high density oligonucleotide arrays

TL;DR: In this article, the authors proposed a method for monitoring the expression levels of a multiplicity of genes by hybridizing a nucleic acid sample to a high density array of oligonucleotide probes and quantifying the hybridized nucleic acids in the array.
Journal ArticleDOI

Hierarchical Organization of Modularity in Metabolic Networks

TL;DR: It is shown that the metabolic networks of 43 distinct organisms are organized into many small, highly connected topologic modules that combine in a hierarchical manner into larger, less cohesive units, with their number and degree of clustering following a power law.
Related Papers (5)