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GENEVESTIGATOR. Arabidopsis Microarray Database and Analysis Toolbox

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TLDR
Genevestigator as mentioned in this paper is a web-browser interface for gene expression analysis using Affymetrix GeneChip data, which allows users to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs.
Abstract
High-throughput gene expression analysis has become a frequent and powerful research tool in biology. At present, however, few software applications have been developed for biologists to query large microarray gene expression databases using a Web-browser interface. We present GENEVESTIGATOR, a database and Web-browser data mining interface for Affymetrix GeneChip data. Users can query the database to retrieve the expression patterns of individual genes throughout chosen environmental conditions, growth stages, or organs. Reversely, mining tools allow users to identify genes specifically expressed during selected stresses, growth stages, or in particular organs. Using GENEVESTIGATOR, the gene expression profiles of more than 22,000 Arabidopsis genes can be obtained, including those of 10,600 currently uncharacterized genes. The objective of this software application is to direct gene functional discovery and design of new experiments by providing plant biologists with contextual information on the expression of genes. The database and analysis toolbox is available as a community resource at https://www.genevestigator.ethz.ch.

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ERF105 is a transcription factor gene of Arabidopsis thaliana required for freezing tolerance and cold acclimation

TL;DR: ERF105 is a novel cold-regulated transcription factor gene of Arabidopsis that makes a significant contribution to freezing tolerance and cold acclimation and the expression of cold-responsive genes in erf105 mutants suggests that its action is linked to the CBF regulon mediating cold responses.
Journal ArticleDOI

Differential gene expression profiles of the mitochondrial respiratory components in illuminated Arabidopsis leaves.

TL;DR: A mechanistic model of respiratory gene expression in illuminated leaves is proposed, suggesting that modulations of cellular carbon status by elevated photosynthesis are involved in respiratory gene Expression.
Journal ArticleDOI

Identification of a novel group of putative Arabidopsis thaliana beta-(1,3)-galactosyltransferases.

TL;DR: A bioinformatic/molecular study of CAZy GT-family-31 confirmed that 20 members of the GT-31 family contained domains/motifs typical of biochemically characterised β-(1,3)-GTs from mammalian systems and likely candidates for the assembly of the ubiquitously found AGPs.
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Polyamines in response to abiotic stress tolerance through transgenic approaches

TL;DR: How PAs in higher plants act during environmental stress and how transgenic strategies have improved the understanding of the molecular mechanisms at play are highlighted.
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Cytokinin-induced changes in CLAVATA1 and WUSCHEL expression temporally coincide with altered floral development in Arabidopsis

TL;DR: The temporal coincidence of aberrant floral phenotype with changes in transcript levels of CLV1 and WUS suggests that cytokinins regulate flower development through genes controlling shoot apical meristem activity.
References
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Journal ArticleDOI

Gene Ontology: tool for the unification of biology

TL;DR: The goal of the Gene Ontology Consortium is to produce a dynamic, controlled vocabulary that can be applied to all eukaryotes even as knowledge of gene and protein roles in cells is accumulating and changing.
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Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

TL;DR: The Gene Expression Omnibus (GEO) project was initiated in response to the growing demand for a public repository for high-throughput gene expression data and provides a flexible and open design that facilitates submission, storage and retrieval of heterogeneous data sets from high-power gene expression and genomic hybridization experiments.
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Analysis of the genome sequence of the flowering plant Arabidopsis thaliana.

TL;DR: This is the first complete genome sequence of a plant and provides the foundations for more comprehensive comparison of conserved processes in all eukaryotes, identifying a wide range of plant-specific gene functions and establishing rapid systematic ways to identify genes for crop improvement.
PatentDOI

Expression monitoring by hybridization to high density oligonucleotide arrays

TL;DR: In this article, the authors proposed a method for monitoring the expression levels of a multiplicity of genes by hybridizing a nucleic acid sample to a high density array of oligonucleotide probes and quantifying the hybridized nucleic acids in the array.
Journal ArticleDOI

Hierarchical Organization of Modularity in Metabolic Networks

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