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Open AccessJournal ArticleDOI

Genomic predictors of the maximal O2 uptake response to standardized exercise training programs

TLDR
These genomic predictors of the response of Vo(2max) to regular exercise provide new targets for the study of the biology of fitness and its adaptation to regular Exercise.
Abstract
Low cardiorespiratory fitness is a powerful predictor of morbidity and cardiovascular mortality. In 473 sedentary adults, all whites, from 99 families of the Health, Risk Factors, Exercise Training...

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Individual and combined associations between cardiorespiratory fitness and grip strength with common mental disorders: a prospective cohort study in the UK Biobank.

TL;DR: Ass associations between individual and combined markers of cardiorespiratory fitness and grip strength with the incidence of common mental disorders are examined in a 7-year prospective cohort study in 152,978 UK Biobank participants.
Journal ArticleDOI

Genomics in rugby union: A review and future prospects

TL;DR: The RugbyGene project is a multi-institutional research collaboration in rugby union that will perform molecular genetic analyses of varying complexity that could become useful tools for rugby practitioners in the future and provide complementary and additional information to that provided by the non-genetic tests currently used.
Journal ArticleDOI

Genetic influences on physical activity in young adults: a twin study.

TL;DR: The results suggest that genetic factors contribute significantly to physical activity levels in young adults and that sports activity is under stronger genetic influence than leisure time physical activity excluding sports and physical activity at work does not seem to be associated with sports activities or other leisure timephysical activity at this age.
Journal ArticleDOI

The Beneficial Effects of Physical Activity: Is It Down to Your Genes? A Systematic Review and Meta-Analysis of Twin and Family Studies.

TL;DR: Shared familial factors, including genetics, are likely to be a significant contributor to the response of body composition and cardiorespiratory fitness following PA.
References
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Book

Physical Activity And Health: A Report Of The Surgeon General

TL;DR: This report is the first report of the Surgeon General on physical activity and health, and strong evidence is shown to indicate that regular physical activity will provide clear and substantial health gains.
Journal ArticleDOI

Common SNPs explain a large proportion of the heritability for human height

TL;DR: Evidence is provided that the remaining heritability is due to incomplete linkage disequilibrium between causal variants and genotyped SNPs, exacerbated by causal variants having lower minor allele frequency than the SNPs explored to date.
Journal ArticleDOI

Changes in Physical Fitness and All-Cause Mortality: A Prospective Study of Healthy and Unhealthy Men

TL;DR: Men who maintained or improved adequate physical fitness were less likely to die from all causes and from cardiovascular disease during follow-up than persistently unfit men.
Journal ArticleDOI

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

Benjamin F. Voight, +183 more
- 01 Jul 2010 - 
TL;DR: By combining genome-wide association data from 8,130 individuals with type 2 diabetes and 38,987 controls of European descent and following up previously unidentified meta-analysis signals, 12 new T2D association signals are identified with combined P < 5 × 10−8.
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