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Open AccessJournal ArticleDOI

The ABCD study: understanding the development of risk for mental and physical health outcomes.

Nicole R. Karcher, +1 more
- 01 Jan 2021 - 
- Vol. 46, Iss: 1, pp 131-142
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TLDR
How the Adolescent Brain Cognitive Development Study was designed to elucidate factors associated with the development of negative mental and physical health outcomes is outlined and a selective overview of results emerging from the ABCD Study is provided.
About
This article is published in Neuropsychopharmacology.The article was published on 2021-01-01 and is currently open access. It has received 109 citations till now. The article focuses on the topics: Mental health & Population.

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Challenges and solutions to measurement of neurocognitive mechanisms in developmental settings.

TL;DR: In this paper , the authors outline methodological shortcomings that explain why widely used task-based measures of neurocognition currently tell us little about mental health risk, and discuss specific challenges that arise when studying neurocognitive mechanisms in developmental settings, and share suggestions for overcoming them.
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12. Neural Circuit Markers of Familial Risk for Depression Among Healthy Youth in the Adolescent Brain Cognitive Development (ABCD) Study

TL;DR: In this article , the authors identify functional connectivity patterns associated with familial risk for depression in youth at familial risk of depression but who do not currently exhibit symptoms, and identify robust and replicable findings using a limited number of studies and small sample sizes.
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Association of Racial Discrimination With Adiposity in Children and Adolescents

TL;DR: The authors assesses the association of self-reported experiences of racial discrimination with adiposity in a large sample of children and adolescents in the US, and find that the association is positively associated with perceived racial discrimination.
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Shared molecular genetic factors influence subcortical brain morphometry and Parkinson’s disease risk

TL;DR: In this article , the authors identify genes and molecular pathways underlying the associations between Parkinson's disease and the volume of ten brain structures measured through magnetic resonance imaging (MRI) scans and find significant positive genetic correlations between PD and intracranial and subcortical brain volumes.
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The prospective relationship between weight-based discrimination and eating pathology among youth.

TL;DR: In this article , the authors assessed prospective associations between weight-based discrimination and eating pathology among participants in the Adolescent Brain Cognitive Development Study and found that the presence of weightbased discrimination may confer additional risk for the onset of disordered eating.
References
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Journal ArticleDOI

Power failure: why small sample size undermines the reliability of neuroscience

TL;DR: It is shown that the average statistical power of studies in the neurosciences is very low, and the consequences include overestimates of effect size and low reproducibility of results.
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Brain development during childhood and adolescence: a longitudinal MRI study.

TL;DR: This large-scale longitudinal pediatric neuroimaging study confirmed linear increases in white matter, but demonstrated nonlinear changes in cortical gray matter, with a preadolescent increase followed by a postadolescent decrease.
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A multi-modal parcellation of human cerebral cortex

TL;DR: Using multi-modal magnetic resonance images from the Human Connectome Project and an objective semi-automated neuroanatomical approach, 180 areas per hemisphere are delineated bounded by sharp changes in cortical architecture, function, connectivity, and/or topography in a precisely aligned group average of 210 healthy young adults.
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The life course as developmental theory.

TL;DR: The pioneering longitudinal studies of child development were extended well beyond childhood and eventually followed their young study members up to the middle years and later life, generating issues that could not be addressed satisfactorily by available theories.
Related Papers (5)

Image processing and analysis methods for the Adolescent Brain Cognitive Development Study.

Donald J. Hagler, +144 more
- 15 Nov 2019 -