The ABCD study: understanding the development of risk for mental and physical health outcomes.
Nicole R. Karcher,M Deanna +1 more
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TLDR
How the Adolescent Brain Cognitive Development Study was designed to elucidate factors associated with the development of negative mental and physical health outcomes is outlined and a selective overview of results emerging from the ABCD Study is provided.About:
This article is published in Neuropsychopharmacology.The article was published on 2021-01-01 and is currently open access. It has received 109 citations till now. The article focuses on the topics: Mental health & Population.read more
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Socioeconomic resources are associated with distributed alterations of the brain’s intrinsic functional architecture in youth
Chandra Sripada,Arianna M. Gard,Mike Angstadt,Aman Taxali,Tristan Greathouse,Katherine McCurry,Luke W. Hyde,Alexander Weigard,Peter Walczyk,Mary M. Heitzeg +9 more
TL;DR: In this article , the authors examined resting state functional connectivity patterns from 5821 youth in the Adolescent Brain Cognitive Development (ABCD) study, employing multivariate methods across three levels: whole-brain, network-wise, and connection-wise.
Posted ContentDOI
Connectomic Alterations Linked to Transdiagnostic Risk for Psychopathology at the Transition to Adolescence
Chandra Sripada,Mike Angstadt,Saige Rutherford,Aman Taxali,Tristan Greathouse,D. Angus Clark,Luke W. Hyde,Alexander Weigard,Sarah J. Brislin,Brian M. Hicks,Mary M. Heitzeg +10 more
TL;DR: The general factor of psychopathology is associated with connectomic alterations involving control networks and default mode network and brain imaging combined with network neuroscience can identify distributed and generalizable signatures of transdiagnostic risk for psychopathology during emerging adolescence.
Posted ContentDOI
Connectomes for 40,000 UK Biobank participants: A multi-modal, multi-scale brain network resource
TL;DR: In this article , structural and functional connectomes for multiple parcellation granularities, several alternative measures of interregional connectivity, and a variety of common data pre-processing techniques, yielding more than one million connectomes in total and requiring more than 200,000 hours of compute time.
Journal ArticleDOI
Resting-State Functional Connectivity between Putamen and Salience Network and Childhood Body Mass Index
Shervin Assari,Shanika Boyce +1 more
TL;DR: In this paper, the authors explored racial and socioeconomic status differences in the associations between putamen functional connectivity to the salience network and children's body mass index (BMI) in the Adolescent Brain Cognitive Development (ABCD) study.
Journal ArticleDOI
Cohort studies in child and adolescent psychiatry
Nathalie E. Holz,Frauke Nees,Frauke Nees,Andreas Meyer-Lindenberg,Heike Tost,H. Hölling,Thomas Keil,Thomas Keil,Daniel Brandeis,Marcel Romanos,Tobias Banaschewski +10 more
TL;DR: Kohortenstudien mit frühem Beginn und Lebensspannenperspektive sind essenziell, um die Verläufe psychiatrischer Erkrankungen sowie deren Risiko- and Resilienzfaktoren zu beleuchten werden, wird dargestellt and exemplarisch die Mannheimer Risikokinderstudie.
References
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UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age
Cathie Sudlow,John Gallacher,Naomi E. Allen,Valerie Beral,Paul Burton,John Danesh,Paul Downey,Paul Elliott,Jane Green,Martin J Landray,Bette Liu,Paul M. Matthews,Giok Ong,Jill P. Pell,Alan J. Silman,Alan Young,Tim Sprosen,Tim Peakman,Rory Collins +18 more
TL;DR: The UK Biobank is described, a large population-based prospective study, established to allow investigation of the genetic and non-genetic determinants of the diseases of middle and old age.
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Power failure: why small sample size undermines the reliability of neuroscience
Katherine S. Button,John P. A. Ioannidis,Claire Mokrysz,Brian A. Nosek,Jonathan Flint,Emma S J Robinson,Marcus R. Munafò +6 more
TL;DR: It is shown that the average statistical power of studies in the neurosciences is very low, and the consequences include overestimates of effect size and low reproducibility of results.
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Brain development during childhood and adolescence: a longitudinal MRI study.
Jay N. Giedd,Jonathan D. Blumenthal,Neal Jeffries,F X Castellanos,Hong Liu,Alex P. Zijdenbos,Tomáš Paus,Alan C. Evans,Judith L. Rapoport +8 more
TL;DR: This large-scale longitudinal pediatric neuroimaging study confirmed linear increases in white matter, but demonstrated nonlinear changes in cortical gray matter, with a preadolescent increase followed by a postadolescent decrease.
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A multi-modal parcellation of human cerebral cortex
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TL;DR: The pioneering longitudinal studies of child development were extended well beyond childhood and eventually followed their young study members up to the middle years and later life, generating issues that could not be addressed satisfactorily by available theories.
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