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Open AccessJournal ArticleDOI

The ABCD study: understanding the development of risk for mental and physical health outcomes.

Nicole R. Karcher, +1 more
- 01 Jan 2021 - 
- Vol. 46, Iss: 1, pp 131-142
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TLDR
How the Adolescent Brain Cognitive Development Study was designed to elucidate factors associated with the development of negative mental and physical health outcomes is outlined and a selective overview of results emerging from the ABCD Study is provided.
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This article is published in Neuropsychopharmacology.The article was published on 2021-01-01 and is currently open access. It has received 109 citations till now. The article focuses on the topics: Mental health & Population.

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Citations
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Predicting the future of neuroimaging predictive models in mental health

TL;DR: In this paper , the authors aim to accelerate the utility and applications of neuroimaging-based predictive models for psychiatric research by highlighting and considering these topics, such as bias and fairness, the handling of dirty data, and interpretable models.
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Symptom-Based Profiling and Multimodal Neuroimaging of a Large Preteenage Population Identifies Distinct Obsessive-Compulsive Disorder–like Subtypes With Neurocognitive Differences

TL;DR: This article identified two subgroups with contrasting patterns in internalized and externalized dimensions of OCD, suggesting that anxiety is not its major predisposing factor, and their results may have implications for the nosology and treatment of preteenage OCD.
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Neural impacts of stigma, racism, and discrimination.

TL;DR: In this article , the effects of stigma and discrimination emerge early in life and have long-term consequences, such as negative life experiences and discrimination are taken into account, which can contribute to physical health disparities in minoritized and marginalized groups.
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A simple permutation-based test of intermodal correspondence.

TL;DR: This article used subject-level data and a classical permutation testing framework to test and assess similarities between brain maps, which is comparable to traditional permutation tests in that it involves randomly permuting subjects to generate a null distribution of intermodal correspondence statistics, which they compare to an observed statistic to estimate a p-value.
Journal ArticleDOI

Symptom-Based Profiling and Multimodal Neuroimaging of a Large Preteenage Population Identifies Distinct Obsessive-Compulsive Disorder–like Subtypes With Neurocognitive Differences

TL;DR: The authors identified two subgroups with contrasting patterns in internalized and externalized dimensions of OCD, suggesting that anxiety is not its major predisposing factor, and showed that OCD symptoms are heterogeneous at the level of symptom clustering and its underlying neural basis.
References
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Journal ArticleDOI

Power failure: why small sample size undermines the reliability of neuroscience

TL;DR: It is shown that the average statistical power of studies in the neurosciences is very low, and the consequences include overestimates of effect size and low reproducibility of results.
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Brain development during childhood and adolescence: a longitudinal MRI study.

TL;DR: This large-scale longitudinal pediatric neuroimaging study confirmed linear increases in white matter, but demonstrated nonlinear changes in cortical gray matter, with a preadolescent increase followed by a postadolescent decrease.
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A multi-modal parcellation of human cerebral cortex

TL;DR: Using multi-modal magnetic resonance images from the Human Connectome Project and an objective semi-automated neuroanatomical approach, 180 areas per hemisphere are delineated bounded by sharp changes in cortical architecture, function, connectivity, and/or topography in a precisely aligned group average of 210 healthy young adults.
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The life course as developmental theory.

TL;DR: The pioneering longitudinal studies of child development were extended well beyond childhood and eventually followed their young study members up to the middle years and later life, generating issues that could not be addressed satisfactorily by available theories.
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Image processing and analysis methods for the Adolescent Brain Cognitive Development Study.

Donald J. Hagler, +144 more
- 15 Nov 2019 -