Understanding of dopant-induced osteogenesis and angiogenesis in calcium phosphate ceramics
TLDR
This review highlights the use of trace elements in CaP biomaterials, and offers an insight into the mechanisms of how metal ions can enhance both osteogenesis and angiogenesis.About:
This article is published in Trends in Biotechnology.The article was published on 2013-10-01 and is currently open access. It has received 387 citations till now.read more
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Synthesis, Characterization, Functionalization and Bio-Applications of Hydroxyapatite Nanomaterials: An Overview
TL;DR: An overview of hydroxyapatite (HA) nanomaterials with the provision of future directions is given in this article , highlighting the chemical composition, recent progress in synthesis methods, characterization and surface modification methods, ion-doping, and role in biomedical applications.
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Does Local Application of Strontium Increase Osteogenesis and Biomaterial Osteointegration in Osteoporotic and Other Bone Tissue Conditions: Review of Literature
TL;DR: An overview about strontium, its mechanisms of action in bone tissue and initiated changes of bone remodeling within biomaterials is provided.
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The Potential Role of Lithium as an Antiviral Agent against SARS-CoV-2 via Membrane Depolarization: Review and Hypothesis
TL;DR: The hypothesis states that lithium can suppress NOD-like receptor family pyrin domain containing-3 (NLRP3) inflammasome activity, inhibit cell death, and exhibit immunomodulation via membrane depolarization, and these effects are presumed to improve the morbidity and mortality of COVID-19 patients.
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Novel Nanostructured Zn-substituted Monetite Based Biomaterial for Bone Regeneration
S. Padilla,Arcadio García de Castro,Ana Garzon-Gutierrez,Lorena Benito,Silvia Enciso,Maria Canillas,G Carrodeguas +6 more
TL;DR: In vivo evaluation showed the effectiveness of the material to regenerate and to maintain 89 ± 9% of the volume of a critical size bone defect in sheep at 16 weeks and the newly formed bone showed abundant vascularization and osteogenic activity.
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Encapsulation of Calcium Phosphates on Electrospun Nanofibers for Tissue Engineering Applications
TL;DR: In this paper, a broad overview of CaP material-incorporated electrospun nanocomposite fibers and their possible applications in tissue engineering is provided, and the future perspectives of this interesting and emerging composite material fabricated via electrospinning is discussed.
References
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Lisa M. Gaetke,Ching Kuang Chow +1 more
TL;DR: Results obtained from available animal studies suggest that the compound is protective, and further studies are needed to better understand the cellular effects of this essential, but potentially toxic, trace mineral and its functional interaction with other nutrients.
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TL;DR: Current understanding of the mechanisms by which WNT signalng regulates bone homeostasis is reviewed, finding the pathway is now the target for therapeutic intervention to restore bone strength in millions of patients at risk for fracture.
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The Effects of Strontium Ranelate on the Risk of Vertebral Fracture in Women with Postmenopausal Osteoporosis
Pierre J. Meunier,Christian Roux,Ego Seeman,Sergio Ortolani,J. Badurski,Tim D. Spector,J. Cannata,Adam Balogh,EM Lemmel,S. Pors-Nielsen,René Rizzoli,Harry K. Genant,Jean-Yves Reginster +12 more
TL;DR: Treatment of postmenopausal osteoporosis with strontium ranelate leads to early and sustained reductions in the risk of vertebral fractures.
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Ionic products of bioactive glass dissolution increase proliferation of human osteoblasts and induce insulin-like growth factor II mRNA expression and protein synthesis.
TL;DR: It is suggested that the stimulatory effect of the ionic products of Bioglass 45S5 dissolution on osteoblast proliferation may be mediated by IGF-II.
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Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: A review
Susmita Bose,Solaiman Tarafder +1 more
TL;DR: This review highlights some of the current drug and growth factor delivery approaches and critical issues using CaP particles, coatings, cements, and scaffolds towards orthopedic and dental applications.