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Open AccessJournal ArticleDOI

Understanding of dopant-induced osteogenesis and angiogenesis in calcium phosphate ceramics

TLDR
This review highlights the use of trace elements in CaP biomaterials, and offers an insight into the mechanisms of how metal ions can enhance both osteogenesis and angiogenesis.
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This article is published in Trends in Biotechnology.The article was published on 2013-10-01 and is currently open access. It has received 387 citations till now.

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Journal ArticleDOI

Fabrication and Characterization of Nano-TCP Doped with Various Ions for Bone Implant Applications

TL;DR: In this paper, a precipitation procedure was applied for synthesizing pure and doped tri-calcium phosphates, which were sintered at 1100°C for one hour.
Journal ArticleDOI

Barley phytochemicals and health promoting benefits: A comprehensive review

TL;DR: Barley is one of the most important cereal crops cultivated in all agricultural regions across the world as mentioned in this paper and it is high in proteins, and carbohydrates, including Beta-glucan, lipids, vitamins, and minerals.
Journal ArticleDOI

Layer-by-layer self-assembly and clinical application in orthopedics

TL;DR: In this paper , the authors introduce the basic principle and the development of layer-by-layer (LbL) in orthopaedics, review and analyze the chemical strategy of LbL in the preparation of bone implants to ensure the stability of the implant, and introduce the use of lbL bone implants in Orthopaedic in recent years.
Book ChapterDOI

Angiogenesis induction by bioactive glasses and glass-ceramics

TL;DR: In this article , all categories of BGs, including silicate-, phosphate-, and borate-based glasses, were evaluated and successfully doped with proangiogenic elements.
References
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Journal ArticleDOI

Copper toxicity, oxidative stress, and antioxidant nutrients.

TL;DR: Results obtained from available animal studies suggest that the compound is protective, and further studies are needed to better understand the cellular effects of this essential, but potentially toxic, trace mineral and its functional interaction with other nutrients.
Journal ArticleDOI

WNT signaling in bone homeostasis and disease: from human mutations to treatments

TL;DR: Current understanding of the mechanisms by which WNT signalng regulates bone homeostasis is reviewed, finding the pathway is now the target for therapeutic intervention to restore bone strength in millions of patients at risk for fracture.
Journal ArticleDOI

Ionic products of bioactive glass dissolution increase proliferation of human osteoblasts and induce insulin-like growth factor II mRNA expression and protein synthesis.

TL;DR: It is suggested that the stimulatory effect of the ionic products of Bioglass 45S5 dissolution on osteoblast proliferation may be mediated by IGF-II.
Journal ArticleDOI

Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: A review

TL;DR: This review highlights some of the current drug and growth factor delivery approaches and critical issues using CaP particles, coatings, cements, and scaffolds towards orthopedic and dental applications.
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