Understanding of dopant-induced osteogenesis and angiogenesis in calcium phosphate ceramics
TLDR
This review highlights the use of trace elements in CaP biomaterials, and offers an insight into the mechanisms of how metal ions can enhance both osteogenesis and angiogenesis.About:
This article is published in Trends in Biotechnology.The article was published on 2013-10-01 and is currently open access. It has received 387 citations till now.read more
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Enhanced sinterability and in vitro bioactivity of barium-doped akermanite ceramic
TL;DR: In this article, the influence of substituting barium (Ba2+) ions on the structural, mechanical and in vitro biological properties of akermanite prepared via high-energy wet planetary ball milling and sintering was reported.
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The Role of Growth Factors in Bioactive Coatings.
Dragana Bjelić,Matjaž Finšgar +1 more
TL;DR: The incorporation of growth factors in a bioactive coating represents a novel approach in bone tissue engineering, in which osteoinduction is enhanced in order to create the optimal conditions for the bone healing process, which crucially affects implant fixation as discussed by the authors.
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Self Setting Bone Cement Formulations Based on Egg shell Derived TetraCalcium Phosphate BioCeramics
TL;DR: In this article, the authors have demonstrated the advantages of eggshell derived tetra calcium phosphate (ETTCP) in bone cement formulations due to the presence of biologically relevant ions such as Mg2+, Sr2+, SiO2-4, F-, K+ and Na+ ions in the cement properties.
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Enhanced dielectric constant and structural transformation in Fe-doped hydroxyapatite synthesized by wet chemical method
TL;DR: In this paper, the synthesis of single-phase Fe-doped hydroxyapatite (HAp) [Ca10−xFe 9.9Fe 0.1 and 0.3] was reported.
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ZnO modified 1393 bioactive scaffolds with enhanced cytocompatibility and mechanical performance
TL;DR: Results illustrate minimal cell lysis, significant increase in cellular metabolic activity, cytocompatibility, and physico-mechanical properties and enhancement in biomineralization and cellular attachments for the zinc derived 1393 scaffolds in comparison with the parent glass scaffold making ZnO derived scaffolds a suitable candidate for neo-bone tissue regenerative or reconstructive application.
References
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Lisa M. Gaetke,Ching Kuang Chow +1 more
TL;DR: Results obtained from available animal studies suggest that the compound is protective, and further studies are needed to better understand the cellular effects of this essential, but potentially toxic, trace mineral and its functional interaction with other nutrients.
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TL;DR: Current understanding of the mechanisms by which WNT signalng regulates bone homeostasis is reviewed, finding the pathway is now the target for therapeutic intervention to restore bone strength in millions of patients at risk for fracture.
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The Effects of Strontium Ranelate on the Risk of Vertebral Fracture in Women with Postmenopausal Osteoporosis
Pierre J. Meunier,Christian Roux,Ego Seeman,Sergio Ortolani,J. Badurski,Tim D. Spector,J. Cannata,Adam Balogh,EM Lemmel,S. Pors-Nielsen,René Rizzoli,Harry K. Genant,Jean-Yves Reginster +12 more
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Ionic products of bioactive glass dissolution increase proliferation of human osteoblasts and induce insulin-like growth factor II mRNA expression and protein synthesis.
TL;DR: It is suggested that the stimulatory effect of the ionic products of Bioglass 45S5 dissolution on osteoblast proliferation may be mediated by IGF-II.
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Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: A review
Susmita Bose,Solaiman Tarafder +1 more
TL;DR: This review highlights some of the current drug and growth factor delivery approaches and critical issues using CaP particles, coatings, cements, and scaffolds towards orthopedic and dental applications.