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Open AccessJournal ArticleDOI

Understanding of dopant-induced osteogenesis and angiogenesis in calcium phosphate ceramics

TLDR
This review highlights the use of trace elements in CaP biomaterials, and offers an insight into the mechanisms of how metal ions can enhance both osteogenesis and angiogenesis.
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This article is published in Trends in Biotechnology.The article was published on 2013-10-01 and is currently open access. It has received 387 citations till now.

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Optimally dosed nanoceria attenuates osteoarthritic degeneration of joint cartilage and subchondral bone

TL;DR: The nanoceria treatment profoundly reduced the degenerative symptoms including cellular apoptosis and the secretion of catabolic proteins and pro-inflammatory cytokines while boosting regenerative events such as the polarization of M2 macrophages and the production of anti- inflammatory cytokines and chondrogenic glycoproteins.
Journal ArticleDOI

Calcium Phosphate Based Bioactive Ceramic Layers on Implant Materials Preparation, Properties, and Biological Performance

Monika Furko, +1 more
- 25 Aug 2020 - 
TL;DR: In this paper, the authors compared the morphological, chemical, and biological properties of calcium phosphate based bioactive ceramics (CPCs) prepared by the pulse current electrochemical method.
Journal ArticleDOI

Rare earth-based materials for bone regeneration: Breakthroughs and advantages

TL;DR: A comprehensive review of the breakthroughs and advantages of rare earth (RE)-based bone regeneration materials is provided in this paper , where challenges and prospects for rare earth-based biomaterials are discussed.
Book ChapterDOI

Ceramic devices for bone regeneration: Mechanical and clinical issues and new perspectives

TL;DR: In this article, a personalized approach based on tissue engineering in association with the implementation and development of versatile additive manufacturing technologies appears very promising achievement of this approach must be based on the use of cell mechanics and growth in the design of "bioinstructive" ceramic scaffolds.
References
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Journal ArticleDOI

Copper toxicity, oxidative stress, and antioxidant nutrients.

TL;DR: Results obtained from available animal studies suggest that the compound is protective, and further studies are needed to better understand the cellular effects of this essential, but potentially toxic, trace mineral and its functional interaction with other nutrients.
Journal ArticleDOI

WNT signaling in bone homeostasis and disease: from human mutations to treatments

TL;DR: Current understanding of the mechanisms by which WNT signalng regulates bone homeostasis is reviewed, finding the pathway is now the target for therapeutic intervention to restore bone strength in millions of patients at risk for fracture.
Journal ArticleDOI

Ionic products of bioactive glass dissolution increase proliferation of human osteoblasts and induce insulin-like growth factor II mRNA expression and protein synthesis.

TL;DR: It is suggested that the stimulatory effect of the ionic products of Bioglass 45S5 dissolution on osteoblast proliferation may be mediated by IGF-II.
Journal ArticleDOI

Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: A review

TL;DR: This review highlights some of the current drug and growth factor delivery approaches and critical issues using CaP particles, coatings, cements, and scaffolds towards orthopedic and dental applications.
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