Understanding of dopant-induced osteogenesis and angiogenesis in calcium phosphate ceramics
TLDR
This review highlights the use of trace elements in CaP biomaterials, and offers an insight into the mechanisms of how metal ions can enhance both osteogenesis and angiogenesis.About:
This article is published in Trends in Biotechnology.The article was published on 2013-10-01 and is currently open access. It has received 387 citations till now.read more
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Biofunctional Ionic-Doped Calcium Phosphates: Silk Fibroin Composites for Bone Tissue Engineering Scaffolding.
Sandra Pina,Raphaël F. Canadas,Gema Jiménez,Macarena Perán,Juan A. Marchal,Rui L. Reis,J. M. Oliveira +6 more
TL;DR: Novel biofunctional scaffolds for bone regeneration composed of silk fibroin and β-tricalcium phosphate and incorporating Sr, Zn, and Mn are presented, indicating that biofunctional ionic-doped composite scaffolds are good candidates for further in vivo studies on bone tissue regeneration.
Journal ArticleDOI
Biofunctional Elements Incorporated Nano/Microstructured Coatings on Titanium Implants with Enhanced Osteogenic and Antibacterial Performance.
TL;DR: In this review, recent advances in biofunctional element-incorporated nano/microstructured coatings on Ti and Ti alloy implants are described and the prospects and limitations are discussed.
Journal ArticleDOI
Cu2 +, Co2 + and Cr3 + doping of a calcium phosphate cement influences materials properties and response of human mesenchymal stromal cells
Martha Schamel,Anne Bernhardt,Mandy Quade,Claudia Würkner,Uwe Gbureck,Claus Moseke,Michael Gelinsky,Anja Lode +7 more
TL;DR: Cell culture experiments with human mesenchymal stromal cells indicated that the observed cell response is not only influenced by the releasedMetal ions but also by changed cement properties, in addition to the effect of released metal ions by changing properties of the ceramic matrix.
Journal ArticleDOI
Composite nanoclay-hydroxyapatite-polymer fiber scaffolds for bone tissue engineering manufactured using pressurized gyration
TL;DR: A novel fabrication of polymer composite fibers using polycaprolactone, montmorillonite nanoclay, and nano-hydroxyapatite-clay for bone tissue engineering applications demonstrated that the polymer fiber scaffolds are biocompatible, and the cells were able to thrive and differentiate on the Fiber scaffolds.
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Effects of magnesium silicate on the mechanical properties, biocompatibility, bioactivity, degradability, and osteogenesis of poly(butylene succinate)-based composite scaffolds for bone repair
TL;DR: The results demonstrated that the bioactive m-MS/PBSu composite scaffolds with good biocompatibility, degradability, bioactivity and osteogenesis are promising biomaterials for bone repair.
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TL;DR: This review highlights some of the current drug and growth factor delivery approaches and critical issues using CaP particles, coatings, cements, and scaffolds towards orthopedic and dental applications.