Understanding of dopant-induced osteogenesis and angiogenesis in calcium phosphate ceramics
TLDR
This review highlights the use of trace elements in CaP biomaterials, and offers an insight into the mechanisms of how metal ions can enhance both osteogenesis and angiogenesis.About:
This article is published in Trends in Biotechnology.The article was published on 2013-10-01 and is currently open access. It has received 387 citations till now.read more
Citations
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Journal ArticleDOI
Injectable osteogenic and angiogenic nanocomposite hydrogels for irregular bone defects.
M. Vishnu Priya,A Sivshanmugam,Aldo R. Boccaccini,Ourania-Menti Goudouri,Wook Sun,Nathaniel S. Hwang,S. Deepthi,Shantikumar V. Nair,Rangasamy Jayakumar +8 more
TL;DR: Hydrogels containing MBG showed early initiation of differentiation and higher expression of alkaline phosphatase and osteocalcin confirming the osteoinductive property of MBG indicate that this composite hydrogel can be used for regenerating irregular bone defects.
Journal ArticleDOI
Monodisperse photoluminescent and highly biocompatible bioactive glass nanoparticles for controlled drug delivery and cell imaging
TL;DR: The results suggest the great potential of BGN-Eu as multifunctional bioactive nanomaterials for cell imaging and bone tissue regeneration applications.
Book ChapterDOI
Ion substitution in biological and synthetic apatites
TL;DR: This chapter reviews the main characteristics of biological apatites, with particular focus on the associated foreign ions, and of synthetic HA, with particularly emphasis on the structural and chemical modifications induced by ionic substitution.
Journal ArticleDOI
Magnesium-organic framework-based stimuli-responsive systems that optimize the bone microenvironment for enhanced bone regeneration
TL;DR: Remarkable in vivo functional bone regeneration was achieved with an in situ bone island pattern formed internally, suggesting that the biomaterials replicating the developmental process can be an attractive strategy for enhancing tissue regeneration.
Journal ArticleDOI
DNA adsorbed on hydroxyapatite surfaces
Luis J. del Valle,Oscar Bertran,Gustavo Chaves,Guillermo Revilla-López,Manuel Rivas,María Teresa Casas,Jordi Casanovas,Pau Turon,Jordi Puiggalí,Carlos Alemán +9 more
TL;DR: The results indicate that the DNA secondary structure is perfectly preserved on the (001) surface, this stability being accompanied by an attractive binding energy, and although the termination of the (010) surface with PO4 3- and Ca2+ ions also deforms the double helix, it forms very strong attractive interactions with the biomolecule.
References
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Ionic products of bioactive glass dissolution increase proliferation of human osteoblasts and induce insulin-like growth factor II mRNA expression and protein synthesis.
TL;DR: It is suggested that the stimulatory effect of the ionic products of Bioglass 45S5 dissolution on osteoblast proliferation may be mediated by IGF-II.
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Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: A review
Susmita Bose,Solaiman Tarafder +1 more
TL;DR: This review highlights some of the current drug and growth factor delivery approaches and critical issues using CaP particles, coatings, cements, and scaffolds towards orthopedic and dental applications.