scispace - formally typeset
Open AccessJournal ArticleDOI

Understanding of dopant-induced osteogenesis and angiogenesis in calcium phosphate ceramics

TLDR
This review highlights the use of trace elements in CaP biomaterials, and offers an insight into the mechanisms of how metal ions can enhance both osteogenesis and angiogenesis.
About
This article is published in Trends in Biotechnology.The article was published on 2013-10-01 and is currently open access. It has received 387 citations till now.

read more

Citations
More filters
Dissertation

Enhanced osseointegration of endoprostheses using selective laser sintered porous titanium alloy combined with solution deposited coatings

A. S. Mumith
TL;DR: The hypothesis can be accepted and novel electrochemically coated laser sintered porous collars may provide a viable alternative ingrowth region to enhance the osseointegration of massive bone tumour endoprostheses.
Journal ArticleDOI

Using DFT to Calculate the Parameters of the Crystal Field in Mn2+ Doped Hydroxyapatite Crystals

TL;DR: In this paper, the crystal field parameters for two nonequivalent positions Ca (I) and Ca (II) for hydroxyapatite (HAp) crystals from the density functional theory (DFT) are calculated.
Journal ArticleDOI

Preparation and evaluation of osteoinductive porous biphasic calcium phosphate granules obtained from eggshell for bone tissue engineering

TL;DR: In this paper , a pore former and sintering procedure was used to obtain porous biphasic calcium phosphate granules (EBGs) for bone grafts, and the EBGs were found to have high biocompatibility and no cytotoxicity.
Journal ArticleDOI

Chemical imaging of the reconstruction of new bone and trace elements inside bioactive glass scaffolds in vivo: a multimodal and quantitative micro-ion beam analysis

TL;DR: In this paper, an original multimodal analysis is proposed for follow-up of bone regeneration inside a SiO2-CaO bioactive glass scaffold in vivo, which highlights subtle differences in mineralization and distinguishes between the mineralized scaffold, the newly formed bone and native bone from the trace metal nutrients content.
Journal ArticleDOI

MgO implanted in rat tibia bone marrow is osteoinductive through the formation of a matrix, containing hydroxyapatite

TL;DR: In this article, the results indicated the formation of hydroxyl-apatite (HA) in the entire intramedullary space after 1 week of wound healing.
References
More filters
Journal ArticleDOI

Copper toxicity, oxidative stress, and antioxidant nutrients.

TL;DR: Results obtained from available animal studies suggest that the compound is protective, and further studies are needed to better understand the cellular effects of this essential, but potentially toxic, trace mineral and its functional interaction with other nutrients.
Journal ArticleDOI

WNT signaling in bone homeostasis and disease: from human mutations to treatments

TL;DR: Current understanding of the mechanisms by which WNT signalng regulates bone homeostasis is reviewed, finding the pathway is now the target for therapeutic intervention to restore bone strength in millions of patients at risk for fracture.
Journal ArticleDOI

Ionic products of bioactive glass dissolution increase proliferation of human osteoblasts and induce insulin-like growth factor II mRNA expression and protein synthesis.

TL;DR: It is suggested that the stimulatory effect of the ionic products of Bioglass 45S5 dissolution on osteoblast proliferation may be mediated by IGF-II.
Journal ArticleDOI

Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: A review

TL;DR: This review highlights some of the current drug and growth factor delivery approaches and critical issues using CaP particles, coatings, cements, and scaffolds towards orthopedic and dental applications.
Related Papers (5)