Understanding of dopant-induced osteogenesis and angiogenesis in calcium phosphate ceramics
TLDR
This review highlights the use of trace elements in CaP biomaterials, and offers an insight into the mechanisms of how metal ions can enhance both osteogenesis and angiogenesis.About:
This article is published in Trends in Biotechnology.The article was published on 2013-10-01 and is currently open access. It has received 387 citations till now.read more
Citations
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Effect of Chemistry on Osteogenesis and Angiogenesis Towards Bone Tissue Engineering Using 3D Printed Scaffolds.
TL;DR: Results show that magnesium and silicon incorporated 3DP TCP scaffolds with multiscale porosity have huge potential for bone tissue repair and regeneration.
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A Magnesium-Enriched 3D Culture System that Mimics the Bone Development Microenvironment for Vascularized Bone Regeneration.
Sihan Lin,Guangzheng Yang,Fei Jiang,Mingliang Zhou,Shi Yin,Yanmei Tang,Tingting Tang,Zhiyuan Zhang,Wenjie Zhang,Xinquan Jiang +9 more
TL;DR: A series of experiments show that the Mg‐enriched microenvironment not only stimulates the osteogenic differentiation of stem cells but also promotes neovascularization, suggesting that biomaterials mimicking the developmental microenvironment might be promising tools to enhance tissue regeneration.
Journal ArticleDOI
Mechanical and biological properties of ZnO, SiO2, and Ag2O doped plasma sprayed hydroxyapatite coating for orthopaedic and dental applications.
TL;DR: Biological relevant metallic oxides of ZnO, SiO2, and Ag2O within a hydroxyapatite coating on titanium deposited using a radio frequency induction plasma spray can be employed for replacement surgeries to lower healing time and enhance osseointegration between implant and host tissue.
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Cobalt-releasing 1393 bioactive glass-derived scaffolds for bone tissue engineering applications
Alexander Hoppe,Bojan Jokić,Djordje Janaćković,Tobias Fey,Peter Greil,Stefan Romeis,Jochen Schmidt,Wolfgang Peukert,Jonathan Lao,Edouard Jallot,Aldo R. Boccaccini +10 more
TL;DR: Detailed insights into the physicochemical reactions occurring at the scaffold-fluid interface were derived from advanced micro-particle-induced X-ray emission/Rutherford backscattering spectrometry analysis, and CoO is shown to act in a concentration-dependent manner as both a network former and a network modifier.
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A mini review focused on the proangiogenic role of silicate ions released from silicon-containing biomaterials:
Khandmaa Dashnyam,Ahmed El-Fiqi,Jennifer O. Buitrago,Roman A. Perez,Roman A. Perez,Jonathan C. Knowles,Jonathan C. Knowles,Hae-Won Kim +7 more
TL;DR: The in vitro and in vivo findings of angiogenesis (and the related bone formation) stimulated by the various types of silicon-containing biomaterials where silicate ions released might play essential roles are highlighted.
References
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TL;DR: This review highlights some of the current drug and growth factor delivery approaches and critical issues using CaP particles, coatings, cements, and scaffolds towards orthopedic and dental applications.