Understanding of dopant-induced osteogenesis and angiogenesis in calcium phosphate ceramics
TLDR
This review highlights the use of trace elements in CaP biomaterials, and offers an insight into the mechanisms of how metal ions can enhance both osteogenesis and angiogenesis.About:
This article is published in Trends in Biotechnology.The article was published on 2013-10-01 and is currently open access. It has received 387 citations till now.read more
Citations
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Bone grafts and biomaterials substitutes for bone defect repair: A review.
Wenhao Wang,Kelvin W.K. Yeung +1 more
TL;DR: The currently available bone grafts and bone substitutes as well as the biological and bio-inorganic factors for the treatments of bone defect are reviewed.
Copper-containing mesoporous bioactive glass scaffolds with multifunctional properties of angiogenesis capacity, osteostimulation and antibacterial activity
TL;DR: It is demonstrated that it is possible to develop multifunctional scaffolds by combining enhanced angiogenesis potential, osteostimulation, and antibacterial properties for the treatment of large bone defects.
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Additive manufacturing of biomaterials.
TL;DR: Key additive manufacturing methods are first introduced followed by AM of different materials, and finally applications of AM in various treatment options are reviewed.
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Bioactive Glasses: Sprouting Angiogenesis in Tissue Engineering
Saeid Kargozar,Francesco Baino,Sepideh Hamzehlou,Sepideh Hamzehlou,Robert G. Hill,Masoud Mozafari +5 more
TL;DR: The salient features, the hurdles that must be overcome, and the hopes and constraints for the development of BGs with improved angiogenetic properties are introduced.
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Biomimetic Materials and Fabrication Approaches for Bone Tissue Engineering.
Hwan Kim,Sivashanmugam Amirthalingam,Seung Hyun Kim,Seung-Hun Lee,Jayakumar Rangasamy,Nathaniel S. Hwang +5 more
TL;DR: In this article, a progress report of biomimetic materials and fabrication approaches that are currently being utilized for biomimic scaffold design are reviewed, including 3D printing methods, for optimal host stem cell infiltration, vascularization, nutrient transfer, and stem cell differentiation.
References
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Barbara Bracci,Paola Torricelli,Silvia Panzavolta,Elisa Boanini,Roberto Giardino,Adriana Bigi +5 more
TL;DR: The results of the investigation performed on the coatings, as well as on the powders precipitated in the absence of the substrates, indicate that both Sr(2+) and Mg( 2+) reduce the extent of precipitation, although they are quantitatively incorporated into the nanocrystalline apatitic phase.
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SiO2 and ZnO dopants in three-dimensionally printed tricalcium phosphate bone tissue engineering scaffolds enhance osteogenesis and angiogenesis in vivo.
Gary Fielding,Susmita Bose +1 more
TL;DR: The findings from this study indicate that the combination of SiO2 and ZnO dopants in TCP may be a viable alternative to introducing osteoinductive properties to CaP materials.
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Redox active metal-induced oxidative stress in biological systems
TL;DR: The role of iron and copper in uncontrolled formation of ROS leading to various human diseases such as cancer, cardiovascular disease, and neurological disorders (Alzheimer's disease and Parkinson's disease) is discussed and a discussion is devoted to the various protective antioxidant networks against the deleterious action of free radicals.