Understanding of dopant-induced osteogenesis and angiogenesis in calcium phosphate ceramics
TLDR
This review highlights the use of trace elements in CaP biomaterials, and offers an insight into the mechanisms of how metal ions can enhance both osteogenesis and angiogenesis.About:
This article is published in Trends in Biotechnology.The article was published on 2013-10-01 and is currently open access. It has received 387 citations till now.read more
Citations
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Bone grafts and biomaterials substitutes for bone defect repair: A review.
Wenhao Wang,Kelvin W.K. Yeung +1 more
TL;DR: The currently available bone grafts and bone substitutes as well as the biological and bio-inorganic factors for the treatments of bone defect are reviewed.
Copper-containing mesoporous bioactive glass scaffolds with multifunctional properties of angiogenesis capacity, osteostimulation and antibacterial activity
TL;DR: It is demonstrated that it is possible to develop multifunctional scaffolds by combining enhanced angiogenesis potential, osteostimulation, and antibacterial properties for the treatment of large bone defects.
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Additive manufacturing of biomaterials.
TL;DR: Key additive manufacturing methods are first introduced followed by AM of different materials, and finally applications of AM in various treatment options are reviewed.
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Bioactive Glasses: Sprouting Angiogenesis in Tissue Engineering
Saeid Kargozar,Francesco Baino,Sepideh Hamzehlou,Sepideh Hamzehlou,Robert G. Hill,Masoud Mozafari +5 more
TL;DR: The salient features, the hurdles that must be overcome, and the hopes and constraints for the development of BGs with improved angiogenetic properties are introduced.
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Biomimetic Materials and Fabrication Approaches for Bone Tissue Engineering.
Hwan Kim,Sivashanmugam Amirthalingam,Seung Hyun Kim,Seung-Hun Lee,Jayakumar Rangasamy,Nathaniel S. Hwang +5 more
TL;DR: In this article, a progress report of biomimetic materials and fabrication approaches that are currently being utilized for biomimic scaffold design are reviewed, including 3D printing methods, for optimal host stem cell infiltration, vascularization, nutrient transfer, and stem cell differentiation.
References
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Calcium Phosphate‐Based Resorbable Ceramics: Influence of MgO, ZnO, and SiO2 Dopants
TL;DR: In this article, the influence of dopants on tricalcium phosphate (TCP) resorbable ceramics with special emphasis toward in vitro strength degradation and cell-materials interactions as a function of time was analyzed.
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Bioactive glass coatings with hydroxyapatite and Bioglass particles on Ti-based implants. 1. Processing.
TL;DR: Enameling, producing excellent glass/metal adhesion with well-attached bioactive particles on the surface, is a promising method of forming reliable and lasting implants which can endure substantial chemical and mechanical stresses.
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Angiogenesis in Calcium Phosphate Scaffolds by Inorganic Copper Ion Release
Jake E. Barralet,Uwe Gbureck,Pamela Habibovic,Elke Vorndran,Catherine Gérard,Charles J. Doillon +5 more
TL;DR: Tissue responses to 3D printed macroporous bioceramic scaffolds implanted in mice that had been loaded with either VEGF or copper sulfate were compared and the potential to accelerate and guide angiogenesis and wound healing by copper ion release without the expense of inductive protein(s).
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High concentrations of magnesium modulate vascular endothelial cell behaviour in vitro.
TL;DR: It is demonstrated that magnesium may have a protective effect against atherosclerosis and could play a role in promoting the growth of collateral vessels in chronic ischemia, and because it induces the synthesis of nitric oxide, this cation could be a helpful tool in hypertension as well as in preventing thrombosis.
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Molecular and biophysical mechanisms regulating hypertrophic differentiation in chondrocytes and mesenchymal stem cells.
TL;DR: Control of hypertrophic differentiation can be exploited both for cartilage repair, where a stable phenotype is desired, but also in bone regeneration, where hypertrophic cartilage could act as a template for endochondral bone formation.