Understanding of dopant-induced osteogenesis and angiogenesis in calcium phosphate ceramics
TLDR
This review highlights the use of trace elements in CaP biomaterials, and offers an insight into the mechanisms of how metal ions can enhance both osteogenesis and angiogenesis.About:
This article is published in Trends in Biotechnology.The article was published on 2013-10-01 and is currently open access. It has received 387 citations till now.read more
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Sintering of Magnesium‐Strontium doped Hydroxyapatite nanocrystals : towards the production of 3D biomimetic bone scaffolds
TL;DR: In this article, thermally stable magnesium-strontium hydroxyapatite (HAMgSr) nanocrystals were synthesized and used for the fabrication of sintered highly porous scaffolds.
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Surface degradation-enabled osseointegrative, angiogenic and antiinfective properties of magnesium-modified acrylic bone cement.
Xiao Lin,Jun Ge,Donglei Wei,Chun Liu,Lili Tan,Huilin Yang,Ke Yang,Huan Zhou,Bin Li,Zong-Ping Luo,Lei Yang +10 more
TL;DR: PMMA/Mg surface-degradable acrylic bone cements that possess enhanced osseointegrative, angiogenic and antiinfective properties that are lacking in the clinically used acrylic bone cement are reported.
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Translation of bone wax and its substitutes: History, clinical status and future directions.
TL;DR: An overview of bone and its substitutes together with evolution of their design criteria is carried out, providing information for the innovation and translation of bone haemostatic agents in the near future.
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In-situ XRD study of the crystal size transition of hydroxyapatite from swine bone
Sandra M. Londoño-Restrepo,Mariana Herrera-Lara,Leon R. Bernal-Alvarez,Eric M. Rivera-Muñoz,Mario E. Rodríguez-García +4 more
TL;DR: In this article, X-ray patterns were obtained every 20°C from 400 to 900°C, with heating rates: 3, 6, and 9°C/min P-HAp was also calcined into a furnace to correlate the morphological properties with in situ measures.
References
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Copper toxicity, oxidative stress, and antioxidant nutrients.
Lisa M. Gaetke,Ching Kuang Chow +1 more
TL;DR: Results obtained from available animal studies suggest that the compound is protective, and further studies are needed to better understand the cellular effects of this essential, but potentially toxic, trace mineral and its functional interaction with other nutrients.
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WNT signaling in bone homeostasis and disease: from human mutations to treatments
Roland Baron,Michaela Kneissel +1 more
TL;DR: Current understanding of the mechanisms by which WNT signalng regulates bone homeostasis is reviewed, finding the pathway is now the target for therapeutic intervention to restore bone strength in millions of patients at risk for fracture.
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The Effects of Strontium Ranelate on the Risk of Vertebral Fracture in Women with Postmenopausal Osteoporosis
Pierre J. Meunier,Christian Roux,Ego Seeman,Sergio Ortolani,J. Badurski,Tim D. Spector,J. Cannata,Adam Balogh,EM Lemmel,S. Pors-Nielsen,René Rizzoli,Harry K. Genant,Jean-Yves Reginster +12 more
TL;DR: Treatment of postmenopausal osteoporosis with strontium ranelate leads to early and sustained reductions in the risk of vertebral fractures.
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Ionic products of bioactive glass dissolution increase proliferation of human osteoblasts and induce insulin-like growth factor II mRNA expression and protein synthesis.
TL;DR: It is suggested that the stimulatory effect of the ionic products of Bioglass 45S5 dissolution on osteoblast proliferation may be mediated by IGF-II.
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Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: A review
Susmita Bose,Solaiman Tarafder +1 more
TL;DR: This review highlights some of the current drug and growth factor delivery approaches and critical issues using CaP particles, coatings, cements, and scaffolds towards orthopedic and dental applications.