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Open AccessJournal ArticleDOI

Understanding of dopant-induced osteogenesis and angiogenesis in calcium phosphate ceramics

TLDR
This review highlights the use of trace elements in CaP biomaterials, and offers an insight into the mechanisms of how metal ions can enhance both osteogenesis and angiogenesis.
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This article is published in Trends in Biotechnology.The article was published on 2013-10-01 and is currently open access. It has received 387 citations till now.

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Journal ArticleDOI

Novel Extrusion-Microdrilling Approach to Fabricate Calcium Phosphate-Based Bioceramic Scaffolds Enabling Fast Bone Regeneration.

TL;DR: This work provides a new strategy to fabricate interconnected bioceramic scaffolds allowing for fast bone regeneration, and the EM-TCP/SrPG scaffolds are promising for efficiently repairing bone defects.
Journal ArticleDOI

Effects of physico-chemical properties of ions-doped hydroxyapatite on adsorption and release performance of doxorubicin as a model anticancer drug

TL;DR: In this paper , the performance of hydroxyapatite (HAp) used as a drug carrier of doxorubicin (DOX), including ion-doping, specific surface area, zeta potential, binding energy, etc.
Book ChapterDOI

Ceramic biomaterials for tissue engineering

TL;DR: In this article, the authors reviewed the range of ceramics currently used in skeletal repair and tissue regeneration and covered the bioinert, bioactive, bio-active and resorbable materials, glasses, and glass-ceramics.
Journal ArticleDOI

Effects of physico-chemical properties of ions-doped hydroxyapatite on adsorption and release performance of doxorubicin as a model anticancer drug

TL;DR: In this paper, the performance of hydroxyapatite (HAp) used as a drug carrier of doxorubicin (DOX), including ion-doping, specific surface area, zeta potential, binding energy, etc.
Journal ArticleDOI

Bioactive glass and glass‐ceramic orbital implants

TL;DR: The surgical techniques used to remove the eye in toto or its content evolved at the same time than the evolution of the orbital implants, and nowadays there are two well‐established main techniques: evisceration which refers to the removal of the contents of the eye while the scleral shell and ocular muscle attachments are spared, and enucleation which is a more radical measure involving the Removal of the whole globe from the orbital socket.
References
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Journal ArticleDOI

Copper toxicity, oxidative stress, and antioxidant nutrients.

TL;DR: Results obtained from available animal studies suggest that the compound is protective, and further studies are needed to better understand the cellular effects of this essential, but potentially toxic, trace mineral and its functional interaction with other nutrients.
Journal ArticleDOI

WNT signaling in bone homeostasis and disease: from human mutations to treatments

TL;DR: Current understanding of the mechanisms by which WNT signalng regulates bone homeostasis is reviewed, finding the pathway is now the target for therapeutic intervention to restore bone strength in millions of patients at risk for fracture.
Journal ArticleDOI

Ionic products of bioactive glass dissolution increase proliferation of human osteoblasts and induce insulin-like growth factor II mRNA expression and protein synthesis.

TL;DR: It is suggested that the stimulatory effect of the ionic products of Bioglass 45S5 dissolution on osteoblast proliferation may be mediated by IGF-II.
Journal ArticleDOI

Calcium phosphate ceramic systems in growth factor and drug delivery for bone tissue engineering: A review

TL;DR: This review highlights some of the current drug and growth factor delivery approaches and critical issues using CaP particles, coatings, cements, and scaffolds towards orthopedic and dental applications.
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