Understanding of dopant-induced osteogenesis and angiogenesis in calcium phosphate ceramics
TLDR
This review highlights the use of trace elements in CaP biomaterials, and offers an insight into the mechanisms of how metal ions can enhance both osteogenesis and angiogenesis.About:
This article is published in Trends in Biotechnology.The article was published on 2013-10-01 and is currently open access. It has received 387 citations till now.read more
Citations
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Bone grafts and biomaterials substitutes for bone defect repair: A review.
Wenhao Wang,Kelvin W.K. Yeung +1 more
TL;DR: The currently available bone grafts and bone substitutes as well as the biological and bio-inorganic factors for the treatments of bone defect are reviewed.
Copper-containing mesoporous bioactive glass scaffolds with multifunctional properties of angiogenesis capacity, osteostimulation and antibacterial activity
TL;DR: It is demonstrated that it is possible to develop multifunctional scaffolds by combining enhanced angiogenesis potential, osteostimulation, and antibacterial properties for the treatment of large bone defects.
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Additive manufacturing of biomaterials.
TL;DR: Key additive manufacturing methods are first introduced followed by AM of different materials, and finally applications of AM in various treatment options are reviewed.
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Bioactive Glasses: Sprouting Angiogenesis in Tissue Engineering
Saeid Kargozar,Francesco Baino,Sepideh Hamzehlou,Sepideh Hamzehlou,Robert G. Hill,Masoud Mozafari +5 more
TL;DR: The salient features, the hurdles that must be overcome, and the hopes and constraints for the development of BGs with improved angiogenetic properties are introduced.
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Biomimetic Materials and Fabrication Approaches for Bone Tissue Engineering.
Hwan Kim,Sivashanmugam Amirthalingam,Seung Hyun Kim,Seung-Hun Lee,Jayakumar Rangasamy,Nathaniel S. Hwang +5 more
TL;DR: In this article, a progress report of biomimetic materials and fabrication approaches that are currently being utilized for biomimic scaffold design are reviewed, including 3D printing methods, for optimal host stem cell infiltration, vascularization, nutrient transfer, and stem cell differentiation.
References
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Biochemical and Morphological Changes Associated with Long Bone Abnormalities in Silicon Deficiency
TL;DR: It is demonstrated that the long bones of cockerels fed a silicon-supplemented basal diet and sacrificed at 4 weeks had a significantly greater amount of articular cartilage and water content as compared with the silicon-deficient group.
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Is Wnt signalling the final common pathway leading to bone formation
Frances Milat,Kong Wah Ng +1 more
TL;DR: The role of the Wnt pathway in osteoblast differentiation as well as the interplay between Wnt signalling and other pathways involved in bone formation are focused on.
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Is the calcium receptor a molecular target for the actions of strontium on bone
TL;DR: An action of this divalent cation on the CaR in bone cells represents one possible mechanism by which strontium ranelate, a new antiosteoporotic drug, exerts it skeletal actions in vivo.
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Dietary magnesium reduction to 25% of nutrient requirement disrupts bone and mineral metabolism in the rat
TL;DR: It is demonstrated that Mg intake of 25% NR in the rat causes lower bone mass which may be related to increased release of substance P and TNFalpha.
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Dietary zinc reduces osteoclast resorption activities and increases markers of osteoblast differentiation, matrix maturation, and mineralization in the long bones of growing rats.
TL;DR: Increased trabecular bone with additional zinc suggests that previous requirement estimates of 15 microg Zn/g diet may not meet nutritional needs for optimal bone development, and overall, the up-regulation of extracellular matrix modeling indexes and concomitant decrease in resorption activities as dietary zinc increased from 2.5 to 30 microg/g provide evidence of one or more physiological roles for zinc in modulating the balance between bone formation and Resorption.