Understanding of dopant-induced osteogenesis and angiogenesis in calcium phosphate ceramics
TLDR
This review highlights the use of trace elements in CaP biomaterials, and offers an insight into the mechanisms of how metal ions can enhance both osteogenesis and angiogenesis.About:
This article is published in Trends in Biotechnology.The article was published on 2013-10-01 and is currently open access. It has received 387 citations till now.read more
Citations
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Bone grafts and biomaterials substitutes for bone defect repair: A review.
Wenhao Wang,Kelvin W.K. Yeung +1 more
TL;DR: The currently available bone grafts and bone substitutes as well as the biological and bio-inorganic factors for the treatments of bone defect are reviewed.
Copper-containing mesoporous bioactive glass scaffolds with multifunctional properties of angiogenesis capacity, osteostimulation and antibacterial activity
TL;DR: It is demonstrated that it is possible to develop multifunctional scaffolds by combining enhanced angiogenesis potential, osteostimulation, and antibacterial properties for the treatment of large bone defects.
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Additive manufacturing of biomaterials.
TL;DR: Key additive manufacturing methods are first introduced followed by AM of different materials, and finally applications of AM in various treatment options are reviewed.
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Bioactive Glasses: Sprouting Angiogenesis in Tissue Engineering
Saeid Kargozar,Francesco Baino,Sepideh Hamzehlou,Sepideh Hamzehlou,Robert G. Hill,Masoud Mozafari +5 more
TL;DR: The salient features, the hurdles that must be overcome, and the hopes and constraints for the development of BGs with improved angiogenetic properties are introduced.
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Biomimetic Materials and Fabrication Approaches for Bone Tissue Engineering.
Hwan Kim,Sivashanmugam Amirthalingam,Seung Hyun Kim,Seung-Hun Lee,Jayakumar Rangasamy,Nathaniel S. Hwang +5 more
TL;DR: In this article, a progress report of biomimetic materials and fabrication approaches that are currently being utilized for biomimic scaffold design are reviewed, including 3D printing methods, for optimal host stem cell infiltration, vascularization, nutrient transfer, and stem cell differentiation.
References
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Strontium-containing hydroxyapatite bioactive bone cement in revision hip arthroplasty.
Guoxin Ni,Kwong Yuen Chiu,William W. Lu,Ying Wang,Yu Zhang,L.B. Hao,Zhaoyang Li,W.M. Lam,S.B. Lu,Keith D. K. Luk +9 more
TL;DR: In vivo study suggested that Sr-HA bioactive bone cement was superior to PMMA bone cement in terms of bone-bonding strength, and compared outcomes with polymethylmethacrylate (PMMA) bone cement.
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Action of boron at the molecular level: effects on transcription and translation in an acellular system.
TL;DR: It is found that 10 mM boric acid greatly increased RNA synthesis, measured by absorbance at 260 nm (×6.4) or by [3H]-UTP uptake (×11).
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Strontium ranelate inhibits key factors affecting bone remodeling in human osteoarthritic subchondral bone osteoblasts
TL;DR: This study provides new insights into the mode of action of strontium ranelate on the metabolism of human OA OA subchondral bone osteoblasts, and suggests that RANKL-3, in contrast to RANKl-1, prevents such membranous localization.
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In vivo study of porous strontium-doped calcium polyphosphate scaffolds for bone substitute applications.
TL;DR: Investigation in vivo biocompatibility and osteogenesis as well as degradability of the porous strontium-doped calcium polyphosphate (SCPP) scaffolds as a biomaterial for bone substitute applications demonstrated that SCPP scaffold can be considered as aBiocompatible material, making it attractive for bone substitutes application purposes.
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The effect of Cu(II)-loaded brushite scaffolds on growth and activity of osteoblastic cells
TL;DR: Results show that Cu(II) enhances cell activity and proliferation of osteoblastic cells on CPC and furthermore affects the expression of several bone specific proteins such as bone sialo protein or osteocalcin and may offer a promising alternative to protein based modification to stimulate cellular activity for an improved bone healing.