B
Brian E. Kalmbach
Researcher at Allen Institute for Brain Science
Publications - 50
Citations - 2011
Brian E. Kalmbach is an academic researcher from Allen Institute for Brain Science. The author has contributed to research in topics: Biology & Neocortex. The author has an hindex of 19, co-authored 41 publications receiving 1093 citations. Previous affiliations of Brian E. Kalmbach include University of Texas at Austin & University of Texas Health Science Center at Houston.
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Journal ArticleDOI
Comparative cellular analysis of motor cortex in human, marmoset and mouse
Trygve E. Bakken,Nikolas L. Jorstad,Qiwen Hu,Blue B. Lake,Wei Tian,Brian E. Kalmbach,Brian E. Kalmbach,Megan Crow,Rebecca D. Hodge,Fenna M. Krienen,Staci A. Sorensen,Jeroen Eggermont,Zizhen Yao,Brian D. Aevermann,Andrew Aldridge,Anna Bartlett,Darren Bertagnolli,Tamara Casper,Rosa Castanon,Kirsten Crichton,Tanya L. Daigle,Rachel A. Dalley,Nick Dee,Nikolai C. Dembrow,Nikolai C. Dembrow,Dinh Diep,Songlin Ding,Weixiu Dong,Rongxin Fang,Stephan Fischer,Melissa Goldman,Jeff Goldy,Lucas T. Graybuck,Brian R. Herb,Xiaomeng Hou,Jayaram Kancherla,Matthew Kroll,Kanan Lathia,Baldur van Lew,Yang Eric Li,Yang Eric Li,Christine S. Liu,Christine S. Liu,Hanqing Liu,Jacinta Lucero,Anup Mahurkar,Delissa McMillen,Jeremy A. Miller,Marmar Moussa,Joseph R. Nery,Philip R. Nicovich,Sheng-Yong Niu,Sheng-Yong Niu,Joshua Orvis,Julia K. Osteen,Scott F. Owen,C. Palmer,C. Palmer,Thanh Pham,Nongluk Plongthongkum,Olivier Poirion,Nora Reed,Christine Rimorin,Angeline Rivkin,William J. Romanow,Adriana E. Sedeno-Cortes,Kimberly Siletti,Saroja Somasundaram,Josef Sulc,Michael Tieu,Amy Torkelson,Herman Tung,Xinxin Wang,Fangming Xie,Anna Marie Yanny,Renee Zhang,Seth A. Ament,M. Margarita Behrens,Héctor Corrada Bravo,Jerold Chun,Alexander Dobin,Jesse Gillis,Ronna Hertzano,Patrick R. Hof,Thomas Höllt,Gregory D. Horwitz,C. Dirk Keene,Peter V. Kharchenko,Andrew L. Ko,Andrew L. Ko,Boudewijn P. F. Lelieveldt,Boudewijn P. F. Lelieveldt,Chongyuan Luo,Eran A. Mukamel,Antonio Pinto-Duarte,Sebastian Preissl,Aviv Regev,Bing Ren,Bing Ren,Richard H. Scheuermann,Richard H. Scheuermann,Richard H. Scheuermann,Kimberly A. Smith,William J. Spain,William J. Spain,Owen White,Christof Koch,Michael Hawrylycz,Bosiljka Tasic,Evan Z. Macosko,Steven A. McCarroll,Steven A. McCarroll,Jonathan T. Ting,Jonathan T. Ting,Hongkui Zeng,Kun Zhang,Guoping Feng,Guoping Feng,Guoping Feng,Joseph R. Ecker,Sten Linnarsson,Ed S. Lein +121 more
TL;DR: The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally conserved across mammals using high-throughput transcriptomic and epigenomic profiling of more than 450k single nuclei in humans, marmoset monkeys and mice as mentioned in this paper.
Posted ContentDOI
A multimodal cell census and atlas of the mammalian primary motor cortex
Ricky S. Adkins,Andrew Aldridge,Shona Allen,Seth A. Ament,Xu An,Ethan J. Armand,Giorgio A. Ascoli,Trygve E. Bakken,Anita Bandrowski,Samik Banerjee,Nikolaos Barkas,Anna Bartlett,Helen S. Bateup,M. Margarita Behrens,Philipp Berens,Jim Berg,Matteo Bernabucci,Yves Bernaerts,Darren Bertagnolli,Tommaso Biancalani,Lara Boggeman,Sina Booeshaghi,Ian Bowman,Héctor Corrada Bravo,Cathryn R. Cadwell,Edward M. Callaway,Benjamin Carlin,Carolyn O’Connor,Robert A. Carter,Tamara Casper,Rosa Castanon,Jesus Ramon Castro,Rebecca K. Chance,Apaala Chatterjee,Huaming Chen,Jerold Chun,Carlo Colantuoni,Jonathan Crabtree,Heather Huot Creasy,Kirsten Crichton,Megan Crow,Florence D’Orazi,Tanya L. Daigle,Rachel A. Dalley,Nick Dee,Kylee Degatano,Benjamin Dichter,Dinh Diep,Liya Ding,Songlin Ding,Bertha Dominguez,Hong-Wei Dong,Weixiu Dong,Elizabeth L. Dougherty,Sandrine Dudoit,Joseph R. Ecker,Stephen W. Eichhorn,Rongxin Fang,Victor Felix,Guoping Feng,Zhao Feng,Stephan Fischer,Conor Fitzpatrick,Olivia Fong,Nicholas N. Foster,William Galbavy,James C. Gee,Satrajit S. Ghosh,Michelle G. Giglio,Thomas R. Gillespie,Jesse Gillis,Melissa Goldman,Jeff Goldy,Hui Gong,Lin Gou,Michael Grauer,Yaroslav O. Halchenko,Julie M. Harris,Leonard Hartmanis,Joshua T. Hatfield,Michael Hawrylycz,Brian Helba,Brian R. Herb,Ronna Hertzano,Houri Hintiryan,Karla E. Hirokawa,Dirk Hockemeyer,Rebecca D. Hodge,Greg Hood,Gregory D. Horwitz,Xiaomeng Hou,Lijuan Hu,Qiwen Hu,Josh Huang,Bing-Xing Huo,Tony Ito-Cole,Matthew W. Jacobs,Xueyan Jia,Shengdian Jiang,Tao Jiang,Xiaolong Jiang,Xin Jin,Nikolas L. Jorstad,Brian E. Kalmbach,Jayaram Kancherla,C. Dirk Keene,Kathleen Kelly,Farzaneh Khajouei,Peter V. Kharchenko,Gukhan Kim,Andrew L. Ko,Dmitry Kobak,Kishori Konwar,Daniel J. Kramer,Fenna M. Krienen,Matthew Kroll,Xiuli Kuang,Hsien-Chi Kuo,Rachael Larsen,Kanan Lathia,Sophie Laturnus,Angus Y. Lee,Cheng-Ta Lee,Kuo-Fen Lee,Ed S. Lein,Phil Lesnar,Anan Li,Xiangning Li,Xu Li,Yang Eric Li,Yaoyao Li,Yuanyuan Li,Byung Kook Lim,Sten Linnarsson,Christine S. Liu,Hanqing Liu,Lijuan Liu,Jacinta Lucero,Chongyuan Luo,Qingming Luo,Evan Z. Macosko,Anup Mahurkar,Maryann E. Martone,Katherine Matho,Steven A. McCarroll,Carrie McCracken,Delissa McMillen,Elanine Miranda,Partha P. Mitra,Paula Assakura Miyazaki,Judith Mizrachi,Stephanie Mok,Eran A. Mukamel,Shalaka Mulherkar,Naeem Nadaf,Maitham Naeemi,Arun Narasimhan,Joseph R. Nery,Lydia Ng,John Ngai,Thuc Nghi Nguyen,Lance Nickel,Philip R. Nicovich,Sheng-Yong Niu,Vasilis Ntranos,Michael Nunn,Dustin Olley,Joshua Orvis,Julia K. Osteen,Pavel Osten,Scott F. Owen,Lior Pachter,Ramesh Palaniswamy,C. Palmer,Yan Pang,Hanchuan Peng,Thanh Pham,Antonio Pinto-Duarte,Nongluk Plongthongkum,Olivier Poirion,Sebastian Preissl,Elizabeth Purdom,Lei Qu,Mohammad S. Rashid,Nora Reed,Aviv Regev,Bing Ren,Miao Ren,Christine Rimorin,Davide Risso,Angeline Rivkin,Rodrigo Muñoz-Castañeda,William J. Romanow,Alexander J. Ropelewski,Hector Roux de Bézieux,Zongcai Ruan,Rickard Sandberg,Steven Savoia,Federico Scala,Michael Schor,Elise Shen,Kimberly Siletti,Jared B. Smith,Kimberly A. Smith,Saroja Somasundaram,Yuanyuan Song,Staci A. Sorensen,David A. Stafford,Kelly Street,Josef Sulc,Susan M. Sunkin,Valentine Svensson,Pengcheng Tan,Zheng Huan Tan,Bosiljka Tasic,Carol L. Thompson,Wei Tian,Timothy L. Tickle,Michael Tieu,Jonathan T. Ting,Andreas S. Tolias,Amy Torkelson,Herman Tung,Eeshit Dhaval Vaishnav,Koen Van den Berge,Cindy T. J. van Velthoven,Charles R. Vanderburg,Matthew B. Veldman,Minh Vu,Wayne Wakeman,Peng Wang,Quanxin Wang,Xinxin Wang,Yimin Wang,Yun Wang,Joshua D. Welch,Owen White,Elora W Williams,Fangming Xie,Peng Xie,Feng Xiong,William Yang,Anna Marie Yanny,Zizhen Yao,Lulu Yin,Yang Yu,Jing Yuan,Hongkui Z +247 more
TL;DR: This study reveals a unified molecular genetic landscape of cortical cell types that congruently integrates their transcriptome, open chromatin and DNA methylation maps, and establishes a unified and mechanistic framework of neuronal cell type organization that integrates multi-layered molecular genetic and spatial information with multi-faceted phenotypic properties.
Journal ArticleDOI
Interactions between prefrontal cortex and cerebellum revealed by trace eyelid conditioning.
TL;DR: It is suggested that trace eyelid conditioning involves an interaction between the persistent activity of delay cells in mPFC-a putative mechanism of working memory-and motor learning in the cerebellum.
Journal ArticleDOI
h-Channels Contribute to Divergent Intrinsic Membrane Properties of Supragranular Pyramidal Neurons in Human versus Mouse Cerebral Cortex.
Brian E. Kalmbach,Brian E. Kalmbach,Anatoly Buchin,Brian Long,Jennie L. Close,Anirban Nandi,Jeremy A. Miller,Trygve E. Bakken,Rebecca D. Hodge,Peter Chong,Rebecca de Frates,Kael Dai,Zoe Maltzer,Philip R. Nicovich,C. Dirk Keene,Daniel L. Silbergeld,Ryder P. Gwinn,Charles Cobbs,Andrew L. Ko,Andrew L. Ko,Jeffrey G. Ojemann,Jeffrey G. Ojemann,Christof Koch,Costas A. Anastassiou,Costas A. Anastassiou,Ed S. Lein,Ed S. Lein,Jonathan T. Ting +27 more
TL;DR: Biophysical modeling and single-cell/nucleus RNA sequencing provide evidence that h-channels promote the transfer of theta frequencies from dendrite-to-soma in human L3 pyramidal neurons, contributing to between-species differences in a fundamental neuronal property.
Journal ArticleDOI
Specialized subpopulations of deep-layer pyramidal neurons in the neocortex: Bridging cellular properties to functional consequences
Arielle L. Baker,Brian E. Kalmbach,Mieko Morishima,Juhyun Kim,Ashley L. Juavinett,Nuo Li,Nikolai C. Dembrow +6 more
TL;DR: This Viewpoints article summarizes the current knowledge about DLPNs and highlights recent work elucidating the functional differences between DLPN subpopulations.