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Garrett Hellenthal

Researcher at University College London

Publications -  76
Citations -  11454

Garrett Hellenthal is an academic researcher from University College London. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 34, co-authored 70 publications receiving 9592 citations. Previous affiliations of Garrett Hellenthal include University of Oxford & Wellcome Trust Centre for Human Genetics.

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Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Stephen Sawcer, +265 more
- 10 Aug 2011 - 
TL;DR: In this article, a collaborative GWAS involving 9,772 cases of European descent collected by 23 research groups working in 15 different countries, they have replicated almost all of the previously suggested associations and identified at least a further 29 novel susceptibility loci.
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Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

Ashley Beecham, +206 more
- 01 Nov 2013 - 
TL;DR: This study enhances the catalog of multiple sclerosis risk variants and illustrates the value of fine mapping in the resolution of GWAS signals.
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Inference of population structure using dense haplotype data

TL;DR: A novel inference framework that aims to efficiently capture information on population structure provided by patterns of haplotype similarity and an efficient model-based approach to identify discrete populations using this matrix, which offers advantages over PCA and over existing clustering algorithms in terms of speed, number of separable populations, and sensitivity to subtle population structure.
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Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

Lam C. Tsoi, +215 more
- 01 Dec 2012 - 
TL;DR: A meta-analysis of genome-wide association studies and independent data sets genotyped on the Immunochip identified 15 new susceptibility loci, increasing to 36 the number associated with psoriasis in European individuals, and identified five independent signals within previously known loci.
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A genetic atlas of human admixture history.

TL;DR: An atlas of worldwide human admixture history, constructed by using genetic data alone and encompassing over 100 events occurring over the past 4000 years, is revealed, revealing admixture to be an almost universal force shaping human populations.