G
Garrett Hellenthal
Researcher at University College London
Publications - 76
Citations - 11454
Garrett Hellenthal is an academic researcher from University College London. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 34, co-authored 70 publications receiving 9592 citations. Previous affiliations of Garrett Hellenthal include University of Oxford & Wellcome Trust Centre for Human Genetics.
Papers
More filters
Journal ArticleDOI
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
Douglas M. Ruderfer,Stephan Ripke,Stephan Ripke,Stephan Ripke,Andrew McQuillin,James Boocock,Eli A. Stahl,Jennifer M. Whitehead Pavlides,Niamh Mullins,Alexander W. Charney,Anil P.S. Ori,Loes M. Olde Loohuis,Enrico Domenici,Arianna Di Florio,Sergi Papiol,Janos Kalman,Vassily Trubetskoy,Rolf Adolfsson,Ingrid Agartz,Ingrid Agartz,Esben Agerbo,Esben Agerbo,Huda Akil,Diego Albani,Margot Albus,Martin Alda,Martin Alda,Madeline Alexander,Ney Alliey-Rodriguez,Thomas Damm Als,Thomas Damm Als,Farooq Amin,Farooq Amin,Adebayo Anjorin,Maria Arranz,Maria Arranz,Swapnil Awasthi,Silviu Alin Bacanu,Judith A. Badner,Marie Bækvad-Hansen,Steven C. Bakker,Gavin Band,Jack D. Barchas,Inês Barroso,Nicholas Bass,Michael Bauer,Bernhard T. Baune,Martin Begemann,Céline Bellenguez,Richard A. Belliveau,Frank Bellivier,Stephan Bender,Judit Bene,Sarah E. Bergen,Sarah E. Bergen,Wade H. Berrettini,Elizabeth Bevilacqua,Joanna M. Biernacka,Tim B. Bigdeli,Donald W. Black,Hannah Blackburn,Jenefer M. Blackwell,Jenefer M. Blackwell,Douglas Blackwood,Carsten Bøcker Pedersen,Carsten Bøcker Pedersen,Michael Boehnke,Marco P. Boks,Anders D. Børglum,Anders D. Børglum,Elvira Bramon,Elvira Bramon,Gerome Breen,Gerome Breen,Matthew A. Brown,Richard Bruggeman,Nancy G. Buccola,Randy L. Buckner,Monika Budde,Brendan Bulik-Sullivan,Brendan Bulik-Sullivan,Suzannah Bumpstead,William E. Bunney,Margit Burmeister,Joseph D. Buxbaum,Jonas Bybjerg-Grauholm,William Byerley,Wiepke Cahn,Guiqing Cai,Murray J. Cairns,Dominique Campion,Rita M. Cantor,Vaughan J. Carr,Noa Carrera,Juan P. Casas,Juan P. Casas,Miquel Casas,Miquel Casas,Stanley V. Catts,Pablo Cervantes,Kimberley D. Chambert,Raymond C.K. Chan,Eric Y.H. Chen,Ronald Y.L. Chen,Wei Cheng,Eric F.C. Cheung,Siow Ann Chong,Toni-Kim Clarke,C. Robert Cloninger,David Cohen,Nadine Cohen,Jonathan R. I. Coleman,Jonathan R. I. Coleman,David A. Collier,David A. Collier,Paul Cormican,William Coryell,Nicholas John Craddock,David Craig,Benedicto Crespo-Facorro,James J. Crowley,Cristiana Cruceanu,David Curtis,David Curtis,Piotr M. Czerski,Anders M. Dale,Mark J. Daly,Mark J. Daly,Udo Dannlowski,Ariel Darvasi,Michael Davidson,Kenneth L. Davis,Christiaan de Leeuw,Franziska Degenhardt,Jurgen Del Favero,Lynn E. DeLisi,Panos Deloukas,Ditte Demontis,Ditte Demontis,J. Raymond DePaulo,Marta Di Forti,Dimitris Dikeos,Timothy G. Dinan,Srdjan Djurovic,Amanda Dobbyn,Peter Donnelly,Gary Donohoe,Gary Donohoe,Elodie Drapeau,Serge Dronov,Jubao Duan,Jubao Duan,Frank Dudbridge,Audrey Duncanson,Howard J. Edenberg,Sarah Edkins,Hannelore Ehrenreich,Peter Eichhammer,Torbjørn Elvsåshagen,Johan G. Eriksson,Valentina Escott-Price,Tõnu Esko,Tõnu Esko,Tõnu Esko,Laurent Essioux,Bruno Etain,Chun Chieh Fan,Kai-How Farh,Martilias S. Farrell,Matthew Flickinger,Tatiana Foroud,Liz Forty,Josef Frank,Lude Franke,Christine Fraser,Robert Freedman,Colin Freeman,Nelson B. Freimer,Joseph I. Friedman,Menachem Fromer,Menachem Fromer,Menachem Fromer,Mark A. Frye,Janice M. Fullerton,Janice M. Fullerton,Katrin Gade,Katrin Gade,Julie Garnham,Helena Gaspar,Pablo V. Gejman,Pablo V. Gejman,Giulio Genovese,Lyudmila Georgieva,Claudia Giambartolomei,Eleni Giannoulatou,Ina Giegling,Ina Giegling,Michael Gill,Matthew Gillman,Marianne Giørtz Pedersen,Paola Giusti-Rodríguez,Stephanie Godard,Fernando S. Goes,Jacqueline I. Goldstein,Jacqueline I. Goldstein,Srihari Gopal,Scott D. Gordon,Katherine Gordon-Smith,Jacob Gratten,Emma Gray,Elaine K. Green,Melissa J. Green,Tiffany A. Greenwood,Maria Grigoroiu-Serbanescu,Jakob Grove,Jakob Grove,Weihua Guan,Hugh Gurling,Jose Guzman Parra,Rhian Gwilliam,Lieuwe de Haan,Jeremy Hall,Mei-Hua Hall,Christian Hammer,Naomi Hammond,Marian L. Hamshere,Mark Hansen,Thomas Hansen,Vahram Haroutunian,Vahram Haroutunian,Annette M. Hartmann,Joanna Hauser,Martin Hautzinger,Urs Heilbronner,Garrett Hellenthal,Frans Henskens,Stefan Herms,Stefan Herms,Maria Hipolito,Joel N. Hirschhorn,Joel N. Hirschhorn,Per Hoffmann,Per Hoffmann,Mads V. Hollegaard,David M. Hougaard,Hailiang Huang,Hailiang Huang,Laura M. Huckins,Christina M. Hultman,Sarah E. Hunt,Masashi Ikeda,Nakao Iwata,Conrad Iyegbe,Assen Jablensky,Stéphane Jamain,Janusz Jankowski,Alagurevathi Jayakumar,Inge Joa,Ian Jones,Lisa Jones,Erik G. Jönsson,Erik G. Jönsson,Antonio Julià,Anders Juréus,Anna K. Kähler,René S. Kahn,René S. Kahn,Luba Kalaydjieva,Radhika Kandaswamy,Sena Karachanak-Yankova,Juha Karjalainen,Robert Karlsson,David J. Kavanagh,Matthew C. Keller,Brian Kelly,John R. Kelsoe,James L. Kennedy,Andrey Khrunin,Yunjung Kim,George Kirov,Sarah Kittel-Schneider,Janis Klovins,Jo Knight,Sarah Knott,James A. Knowles,James A. Knowles,Manolis Kogevinas,Bettina Konte,Eugenia Kravariti,Vaidutis Kučinskas,Zita Ausrele Kucinskiene,Ralph Kupka,Ralph Kupka,Hana Kuzelova-Ptackova,Mikael Landén,Mikael Landén,Cordelia Langford,Claudine Laurent,Claudine Laurent,Jacob Lawrence,Stephen M. Lawrie,William Lawson,Markus Leber,Marion Leboyer,Marion Leboyer,Phil Lee,Phil Lee,Jimmy Lee Chee Keong,Sophie E. Legge,Todd Lencz,Todd Lencz,Bernard Lerer,Douglas F. Levinson,Shawn Levy,Cathryn M. Lewis,Cathryn M. Lewis,Jun Li,Miaoxin Li,Qingqin S. Li,Tao Li,Kung-Yee Liang,Jennifer Liddle,Jeffrey A. Lieberman,Svetlana A. Limborska,Kuang Lin,Don H. Linszen,Jolanta Lissowska,Chunyu Liu,Jianjun Liu,Jianjun Liu,Jouko Lönnqvist,Carmel M. Loughland,Jan Lubinski,Susanne Lucae,Milan Macek,Donald J. MacIntyre,Donald J. MacIntyre,Patrik K. E. Magnusson,Brion S. Maher,Pamela B. Mahon,Pamela B. Mahon,Wolfgang Maier,Anil K. Malhotra,Anil K. Malhotra,J. Mallet,Ulrik Fredrik Malt,Hugh S. Markus,Sara Marsal,Nicholas G. Martin,Nicholas G. Martin,Ignacio Mata,Christopher G. Mathew,Manuel Mattheisen,Morten Mattingsdal,Fermín Mayoral,Owen T. McCann,Robert W. McCarley,Steven A. McCarroll,Steven A. McCarroll,Mark I. McCarthy,Colm McDonald,Susan L. McElroy,Peter McGuffin,Melvin G. McInnis,Andrew M. McIntosh,James McKay,Francis J. McMahon,Helena Medeiros,Sarah E. Medland,Sandra Meier,Carin J. Meijer,Béla Melegh,Ingrid Melle,Fan Meng,Raquelle I. Mesholam-Gately,Andres Metspalu,Patricia T. Michie,Lili Milani,Vihra Milanova,Philip B. Mitchell,Younes Mokrab,Grant W. Montgomery,Jennifer L. Moran,Gunnar Morken,Derek W. Morris,Derek W. Morris,Ole Mors,Ole Mors,Preben Bo Mortensen,Preben Bo Mortensen,Bryan J. Mowry,Thomas W. Mühleisen,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Kieran C. Murphy,Robin M. Murray,Richard M. Myers,Inez Myin-Germeys,Benjamin M. Neale,Benjamin M. Neale,Mari Nelis,Igor Nenadic,Deborah A. Nertney,Gerald Nestadt,Kristin K. Nicodemus,Caroline M. Nievergelt,Caroline M. Nievergelt,Liene Nikitina-Zake,Vishwajit L. Nimgaonkar,Laura Nisenbaum,Merete Nordentoft,Annelie Nordin,Markus M. Nöthen,Evaristus A. Nwulia,Eadbhard O'Callaghan,Claire O'Donovan,Colm O'Dushlaine,F. Anthony O'Neill,Ketil J. Oedegaard,Sang-Yun Oh,Ann Olincy,Line Olsen,Lilijana Oruc,Jim van Os,Jim van Os,Michael John Owen,Sara A. Paciga,Colin N. A. Palmer,Aarno Palotie,Aarno Palotie,Aarno Palotie,Christos Pantelis,George N. Papadimitriou,Elena Parkhomenko,Carlos N. Pato,Michele T. Pato,Tiina Paunio,Tiina Paunio,Richard G. Pearson,Diana O. Perkins,Roy H. Perlis,Amy Perry,Tune H. Pers,Tune H. Pers,Tune H. Pers,Tracey L. Petryshen,Tracey L. Petryshen,Andrea Pfennig,Marco Picchioni,Olli Pietiläinen,Olli Pietiläinen,Jonathan Pimm,Matti Pirinen,Robert Plomin,Andrew Pocklington,Danielle Posthuma,Danielle Posthuma,James B. Potash,Simon C. Potter,John Powell,Alkes L. Price,Alkes L. Price,Ann E. Pulver,Shaun Purcell,Shaun Purcell,Digby Quested,Josep Antoni Ramos-Quiroga,Josep Antoni Ramos-Quiroga,Henrik B. Rasmussen,Anna Rautanen,Radhi Ravindrarajah,Eline J. Regeer,Abraham Reichenberg,Andreas Reif,Mark Reimers,Marta Ribasés,Marta Ribasés,John P. Rice,Alexander Richards,Michelle Ricketts,Brien P. Riley,Fabio Rivas,Margarita Rivera,Margarita Rivera,Joshua L. Roffman,Guy A. Rouleau,Panos Roussos,Dan Rujescu,Dan Rujescu,Veikko Salomaa,Cristina Sánchez-Mora,Cristina Sánchez-Mora,Alan R. Sanders,Alan R. Sanders,Stephen Sawcer,Ulrich Schall,Alan F. Schatzberg,William A. Scheftner,Peter R. Schofield,Peter R. Schofield,Nicholas J. Schork,Sibylle G. Schwab,Edward M. Scolnick,Laura J. Scott,Rodney J. Scott,Larry J. Seidman,Alessandro Serretti,Pak C. Sham,Cynthia Shannon Weickert,Cynthia Shannon Weickert,Tatyana Shehktman,Jianxin Shi,Paul D. Shilling,Engilbert Sigurdsson,Jeremy M. Silverman,Jeremy M. Silverman,Kang Sim,Claire Slaney,Petr Slominsky,Olav B. Smeland,Olav B. Smeland,Jordan W. Smoller,Jordan W. Smoller,Hon-Cheong So,Janet L. Sobell,Erik Söderman,Christine Søholm Hansen,Chris C. A. Spencer,Anne T. Spijker,David St Clair,Hreinn Stefansson,Kari Stefansson,Kari Stefansson,Stacy Steinberg,Elisabeth Stögmann,Eystein Stordal,Amy Strange,Richard E. Straub,John Strauss,Fabian Streit,Eric Strengman,Jana Strohmaier,T. Scott Stroup,Zhan Su,Mythily Subramaniam,Jaana Suvisaari,Dragan M. Svrakic,Jin P. Szatkiewicz,Szabolcs Szelinger,Avazeh Tashakkori-Ghanbaria,Srinivas Thirumalai,Robert C. Thompson,Thorgeir E. Thorgeirsson,Draga Toncheva,Paul A. Tooney,Sarah Tosato,Timothea Toulopoulou,Richard C. Trembath,Jens Treutlein,Gustavo Turecki,Arne E. Vaaler,Helmut Vedder,Eduard Vieta,John B. Vincent,Peter M. Visscher,Ananth C. Viswanathan,Ananth C. Viswanathan,Damjan Vukcevic,John L. Waddington,Matthew Waller,Dermot Walsh,Muriel Walshe,James T.R. Walters,Dai Wang,Qiang Wang,Weiqing Wang,Yunpeng Wang,Stanley J. Watson,Bradley T. Webb,Thomas W. Weickert,Thomas W. Weickert,Daniel R. Weinberger,Matthias Weisbrod,Mark Weiser,Thomas Werge,Thomas Werge,Paul A. Weston,Pamela Whittaker,Sara Widaa,Durk Wiersma,Dieter B. Wildenauer,Nigel Williams,Stephanie Williams,Stephanie H. Witt,Aaron R. Wolen,Emily H. M. Wong,Nicholas W. Wood,Brandon Wormley,Jing Qin Wu,Simon Xi,Wei Xu,Wei Xu,Allan H. Young,Clement C. Zai,Peter P. Zandi,Peng Zhang,Xuebin Zheng,Fritz Zimprich,Sebastian Zöllner,Aiden Corvin,Ayman H. Fanous,Sven Cichon,Sven Cichon,Marcella Rietschel,Elliot S. Gershon,Thomas G. Schulze,Alfredo B. Cuellar-Barboza,Alfredo B. Cuellar-Barboza,Andreas J. Forstner,Andreas J. Forstner,Peter Holmans,John I. Nurnberger,Ole A. Andreassen,S. Hong Lee,Michael Conlon O'Donovan,Patrick F. Sullivan,Patrick F. Sullivan,Roel A. Ophoff,Roel A. Ophoff,Naomi R. Wray,Pamela Sklar,Kenneth S. Kendler +631 more
TL;DR: For the first time, specific loci that distinguish between BD and SCZ are discovered and polygenic components underlying multiple symptom dimensions are identified that point to the utility of genetics to inform symptomology and potential treatment.
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
Lam C. Tsoi,Sarah L. Spain,Jo Knight,Eva Ellinghaus,Philip E. Stuart,Francesca Capon,Jun Ding,Yun Li,Trilokraj Tejasvi,Johann E. Gudjonsson,Hyun Min Kang,Mariet Allen,Ross McManus,Giuseppe Novelli,Lena Samuelsson,J. Schalkwijk,Mona Ståhle,A D Burden,Catherine H. Smith,Michael J. Cork,Xavier Estivill,Anne M. Bowcock,Gerald G. Krueger,Wolfgang Weger,Jane Worthington,Rachid Tazi-Ahnini,Frank O. Nestle,Adrian Hayday,Per Hoffmann,Juliane Winkelmann,Cisca Wijmenga,Cordelia Langford,Sarah Edkins,Ross M. Andrews,H. D. Blackburn,A. Strange,Richard D. Pearson,Damjan Vukcevic,Chris C. A. Spencer,Panagiotis Deloukas,Ulrich Mrowietz,Stefan Schreiber,Stephan Weidinger,Sulev Kõks,Külli Kingo,Tõnu Esko,Andres Metspalu,Henry W. Lim,John J. Voorhees,Michael Weichenthal,H. E. Wichmann,Vinod Chandran,Cheryl F. Rosen,Proton Rahman,Dafna D. Gladman,Christopher E.M. Griffiths,André Reis,Juha Kere,R. P. Nnair,Andre Franke,J. Barker,Gonçalo R. Abecasis,J. T. Eelder,R. Ttrembath,Kristina Callis Duffin,Cynthia Helms,David E. Goldgar,Justin Paschall,Mary J. Malloy,Clive R. Pullinger,John P. Kane,Jennifer M. Gardner,A. Perlmutter,Andrew Miner,Bing Jian Feng,Ravi Hiremagalore,Robert W. Ike,Enno Christophers,Tilo Henseler,Andreas Ruether,Steven J. Schrodi,Sampath Prahalad,Stephen L. Guthery,Judith Fischer,Wilson Liao,Pui-Yan Kwok,Alan Menter,G.M. Lathrop,Carol Wise,Ann B. Begovich,Alexandros Onoufriadis,Michael E. Weale,Anne C. Hofer,Wolfgang Salmhofer,Philip A. Wolf,Kati Kainu,Ulpu Saarialho-Kere,Sari Suomela,P. Badorf,Ulrike Hüffmeier,Werner Kurrat,Wolfgang Küster,Jesús Lascorz,Rotraut Mössner,Funda Schürmeier-Horst,Markward Ständer,Horst Traupe,Judith G.M. Bergboer,Martin den Heijer,P.C.M. van de Kerkhof,Patrick L.J.M. Zeeuwen,L. Barnes,Linda E. Campbell,Caitriona Cusack,C. M. Coleman,Judith Conroy,Sean Ennis,Oliver FitzGerald,Phil Gallagher,Alan D. Irvine,Brian Kirby,Trevor Markham,Whi McLean,Joseph McPartlin,Sarah Rogers,Anthony W. Ryan,Agnieszka Zawirska,Emiliano Giardina,Tiziana Lepre,Carlo Perricone,Gemma Martin-Ezquerra,Ramon M. Pujol,Eva Riveira-Muñoz,Annica Inerot,Åsa Torinsson Naluai,Lotus Mallbris,Katarina Wolk,Joyce Leman,Anne Barton,Richard B. Warren,Helen S. Young,Isis Ricaño-Ponce,Gosia Trynka,Fawnda Pellett,A. Henschel,M. Aurand,Bruce F. Bebo,Christian Gieger,Thomas Illig,Susanne Moebus,K. H. Jöckel,Raimund Erbel,Peter Donnelly,Leena Peltonen,Jenefer M. Blackwell,Elvira Bramon,Matthew A. Brown,Juan P. Casas,Aiden Corvin,N. Craddock,Audrey Duncanson,Janusz Jankowski,Hugh S. Markus,Christopher G. Mathew,Mark I. McCarthy,Colin N. A. Palmer,Robert Plomin,Anna Rautanen,Stephen Sawcer,Nilesh J. Samani,Ananth C. Viswanathan,Nicholas W. Wood,Céline Bellenguez,Colin Freeman,Garrett Hellenthal,Eleni Giannoulatou,Matti Pirinen,Zhan Su,Sarah E. Hunt,R. Gwilliam,Suzannah Bumpstead,Serge Dronov,Matthew W. Gillman,Erin Gray,Naomi Hammond,Alagurevathi Jayakumar,O. T. McCann,Jennifer Liddle,Maritza Pérez,Simon C. Potter,Radhi Ravindrarajah,Michelle Ricketts,Matthew Waller,Paul A. Weston,Sara Widaa,Pamela Whittaker,R. P. Neir,J.N.W.N. Barker,James T. Elder,Richard C. Trembath +199 more
TL;DR: A meta-analysis of genome-wide association studies and independent data sets genotyped on the Immunochip identified 15 new susceptibility loci, increasing to 36 the number associated with psoriasis in European individuals, and identified five independent signals within previously known loci.
Journal ArticleDOI
The fine-scale genetic structure of the British population
Stephen Leslie,Stephen Leslie,Bruce Winney,Garrett Hellenthal,Dan Davison,Abdelhamid Boumertit,Tammy Day,Katarzyna Hutnik,Ellen C. Røyrvik,Barry Cunliffe,Daniel Lawson,Daniel Falush,Colin Freeman,Matti Pirinen,Simon Myers,Mark Robinson,Peter Donnelly,Peter Donnelly,Walter F. Bodmer +18 more
TL;DR: There is significant pre-Roman but post-Mesolithic movement into southeastern England from continental Europe, and it is shown that in non-Saxon parts of the United Kingdom, there exist genetically differentiated subgroups rather than a general ‘Celtic’ population.
Journal ArticleDOI
Early farmers from across Europe directly descended from Neolithic Aegeans
Zuzana Hofmanová,Susanne Kreutzer,Garrett Hellenthal,Christian Sell,Yoan Diekmann,David Díez-del-Molino,Lucy van Dorp,Saioa López,Athanasios Kousathanas,Athanasios Kousathanas,Vivian Link,Vivian Link,Karola Kirsanow,Lara M. Cassidy,Rui Martiniano,Melanie Strobel,Amelie Scheu,Amelie Scheu,Kostas Kotsakis,Paul Halstead,Sevi Triantaphyllou,Nina Kyparissi-Apostolika,Dushka Urem-Kotsou,Christina Ziota,Fotini Adaktylou,Shyamalika Gopalan,Dean Bobo,Laura Winkelbach,Jens Blöcher,Martina Unterländer,Christoph Leuenberger,Çiler Çilingiroğlu,Barbara Horejs,Fokke Gerritsen,Stephen Shennan,Daniel G. Bradley,Mathias Currat,Krishna R. Veeramah,Daniel Wegmann,Daniel Wegmann,Mark G. Thomas,Christina Papageorgopoulou,Joachim Burger +42 more
TL;DR: This study demonstrates a direct genetic link between Mediterranean and Central European early farmers and those of Greece and Anatolia, extending the European Neolithic migratory chain all the way back to southwestern Asia.
Journal ArticleDOI
Evidence for substantial fine-scale variation in recombination rates across the human genome.
Dana C. Crawford,Tushar Bhangale,Na Li,Na Li,Garrett Hellenthal,Mark J. Rieder,Deborah A. Nickerson,Matthew Stephens +7 more
TL;DR: A new statistical method is applied, which overcomes limitations, to infer patterns of fine-scale recombination rate variation in 74 genes, and finds extensive rate variation both within and among genes.